Won Do Heo mainly investigates Cell biology, Intracellular, GTPase, Peptide sequence and Biochemistry. His research links Optogenetics with Cell biology. His work in Intracellular covers topics such as In vivo which are related to areas like Transduction, HEK 293 cells, Cytosol and Protein–protein interaction.
His work carried out in the field of GTPase brings together such families of science as Endocytic cycle, PAK1 and Vacuole. His biological study spans a wide range of topics, including Protein structure, Plasma protein binding, Pleckstrin homology domain and Phosphatidylinositol 3-Kinases. His STIM2 study integrates concerns from other disciplines, such as Small interfering RNA, Suppressor, Stromal cell and Tumor growth.
Won Do Heo mainly focuses on Cell biology, Optogenetics, Signal transduction, Biochemistry and Fusion protein. His Cell biology research focuses on subjects like Receptor, which are linked to Kinase. The various areas that Won Do Heo examines in his Optogenetics study include Skull, Wavefront, Optics, Cell migration and Endogeny.
As a member of one scientific family, he mostly works in the field of Signal transduction, focusing on Regulation of gene expression and, on occasion, Systemic acquired resistance and Transgene. As a part of the same scientific family, Won Do Heo mostly works in the field of Fusion protein, focusing on Biophysics and, on occasion, Transmembrane domain, Calcium, STIM1, Immunoprecipitation and Function. His Peptide sequence study incorporates themes from Pleckstrin homology domain, Phosphatidylinositol, Phosphatidylinositol 3-Kinases and Caenorhabditis elegans.
Won Do Heo spends much of his time researching Cell biology, Optogenetics, Neuroscience, Endogeny and Intracellular. His Cell biology study frequently draws connections between adjacent fields such as Receptor. The study incorporates disciplines such as Computational biology, Function, HEK 293 cells, Signal transduction and Ribosome in addition to Optogenetics.
His work on Hippocampus, Neurogenesis and Dystonia as part of general Neuroscience study is frequently linked to Dorsal raphe nucleus and Deep cerebellar nuclei, bridging the gap between disciplines. His Endogeny research incorporates themes from Stimulation and Functional anatomy. The concepts of his Intracellular study are interwoven with issues in Cytoplasm, N-linked glycosylation, Hepatocyte, Golgi apparatus and Rab.
His scientific interests lie mostly in Optogenetics, Cell biology, HEK 293 cells, Signal transduction and Endogeny. His Optogenetics research is multidisciplinary, incorporating perspectives in Protein biosynthesis, Translation, Messenger RNA, Motility and Gene silencing. His studies in Cell biology integrate themes in fields like Cell migration, Antibody and Adrenergic.
Won Do Heo combines subjects such as Excitatory postsynaptic potential, Gene expression, Stimulation and Ca2 channels with his study of HEK 293 cells. His study in the field of CDC42 and Small GTPase is also linked to topics like Stereotaxic technique. His Endogeny research incorporates elements of Receptor, Gelsolin, Neuroscience and Intracellular.
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STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx
Jen Liou;Man Lyang Kim;Won Do Heo;Joshua T. Jones.
Current Biology (2005)
STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx
Jen Liou;Won Do Heo;Joshua T. Jones;Jason W. Myers.
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane.
Won Do Heo;Takanari Inoue;Wei Sun Park;Man Lyang Kim.
An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways
Takanari Inoue;Won Do Heo;Joshua S Grimley;Thomas J Wandless.
Nature Methods (2005)
Involvement of specific calmodulin isoforms in salicylic acid-independent activation of plant disease resistance responses
Won Do Heo;Sang Hyoung Lee;Min Chul Kim;Jong Cheol Kim.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Direct Interaction of a Divergent CaM Isoform and the Transcription Factor, MYB2, Enhances Salt Tolerance in Arabidopsis
Jae Hyuk Yoo;Chan Young Park;Jong Cheol Kim;Won Do Heo.
Journal of Biological Chemistry (2005)
Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
Nambin Yim;Seung Wook Ryu;Kyungsun Choi;Kwang Ryeol Lee.
Nature Communications (2016)
A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium
Adam C. Smith;Won Do Heo;Virginie Braun;Xiuju Jiang.
Journal of Cell Biology (2007)
Comprehensive identification of PIP3-regulated PH domains from C elegans to H sapiens by model prediction and live imaging
Wei Sun Park;Won Do Heo;Won Do Heo;James H. Whalen;Nancy A. O'Rourke.
Molecular Cell (2008)
Reversible protein inactivation by optogenetic trapping in cells
Sangkyu Lee;Hye Rim Park;Taeyoon Kyung;Na Yeon Kim.
Nature Methods (2014)
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