2026 Dae-Sik Lim: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	67	1553	1392	5	5	138	22302

Overview

Dae-Sik Lim is affiliated with the Korea Advanced Institute of Science and Technology in South Korea. Their research spans multiple fields, primarily within biochemistry, genetics, molecular biology, and medicine. Lim's contributions cover various subfields including cell biology, molecular biology, oncology, biochemistry, and epidemiology.

The main topics of Lim's research focus on the Hippo pathway signaling and YAP/TAZ, which make up the core of their work, with additional interests in Wnt/β-catenin signaling in development and cancer, ubiquitin and proteasome pathways, lipid metabolism and biosynthesis, adipose tissue and metabolism, extracellular vesicles in disease, and cancer cells and metastasis.

The scientist has published extensively in various journals. Frequent publication venues include:

Nature Communications
The EMBO Journal
Experimental & Molecular Medicine
eLife
bioRxiv (Cold Spring Harbor Laboratory)

Several recent papers by Lim illustrate their research interests and contributions:

Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi, 2020, Nature Communications
YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells, 2020, Nature Communications
YAP and AP-1 Cooperate to Initiate Pancreatic Cancer Development from Ductal Cells in Mice, 2020, Cancer Research
Two Hippo signaling modules orchestrate liver size and tumorigenesis, 2023, The EMBO Journal
The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis, 2021, Nature Communications

Frequent collaborators in Lim's work include:

David Eisenbarth
Bomin Ku
Ju-Gyeong Kang
Jae Myoung Suh
Daehee Hwang

Best Publications

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Christine E. Canman;Dae Sik Lim;Karlene A. Cimprich;Yoichi Taya

2672
Citations
Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

Shyam K. Sharan;Masami Morimatsu;Masami Morimatsu;Urs Albrecht;Dae Sik Lim

1384
Citations
Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members

Seong Tae Kim;Dae Sik Lim;Christine E. Canman;Michael B. Kastan

1070
Citations
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

Dae-Sik Lim;Seong-Tae Kim;Bo Xu;Richard S. Maser

1016
Citations
The many substrates and functions of ATM.

Michael B. Kastan;Dae-sik Lim

1001
Citations
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53.

Dae Sik Lim;Paul Hasty

893
Citations
Caspase-3-dependent Cleavage of Bcl-2 Promotes Release of Cytochrome c

David G. Kirsch;Andrea Doseff;B. Nelson Chau;Dae-Sik Lim

652
Citations
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.

Bo Xu;Seong-Tae Kim;Dae-Sik Lim;Michael B. Kastan

638
Citations
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

Jung Soon Mo;Zhipeng Meng;Young Chul Kim;Hyun Woo Park

540
Citations
The Hippo–Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis

Kwang-Pyo Lee;Joo-Hyeon Lee;Tae-Shin Kim;Tack-Hoon Kim

536
Citations
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

Chengming Zhu;Molly A. Bogue;Dae Sik Lim;Paul Hasty

521
Citations
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

Yasuhiro Maejima;Yasuhiro Maejima;Shiori Kyoi;Peiyong Zhai;Tong Liu

503
Citations
Deletion of Ku86 causes early onset of senescence in mice.

Hannes Vogel;Dae Sik Lim;Gerard Karsenty;Milton Finegold

433
Citations
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC–Cdc20 complex

Min Sup Song;Min Sup Song;Su Jeong Song;Nagi G. Ayad;Jin Sook Chang

416
Citations
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.

Dongjun Lee;Changwon Park;Ho Lee;Jesse J. Lugus

354
Citations
YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

Jongshin Kim;Yoo Hyung Kim;Jaeryung Kim;Do Young Park

338
Citations
Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

Minchul Kim;Taekhoon Kim;Randy L. Johnson;Dae Sik Lim

334
Citations
Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development

Antoine Reginensi;Rizaldy P. Scott;Alex Gregorieff;Mazdak Bagherie-Lachidan;Mazdak Bagherie-Lachidan

290
Citations
A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response

Dan Shao;Peiyong Zhai;Dominic P. Del Re;Sebastiano Sciarretta

257
Citations
The role of ATM in DNA damage responses and cancer

Christine E. Canman;Dae Sik Lim

244
Citations

Frequent Co-Authors

Michael B. Kastan Duke University

Jin-Man Kim Seoul National University

Paul Hasty The University of Texas Health Science Center at San Antonio

Eui Ju Choi Korea University

Gou Young Koh Korea Advanced Institute of Science and Technology

Young-Yun Kong Seoul National University

Bon-Kyoung Koo Austrian Academy of Sciences

Won Do Heo Korea Advanced Institute of Science and Technology

Randy L. Johnson The University of Texas MD Anderson Cancer Center

Junichi Sadoshima Rutgers, The State University of New Jersey

External Links

Personal website of Dae-Sik Lim

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