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Biology and Biochemistry

D-Index
62
Citations
12760
World Ranking
10870
National Ranking
376

Overview

Niels C. Bols is affiliated with the University of Waterloo in Canada. The primary areas of research focus on immunology and microbiology, with particular emphasis on subfields including immunology, genetics, ecology, aquatic science, and molecular biology.

Their research topics encompass:

  • Aquaculture disease management and microbiota
  • Physiological and biochemical adaptations
  • Aquaculture nutrition and growth
  • Antimicrobial peptides and activities
  • Interferon and immune responses
  • Immune response and inflammation
  • Animal genetics and reproduction

Niels C. Bols has published in several scientific venues, with frequent appearances in:

  • In Vitro Cellular & Developmental Biology - Animal
  • Pathogens
  • Journal of Fish Diseases
  • Developmental & Comparative Immunology
  • Journal of Thermal Biology

Selected recent papers authored or co-authored by Bols include:

  • Distinguishing between ante factum and post factum properties of animal cell lines and demonstrating their use in grouping ray-finned fish cell lines into invitromes, 2023, In Vitro Cellular & Developmental Biology - Animal
  • Screening of Fish Cell Lines for Piscine Orthoreovirus-1 (PRV-1) Amplification: Identification of the Non-Supportive PRV-1 Invitrome, 2020, Pathogens
  • A continuous myofibroblast precursor cell line from the tail muscle of Australasian snapper (Chrysophrys auratus) that responds to transforming growth factor beta and fibroblast growth factor, 2022, In Vitro Cellular & Developmental Biology - Animal
  • VHSV IVb infection and autophagy modulation in the rainbow trout gill epithelial cell line RTgill-W1, 2020, Journal of Fish Diseases
  • Xela DS2 and Xela VS2: Two novel skin epithelial-like cell lines from adult African clawed frog (Xenopus laevis) and their response to an extracellular viral dsRNA analogue, 2020, Developmental & Comparative Immunology

Frequent co-authors collaborating with Bols include:

  • Lucy E. J. Lee
  • Georgina C. Dowd
  • Vivian R. Dayeh
  • Phuc H. Pham
  • John S. Lumsden

Best Publications

  • Ecotoxicology and innate immunity in fish

    Niels C Bols;John L Brubacher;Rosemarie C Ganassin;Lucila E.J Lee

  • Identification and Bioactivities of IFN-γ in Rainbow Trout Oncorhynchus mykiss: The First Th1-Type Cytokine Characterized Functionally in Fish

    Jun Zou;Allison Carrington;Bertrand Collet;Johannes Martinus Dijkstra

  • Development and characterization of a rainbow trout liver cell line expressing cytochrome P450-dependent monooxygenase activity.

    Lucila E. J. Lee;Janine H. Clemons;Daniel G. Bechtel;Sarah J. Caldwell

  • Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor-alpha.

    Kerry J. Laing;Tiehui Wang;Jun Zou;Jason Holland

  • The use of fish cells in ecotoxicology. The report and recommendations of ECVAM Workshop 47.

    Argelia Castaño;Niels Bols;Thomas Braunbeck;Paul Dierickx

  • Development of a monocyte/macrophage-like cell line, RTS11, from rainbow trout spleen

    Rosemarie C. Ganassin;Niels C. Bols

  • Methodology for demonstrating and measuring the photocytotoxicity of fluoranthene to fish cells in culture

    K. Schirmer;A.G.J. Chan;B.M. Greenberg;D.G. Dixon

  • Development of a cell line from primary cultures of rainbow trout, Oncorhynchus mykiss (Walbaum), gills

    N. C. Bols;A. Barlian;M. Chirino-Trejo;S. J. Caldwell

  • Synthesis of polybrominated diphenyl ethers and their capacity to induce CYP1A by the Ah receptor mediated pathway.

    Guosheng Chen;Alexandre D. Konstantinov;Brock G. Chittim;Elizabeth M. Joyce

  • Chapter 2 Use of fish cell lines in the toxicology and ecotoxicology of fish. Piscine cell lines in environmental toxicology

    N.C. Bols;V.R. Dayeh;L.E.J. Lee;K. Schirmer

  • Ability of polycyclic aromatic hydrocarbons to induce 7-ethoxyresorufin-o-deethylase activity in a trout liver cell line.

    N.C. Bols;K. Schirmer;E.M. Joyce;D.G. Dixon

  • Production of zebrafish germ-line chimeras from embryo cell cultures

    Chunguang Ma;Lianchun Fan;Rosemarie Ganassin;Niels Bols

  • Functional characterisation of the recombinant tumor necrosis factors in rainbow trout, Oncorhynchus mykiss.

    Jun Zou;S Peddie;Giuseppe Scapigliati;Y Zhang

  • Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs)

    Sonya M. Billiard;Mark E. Hahn;Diana G. Franks;Richard E. Peterson

  • Identification and analysis of an interleukin 8-like molecule in rainbow trout Oncorhynchus mykiss

    Kerry J. Laing;Jun J. Zou;Tiehui Wang;Niels Bols

  • Ability of 16 priority PAHs to be directly cytotoxic to a cell line from the rainbow trout gill

    K Schirmer;D.G Dixon;B.M Greenberg;N.C Bols

  • The production and bioactivity of rainbow trout (Oncorhynchus mykiss) recombinant IL-1β

    Suhee Hong;Jun Zou;Mireille Crampe;Scott Peddie

  • Single and combined toxicity of pharmaceuticals and personal care products (PPCPs) on the rainbow trout liver cell line RTL-W1

    Sabine Schnell;Niels C. Bols;Carlos Barata;Cinta Porte

  • Technology and uses of cell cultures from the tissues and organs of bony fish

    N. C. Bols;L. E. J. Lee;L. E. J. Lee

  • Evaluating the toxicity of Triton X-100 to protozoan, fish, and mammalian cells using fluorescent dyes as indicators of cell viability

    Vivian R Dayeh;Stephanie L Chow;Kristin Schirmer;Denis H Lynn

Frequent Co-Authors

Kristin Schirmer
Kristin Schirmer Swiss Federal Institute of Aquatic Science and Technology
Christopher J. Secombes
Christopher J. Secombes University of Aberdeen
Peter V. Hodson
Peter V. Hodson Queen's University
Bruce M. Greenberg
Bruce M. Greenberg University of Waterloo
Denis H. Lynn
Denis H. Lynn University of British Columbia
D. George Dixon
D. George Dixon University of Waterloo
Helmut Segner
Helmut Segner University of Bern
M. Moo-Young
M. Moo-Young University of Waterloo
Tiehui Wang
Tiehui Wang University of Aberdeen
Keith R. Solomon
Keith R. Solomon University of Guelph

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