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Sergio Grinstein
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Biology and Biochemistry
Canada
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
149
Citations
80939
World Ranking
189
National Ranking
6

Sergio Grinstein publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Sergio Grinstein sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 711 publications — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Sergio Grinstein D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sergio Grinstein sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 149 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2025 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2022 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2000 - Fellow of the Royal Society of Canada Academy of Science

Overview

Sergio Grinstein is affiliated with the Hospital for Sick Children in Canada. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on cellular and immune processes.

The main fields of study for Grinstein include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields cover various aspects of cell and immune biology:

  • Molecular Biology
  • Immunology
  • Cell Biology
  • Physiology
  • Surgery

Grinstein's work prominently addresses several research topics including:

  • Cellular transport and secretion
  • Erythrocyte Function and Pathophysiology
  • Phagocytosis and Immune Regulation
  • Calcium signaling and nucleotide metabolism
  • Lipid Membrane Structure and Behavior
  • Pancreatic function and diabetes
  • Cell Adhesion Molecules Research

The scientist has co-authored publications frequently with colleagues such as Spencer A. Freeman, Michelle E. Maxson, Johannes Westman, Glenn F. W. Walpole, and Jonathan Plumb.

Grinstein has contributed to a variety of journals and publication venues, with frequent appearances in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • The Journal of Cell Biology
  • Current Biology

Notable recent papers include:

  • The cytoskeleton in phagocytosis and macropinocytosis, 2021, Current Biology
  • Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis, 2023, Current Biology
  • Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation, 2020, Frontiers in Immunology
  • Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection, 2020, Cell Host & Microbe
  • Determinants, maintenance, and function of organellar pH, 2022, Physiological Reviews

Grinstein was awarded the title of Fellow of the Royal Society of Canada in 2000, recognized by the Academy of Science. This affiliation marks a notable aspect of their career.

Best Publications

  • Sensors and regulators of intracellular pH

    Joseph R. Casey;Sergio Grinstein;John Orlowski

  • Robust single-particle tracking in live-cell time-lapse sequences.

    Khuloud Jaqaman;Dinah Loerke;Marcel Mettlen;Hirotaka Kuwata

  • Membrane phosphatidylserine regulates surface charge and protein localization

    Tony Yeung;Gary E. Gilbert;Jialan Shi;John Silvius

  • The Cell Biology of Phagocytosis

    Ronald S. Flannagan;Valentin Jaumouillé;Sergio Grinstein

  • Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

    Ronald S. Flannagan;Gabriela Cosío;Sergio Grinstein

  • The distribution and function of phosphatidylserine in cellular membranes.

    Peter A Leventis;Sergio Grinstein

  • Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation.

    Sergio Grinstein;Daniela Rotin;Michael J. Mason

  • Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

    Mirkka Koivusalo;Christopher Welch;Hisayoshi Hayashi;Cameron C Scott

  • Phagocytosis and innate immunity.

    Steven Greenberg;Sergio Grinstein

  • Scavenger receptors in homeostasis and immunity

    Johnathan Canton;Dante Neculai;Sergio Grinstein;Sergio Grinstein

  • Mechanisms of regulation of the Na+/H+ exchanger

    Sergio Grinstein;Ase Rothstein

  • Phagosome maturation: aging gracefully.

    Otilia V. Vieira;Roberto J. Botelho;Sergio Grinstein

  • The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

    Koichi Tabeta;Kasper Hoebe;Edith M. Janssen;Xin Du

  • Diversity of the mammalian sodium/proton exchanger SLC9 gene family.

    John Orlowski;Sergio Grinstein

  • LAMP proteins are required for fusion of lysosomes with phagosomes.

    Kassidy K Huynh;Eeva-Liisa Eskelinen;Cameron C Scott;Anatoly Malevanets

  • The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange.

    Randy A. Hall;Richard T. Premont;Chung-Wai Chow;Jeremy T. Blitzer

  • Na+/H+ Exchangers of Mammalian Cells *

    John Orlowski;Sergio Grinstein

  • Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis

    Roberto J. Botelho;Mary Teruel;Renee Dierckman;Richard Anderson

  • Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

    Otilia V. Vieira;Otilia V. Vieira;Roberto J. Botelho;Lucia Rameh;Saskia M. Brachmann;Saskia M. Brachmann

  • Activation of antibacterial autophagy by NADPH oxidases

    Ju Huang;Veronica Canadien;Grace Y. Lam;Benjamin E. Steinberg

Frequent Co-Authors

Gregory P. Downey
Gregory P. Downey National Jewish Health
John H. Brumell
John H. Brumell University of Toronto
John Orlowski
John Orlowski McGill University
Ori D. Rotstein
Ori D. Rotstein University of Toronto
William S. Trimble
William S. Trimble University of Toronto
Richard F. Collins
Richard F. Collins University of Manchester
Aser Rothstein
Aser Rothstein University of Rochester
Alan D. Schreiber
Alan D. Schreiber University of Pennsylvania
Andras Kapus
Andras Kapus University of Toronto
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University

External Links

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Best Scientists Citing Sergio Grinstein

Mark Donowitz

Mark Donowitz

Johns Hopkins University School of Medicine

Publications: 82

Larry Fliegel

Larry Fliegel

University of Alberta

Publications: 80

Thomas E. DeCoursey

Thomas E. DeCoursey

Rush University

Publications: 66

Florian Lang

Florian Lang

University of Tübingen

Publications: 63

Pascale Cossart

Pascale Cossart

Institut Pasteur

Publications: 61

Stine F. Pedersen

Stine F. Pedersen

University of Copenhagen

Publications: 55

Philippe Gros

Philippe Gros

McGill University

Publications: 55

John H. Brumell

John H. Brumell

University of Toronto

Publications: 52

Nicolas Demaurex

Nicolas Demaurex

University of Geneva

Publications: 50

Edward J. Weinman

Edward J. Weinman

University of Maryland, Baltimore

Publications: 49

Else K. Hoffmann

Else K. Hoffmann

University of Copenhagen

Publications: 49

Gaudenz Danuser

Gaudenz Danuser

The University of Texas Southwestern Medical Center

Publications: 48

Kirsten Sandvig

Kirsten Sandvig

Oslo University Hospital

Publications: 47

C. Chris Yun

C. Chris Yun

Emory University

Publications: 47

Gergely L. Lukacs

Gergely L. Lukacs

McGill University

Publications: 46

Harald Alfred Stenmark

Harald Alfred Stenmark

University of Oslo

Publications: 46

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