World's Best Scientists 2026 revealed!
Leo A. van Grunsven

Leo A. van Grunsven

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
17646
World Ranking
15374
National Ranking
267

Leo A. van Grunsven publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Leo A. van Grunsven sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 154 publications — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Leo A. van Grunsven D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Leo A. van Grunsven sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 54 D-Index — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Leo A. van Grunsven is affiliated with the Vrije Universiteit Brussel in Belgium. Their research primarily focuses on medicine, with significant contributions to biochemistry, genetics, and molecular biology. Within these fields, van Grunsven's work has a strong emphasis on hepatology and molecular biology, alongside interests in epidemiology, surgery, and oncology.

The scientist's main research topics include liver physiology and pathology, liver disease diagnosis and treatment, pluripotent stem cells research, organ transplantation techniques and outcomes, pancreatic function and diabetes, 3D printing in biomedical research, and single-cell and spatial transcriptomics.

Van Grunsven has published extensively, with frequent contributions to several scientific venues. These include:

  • Journal of Hepatology (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • Cell Death and Disease (3 publications)
  • Biomaterials (3 publications)
  • Nature Communications (2 publications)

They have collaborated often with colleagues such as Stefaan Verhulst, Catherine M. Verfaillie, Ayla Smout, Vincent De Smet, and Nathalie Eysackers.

Recent selected papers include:

  • "Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis" (2020, Gastroenterology)
  • "Hippo signaling instructs ectopic but not normal organ growth" (2022, Science)
  • "Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis" (2021, Cell Metabolism)
  • "Initiation of hepatic stellate cell activation extends into chronic liver disease" (2021, Cell Death and Disease)
  • "Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis" (2020, Expert Opinion on Pharmacotherapy)

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

    Johnny Bonnardel;Wouter T’Jonck;Djoere Gaublomme;Robin Browaeys

  • A role for autophagy during hepatic stellate cell activation.

    Lien F.R. Thoen;Eduardo L.M. Guimarães;Laurent Dollé;Inge Mannaerts

  • The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

    Inge Mannaerts;Sofia Batista Leite;Stefaan Verhulst;Sofie Sofie Claerhout

  • Keratin 19: a key role player in the invasion of human hepatocellular carcinomas

    Olivier Govaere;Mina Komuta;Johannes Berkers;Bart Spee

  • Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells.

    Eduardo L.M. Guimarães;Christophe Empsen;Albert Geerts;Leo A. van Grunsven

  • Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro

    Sofia B. Leite;Tiffany Roosens;Adil El Taghdouini;Inge Mannaerts

  • Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design.

    Kevin Buyens;Stefaan C. De Smedt;Kevin Braeckmans;Joseph Demeester

  • FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis

    Len Verbeke;Inge Mannaerts;Robert Schierwagen;Olivier Govaere

  • Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

    Mar Coll;Luis Perea;Ruben Boon;Sofia B. Leite

  • The Biliary Epithelium Gives Rise to Liver Progenitor Cells

    Daniel Rodrigo-Torres;Silvia Affò;Mar Coll;Oriol Morales-Ibanez

  • Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

    Iván M. Moya;Iván M. Moya;Stéphanie A. Castaldo;Laura van den Mooter;Soheil Soheily

  • 3D in vitro models of liver fibrosis

    Leo A van Grunsven

  • Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo.

    Inge Mannaerts;Nele Nuytten;Vera Rogiers;Karin Vanderkerken

  • Atypical Mowat–Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex

    Griet Verstappen;Leonardus Van Grunsven;Leonardus Van Grunsven;Christine Michiels;Christine Michiels;Tom Van de Putte;Tom Van de Putte

  • Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.

    Olivier Govaere;Jasper Wouters;Michaela Petz;Yves-Paul Vandewynckel

  • EpCAM and the biology of hepatic stem/progenitor cells

    Laurent Dollé;Neil D. Theise;Eva Schmelzer;Luke Boulter

  • Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells

    Zhenan Liu;Leo A. van Grunsven;Elke Van Rossen;Ben Schroyen

  • Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice.

    Christophe Van Steenkiste;Jordi Ribera;Anja Geerts;Montse Pauta

  • The quest for liver progenitor cells: a practical point of view.

    Laurent Dollé;Jan Best;Jie Mei;Feras Al Battah

Frequent Co-Authors

Etienne Sokal
Etienne Sokal Université Catholique de Louvain
Tania Roskams
Tania Roskams KU Leuven
Laurence Lagneaux
Laurence Lagneaux Université Libre de Bruxelles
Georg Halder
Georg Halder KU Leuven
James C. Smith
James C. Smith The Francis Crick Institute
Juan José Lozano
Juan José Lozano Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
Vera Rogiers
Vera Rogiers Vrije Universiteit Brussel
Mathieu Vinken
Mathieu Vinken Vrije Universiteit Brussel

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