D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 42 Citations 11,055 93 World Ranking 15388 National Ranking 152

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Won Do Heo mainly investigates Cell biology, Intracellular, GTPase, Peptide sequence and Biochemistry. His research links Optogenetics with Cell biology. His work in Intracellular covers topics such as In vivo which are related to areas like Transduction, HEK 293 cells, Cytosol and Protein–protein interaction.

His work carried out in the field of GTPase brings together such families of science as Endocytic cycle, PAK1 and Vacuole. His biological study spans a wide range of topics, including Protein structure, Plasma protein binding, Pleckstrin homology domain and Phosphatidylinositol 3-Kinases. His STIM2 study integrates concerns from other disciplines, such as Small interfering RNA, Suppressor, Stromal cell and Tumor growth.

His most cited work include:

  • STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx (1688 citations)
  • PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. (621 citations)
  • STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx (341 citations)

What are the main themes of his work throughout his whole career to date?

Won Do Heo mainly focuses on Cell biology, Optogenetics, Signal transduction, Biochemistry and Fusion protein. His Cell biology research focuses on subjects like Receptor, which are linked to Kinase. The various areas that Won Do Heo examines in his Optogenetics study include Skull, Wavefront, Optics, Cell migration and Endogeny.

As a member of one scientific family, he mostly works in the field of Signal transduction, focusing on Regulation of gene expression and, on occasion, Systemic acquired resistance and Transgene. As a part of the same scientific family, Won Do Heo mostly works in the field of Fusion protein, focusing on Biophysics and, on occasion, Transmembrane domain, Calcium, STIM1, Immunoprecipitation and Function. His Peptide sequence study incorporates themes from Pleckstrin homology domain, Phosphatidylinositol, Phosphatidylinositol 3-Kinases and Caenorhabditis elegans.

He most often published in these fields:

  • Cell biology (58.87%)
  • Optogenetics (19.35%)
  • Signal transduction (16.94%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (58.87%)
  • Optogenetics (19.35%)
  • Neuroscience (4.84%)

In recent papers he was focusing on the following fields of study:

Won Do Heo spends much of his time researching Cell biology, Optogenetics, Neuroscience, Endogeny and Intracellular. His Cell biology study frequently draws connections between adjacent fields such as Receptor. The study incorporates disciplines such as Computational biology, Function, HEK 293 cells, Signal transduction and Ribosome in addition to Optogenetics.

His work on Hippocampus, Neurogenesis and Dystonia as part of general Neuroscience study is frequently linked to Dorsal raphe nucleus and Deep cerebellar nuclei, bridging the gap between disciplines. His Endogeny research incorporates themes from Stimulation and Functional anatomy. The concepts of his Intracellular study are interwoven with issues in Cytoplasm, N-linked glycosylation, Hepatocyte, Golgi apparatus and Rab.

Between 2018 and 2021, his most popular works were:

  • Optogenetic activation of intracellular antibodies for direct modulation of endogenous proteins. (39 citations)
  • Optogenetic control of mRNA localization and translation in live cells (23 citations)
  • Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His scientific interests lie mostly in Optogenetics, Cell biology, HEK 293 cells, Signal transduction and Endogeny. His Optogenetics research is multidisciplinary, incorporating perspectives in Protein biosynthesis, Translation, Messenger RNA, Motility and Gene silencing. His studies in Cell biology integrate themes in fields like Cell migration, Antibody and Adrenergic.

Won Do Heo combines subjects such as Excitatory postsynaptic potential, Gene expression, Stimulation and Ca2 channels with his study of HEK 293 cells. His study in the field of CDC42 and Small GTPase is also linked to topics like Stereotaxic technique. His Endogeny research incorporates elements of Receptor, Gelsolin, Neuroscience and Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou;Man Lyang Kim;Won Do Heo;Joshua T. Jones.
Current Biology (2005)

2249 Citations

STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx

Jen Liou;Won Do Heo;Joshua T. Jones;Jason W. Myers.
(2005)

2240 Citations

PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane.

Won Do Heo;Takanari Inoue;Wei Sun Park;Man Lyang Kim.
Science (2006)

775 Citations

An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways

Takanari Inoue;Won Do Heo;Joshua S Grimley;Thomas J Wandless.
Nature Methods (2005)

373 Citations

Involvement of specific calmodulin isoforms in salicylic acid-independent activation of plant disease resistance responses

Won Do Heo;Sang Hyoung Lee;Min Chul Kim;Jong Cheol Kim.
Proceedings of the National Academy of Sciences of the United States of America (1999)

288 Citations

Direct Interaction of a Divergent CaM Isoform and the Transcription Factor, MYB2, Enhances Salt Tolerance in Arabidopsis

Jae Hyuk Yoo;Chan Young Park;Jong Cheol Kim;Won Do Heo.
Journal of Biological Chemistry (2005)

272 Citations

Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module

Nambin Yim;Seung Wook Ryu;Kyungsun Choi;Kwang Ryeol Lee.
Nature Communications (2016)

266 Citations

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium

Adam C. Smith;Won Do Heo;Virginie Braun;Xiuju Jiang.
Journal of Cell Biology (2007)

185 Citations

Comprehensive identification of PIP3-regulated PH domains from C elegans to H sapiens by model prediction and live imaging

Wei Sun Park;Won Do Heo;Won Do Heo;James H. Whalen;Nancy A. O'Rourke.
Molecular Cell (2008)

173 Citations

Reversible protein inactivation by optogenetic trapping in cells

Sangkyu Lee;Hye Rim Park;Taeyoon Kyung;Na Yeon Kim.
Nature Methods (2014)

171 Citations

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