World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
14478
World Ranking
16486
National Ranking
197

Overview

Won Do Heo is affiliated with the Korea Advanced Institute of Science and Technology in South Korea. Their research primarily covers topics within biochemistry, genetics, molecular biology, and neuroscience. The focus spans multiple subfields including molecular biology, cellular and molecular neuroscience, biophysics, cognitive neuroscience, and atomic and molecular physics and optics.

The scientist's work addresses several main topics which include:

  • Photoreceptor and optogenetics research
  • Neuroscience and neuropharmacology research
  • Advanced fluorescence microscopy techniques
  • Digital holography and microscopy
  • Memory and neural mechanisms
  • Neuroscience and neural engineering
  • Light effects on plants

Frequent coauthors collaborating with Won Do Heo include:

  • YongKeun Park
  • Jinsu Lee
  • Wei Sun Park
  • Moosung Lee
  • Sangkyu Lee

Their research has been published in several notable scientific venues. The most frequent publication venues are:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Molecular Brain
  • Nature Cell Biology

Selected papers by Won Do Heo include:

  • Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning, 2021, Nature Cell Biology
  • CCR5 closes the temporal window for memory linking, 2022, Nature
  • Non-invasive optical control of endogenous Ca2+ channels in awake mice, 2020, Nature Communications
  • Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy, 2020, Nature Communications
  • Optogenetic control of mRNA localization and translation in live cells, 2020, Nature Cell Biology

Best Publications

  • STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

    Jen Liou;Man Lyang Kim;Won Do Heo;Joshua T. Jones

  • STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx

    Jen Liou;Won Do Heo;Joshua T. Jones;Jason W. Myers

  • PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane.

    Won Do Heo;Takanari Inoue;Wei Sun Park;Man Lyang Kim

  • Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module

    Nambin Yim;Seung Wook Ryu;Kyungsun Choi;Kwang Ryeol Lee

  • An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways

    Takanari Inoue;Won Do Heo;Joshua S Grimley;Thomas J Wandless

  • Direct Interaction of a Divergent CaM Isoform and the Transcription Factor, MYB2, Enhances Salt Tolerance in Arabidopsis

    Jae Hyuk Yoo;Chan Young Park;Jong Cheol Kim;Won Do Heo

  • Involvement of specific calmodulin isoforms in salicylic acid-independent activation of plant disease resistance responses

    Won Do Heo;Sang Hyoung Lee;Min Chul Kim;Jong Cheol Kim

  • Reversible protein inactivation by optogenetic trapping in cells

    Sangkyu Lee;Hye Rim Park;Taeyoon Kyung;Na Yeon Kim

  • Cooperative activation of PI3K by Ras and Rho family small GTPases.

    Hee Won Yang;Min-Gyoung Shin;Sangkyu Lee;Jeong-Rae Kim;Jeong-Rae Kim

  • A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium

    Adam C. Smith;Won Do Heo;Virginie Braun;Xiuju Jiang

  • The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole.

    Malina A. Bakowski;Virginie Braun;Grace Y. Lam;Tony Yeung

  • Identification of a Novel Divergent Calmodulin Isoform from Soybean Which Has Differential Ability to Activate Calmodulin-dependent Enzymes

    Sang Hyoung Lee;Jong Cheol Kim;Mal Soon Lee;Won Do Heo

  • Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking

    Jongshin Kim;Haiin Jo;Hyowon Hong;Min Hwan Kim

  • Comprehensive identification of PIP3-regulated PH domains from C elegans to H sapiens by model prediction and live imaging

    Wei Sun Park;Won Do Heo;Won Do Heo;James H. Whalen;Nancy A. O'Rourke

  • Spatiotemporal Control of Fibroblast Growth Factor Receptor Signals by Blue Light

    Nury Kim;Jin Man Kim;Minji Lee;Cha Yeon Kim

  • Optogenetic control of endogenous Ca 2+ channels in vivo

    Taeyoon Kyung;Sangkyu Lee;Jung Eun Kim;Taesup Cho

  • Overview of the Alliance for Cellular Signaling.

    Alfred G. Gilman;Melvin I. Simon;Henry R. Bourne;Bruce A. Harris

  • Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling

    Ki Young Chang;Doyeon Woo;Hyunjin Jung;Sangkyu Lee

  • Identification of a Calmodulin-Regulated Soybean Ca2+-ATPase (SCA1) That Is Located in the Plasma Membrane

    Woo Sik Chung;Sang Hyoung Lee;Jong Cheol Kim;Won Do Heo

  • Switch-of-Function Mutants Based on Morphology Classification of Ras Superfamily Small GTPases

    Won Do Heo;Tobias Meyer

Frequent Co-Authors

Tobias Meyer
Tobias Meyer Stanford University
Chulhee Choi
Chulhee Choi Korea Advanced Institute of Science and Technology
Moo Je Cho
Moo Je Cho Gyeongsang National University
Woo Sik Chung
Woo Sik Chung Gyeongsang National University
Min Chul Kim
Min Chul Kim Gyeongsang National University
John H. Brumell
John H. Brumell University of Toronto
Eunjoon Kim
Eunjoon Kim Korea Advanced Institute of Science and Technology
Kwang-Hyun Cho
Kwang-Hyun Cho Korea Advanced Institute of Science and Technology
Morgan Sheng
Morgan Sheng Broad Institute
Daesoo Kim
Daesoo Kim Korea Advanced Institute of Science and Technology

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