D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 18,853 107 World Ranking 8189 National Ranking 599

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Mutation

The scientist’s investigation covers issues in Genome-wide association study, Genetics, Meta-analysis, Single-nucleotide polymorphism and Odds ratio. He has researched Genome-wide association study in several fields, including Genetic heterogeneity, Genetic association, Allele frequency and Risk factor. His Folding research extends to the thematically linked field of Genetics.

His Odds ratio research includes elements of Case-control study and Parkinson's disease. His work carried out in the field of Case-control study brings together such families of science as Ashkenazi jews, Genotyping and Gene mutation. He interconnects Glucocerebrosidase, Computational biology and Genotype in the investigation of issues within Parkinson's disease.

His most cited work include:

  • Genome-wide association study reveals genetic risk underlying Parkinson's disease (1433 citations)
  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease (1232 citations)
  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease (1232 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Genetics, Genome-wide association study, Parkinson's disease, Genetic association and Single-nucleotide polymorphism. His research investigates the connection between Genetics and topics such as Disease that intersect with problems in Genetic architecture. The Genome-wide association study study combines topics in areas such as Minor allele frequency, Allele frequency, Meta-analysis, Age of onset and Genetic variation.

His Parkinson's disease study integrates concerns from other disciplines, such as Glucocerebrosidase, Family history and Bioinformatics. His studies in Single-nucleotide polymorphism integrate themes in fields like Odds ratio, Molecular genetics and Quantitative trait locus. His Odds ratio research incorporates elements of Case-control study and Genetic epidemiology.

He most often published in these fields:

  • Genetics (53.39%)
  • Genome-wide association study (38.14%)
  • Parkinson's disease (27.97%)

What were the highlights of his more recent work (between 2018-2021)?

  • Genetics (53.39%)
  • Disease (22.03%)
  • Genetic association (27.12%)

In recent papers he was focusing on the following fields of study:

Manu Sharma spends much of his time researching Genetics, Disease, Genetic association, Parkinson's disease and Genome-wide association study. His work on Allele, Gene and Transmission disequilibrium test as part of general Genetics study is frequently linked to Context, bridging the gap between disciplines. In Disease, Manu Sharma works on issues like Genetic architecture, which are connected to Comorbidity.

His Genetic association research focuses on Locus and how it connects with Risk factor, Cohort, Movement disorders and False discovery rate. His Parkinson's disease research integrates issues from Glucocerebrosidase, Dementia and Mitochondrion. His Genome-wide association study study incorporates themes from Age of onset, Genetic variation and Heritability.

Between 2018 and 2021, his most popular works were:

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies (353 citations)
  • Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms. (108 citations)
  • Expanding Parkinson’s disease genetics: novel risk loci, genomic context, causal insights and heritable risk (78 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Mutation

Manu Sharma mostly deals with Genetics, Disease, Parkinson's disease, Genome-wide association study and Context. His research in Disease intersects with topics in Pathological and Single-nucleotide polymorphism. Manu Sharma interconnects Meta-analysis, Mendelian inheritance and Genetic architecture in the investigation of issues within Single-nucleotide polymorphism.

His biological study spans a wide range of topics, including Calcium metabolism, Calcium, Transition, Phenotype and Mitochondrion. His Genome-wide association study research is multidisciplinary, incorporating perspectives in Genetic association and Age of onset. The Genetic association study combines topics in areas such as Genetic variability, Genetic variation, Allele and Heritability.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genome-wide association study reveals genetic risk underlying Parkinson's disease

Javier Simón-Sánchez;Claudia Schulte;Jose M Bras;Jose M Bras;Manu Sharma.
Nature Genetics (2009)

1970 Citations

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz.
The New England Journal of Medicine (2009)

1845 Citations

α-Synuclein promotes SNARE-complex assembly in vivo and in vitro

Jacqueline Burre;Manu Sharma;Theodoros Tsetsenis;Vladimir L. Buchman.
Science (2010)

1442 Citations

Analysis of shared heritability in common disorders of the brain

Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters.
Science (2018)

1200 Citations

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.

Michael A Nalls;Vincent Plagnol;Dena G Hernandez.
The Lancet (2011)

925 Citations

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron.
Lancet Neurology (2019)

813 Citations

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

Mike A. Nalls;Nathan Pankratz;Christina M. Lill;Chuong B. Do.
PMC (2014)

612 Citations

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database.

Christina M. Lill;Johannes T. Roehr;Johannes T. Roehr;Matthew B. McQueen;Fotini K. Kavvoura;Fotini K. Kavvoura;Fotini K. Kavvoura.
PLOS Genetics (2012)

560 Citations

The ΔF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR

Kai Du;Manu Sharma;Gergely L Lukacs.
Nature Structural & Molecular Biology (2005)

365 Citations

Misfolding diverts CFTR from recycling to degradation quality control at early endosomes

Manu Sharma;Francesca Pampinella;Csilla Nemes;Mohamed Benharouga.
Journal of Cell Biology (2004)

360 Citations

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