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Gergely L. Lukacs

Gergely L. Lukacs

McGill University
Canada

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
19779
World Ranking
5324
National Ranking
197

Gergely L. Lukacs publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Gergely L. Lukacs sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 186 publications — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Gergely L. Lukacs D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Gergely L. Lukacs sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 75 D-Index — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Gergely L. Lukacs is affiliated with McGill University in Canada and has a research portfolio primarily focused on biochemistry, genetics, and molecular biology as well as medicine.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, they have contributed substantially to several subfields of study, such as:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cell Biology
  • Physiology
  • Infectious Diseases

Their research focuses on diverse topics within molecular and cellular biology, with a particular emphasis on cystic fibrosis and related cellular mechanisms. Key research areas include:

  • Cystic Fibrosis Research Advances
  • Cellular transport and secretion
  • RNA and protein synthesis mechanisms
  • Calcium signaling and nucleotide metabolism
  • Advanced biosensing and bioanalysis techniques
  • Endoplasmic Reticulum Stress and Disease
  • Drug Transport and Resistance Mechanisms

Lukacs has published extensively, with multiple articles in high-impact and specialized journals. Frequent publication venues for their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cystic Fibrosis
  • Cellular and Molecular Life Sciences
  • Scientific Reports
  • UNC Libraries

Among their recent papers are:

  • "Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination," 2020, JCI Insight
  • "Ins and outs of AlphaFold2 transmembrane protein structure predictions," 2022, Cellular and Molecular Life Sciences
  • "Elexacaftor co-potentiates the activity of F508del and gating mutants of CFTR," 2021, Journal of Cystic Fibrosis
  • "Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex," 2021, Molecular Cell
  • "Analysis of AlphaMissense data in different protein groups and structural context," 2024, Scientific Data

Collaboration is an important aspect of their work, with frequent co-authors including:

  • Tamás Hegedűs
  • Guido Veit
  • Haijin Xu
  • Naoto Soya
  • Ariel Roldán

Best Publications

  • Size-dependent DNA Mobility in Cytoplasm and Nucleus

    Gergely L Lukacs;Peter Haggie;Olivier Seksek;Delphine Lechardeur

  • Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer.

    Delphine Lechardeur;K. J. Sohn;M. Haardt;P. B. Joshi

  • Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

    Marie E. Egan;Marilyn Pearson;Scott A. Weiner;Vanathy Rajendran

  • Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening

    Nicoletta Pedemonte;Gergely L. Lukacs;Kai Du;Emanuela Caci

  • From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

    Gudio Veit;Radu G. Avramescu;Annette N. Chiang;Scott A. Houck

  • Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.

    Gergely L. Lukacs;Abdalla Mohamed;Norbert Kartner;Xu Bao Chang

  • Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane

    Tsukasa Okiyoneda;Hervé Barrière;Miklós Bagdány;Wael M. Rabeh

  • Mechanism-based corrector combination restores ΔF508-CFTR folding and function

    Tsukasa Okiyoneda;Guido Veit;Johanna F Dekkers;Miklos Bagdany

  • The ΔF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR

    Kai Du;Manu Sharma;Gergely L Lukacs

  • Intracellular routing of plasmid DNA during non-viral gene transfer

    Delphine Lechardeur;A S Verkman;Gergely L Lukacs

  • CFTR: folding, misfolding and correcting the ΔF508 conformational defect

    Gergely L. Lukacs;A.S. Verkman

  • Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function

    Wael M. Rabeh;Florian Bossard;Haijin Xu;Tsukasa Okiyoneda

  • Misfolding diverts CFTR from recycling to degradation quality control at early endosomes

    Manu Sharma;Francesca Pampinella;Csilla Nemes;Mohamed Benharouga

  • The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

    Gergely L. Lukacs;Xiu Bao Chang;Christine Bear;Norbert Kartner

  • Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression

    Guido Veit;Radu G. Avramescu;Doranda Perdomo;Puay Wah Phuan

  • Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

    Darren M Hutt;David Herman;Ana P C Rodrigues;Sabrina Noel

  • Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages.

    G L Lukacs;O D Rotstein;S Grinstein

  • Intracellular barriers to non-viral gene transfer.

    Delphine Lechardeur;Gergely L Lukacs

  • C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation.

    Martin Haardt;Mohamed Benharouga;Delphine Lechardeur;Norbert Kartner

  • Conformational and Temperature-sensitive Stability Defects of the ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator in Post-endoplasmic Reticulum Compartments

    Manu Sharma;Mohamed Benharouga;Wei Hu;Gergely L. Lukacs

Frequent Co-Authors

Alan S. Verkman
Alan S. Verkman University of California, San Francisco
Eric J. Sorscher
Eric J. Sorscher Emory University
Raymond A. Frizzell
Raymond A. Frizzell University of Pittsburgh
Aleksander Edelman
Aleksander Edelman Université Paris Cité
John R. Riordan
John R. Riordan University of North Carolina at Chapel Hill
Luis J. V. Galietta
Luis J. V. Galietta Telethon Institute Of Genetics And Medicine
Manu Sharma
Manu Sharma University of Tübingen
William E. Balch
William E. Balch Scripps Health
Walter E. Finkbeiner
Walter E. Finkbeiner University of California, San Francisco
Dale J. Benos
Dale J. Benos University of Alabama at Birmingham

External Links

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