World's Best Scientists 2026 revealed!
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Genetics
USA
2026

D-Index & Metrics

Genetics

D-Index
139
Citations
90419
World Ranking
186
National Ranking
96

Medicine

D-Index
141
Citations
91375
World Ranking
1599
National Ranking
933

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Genetics in United States Leader Award

Overview

Mike A. Nalls is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions particularly in Molecular Biology, Neurology, and Genetics. They have published extensively in these areas, covering topics such as Parkinson's Disease Mechanisms and Treatments, Genetic Associations and Epidemiology, Neurological Diseases and Metabolism, Bioinformatics and Genomic Networks, RNA Regulation and Disease, CRISPR and Genetic Engineering, and Lysosomal Storage Disorders Research.

Their recent publications demonstrate a focus on molecular and cellular mechanisms underlying neurological conditions. Key papers include:

  • "Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis," 2021, Nature Neuroscience
  • "Virus exposure and neurodegenerative disease risk across national biobanks," 2023, Neuron
  • "Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans," 2020, JAMA Neurology
  • "A reference human induced pluripotent stem cell line for large-scale collaborative studies," 2022, Cell Stem Cell
  • "A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states," 2022, Nature Neuroscience

Their collaborations include frequent coauthors such as Andrew Singleton, Cornelis Blauwendraat, Hampton L. Leonard, Sara Bandrés-Ciga, and Hirotaka Iwaki. These partnerships have contributed to advancing research in neurodegenerative diseases and genetic epidemiology.

Publication venues regularly featuring their research include bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, npj Parkinson's Disease, Movement Disorders, and Patterns. This indicates a consistent engagement with both preprint and peer-reviewed scientific communities related to neurology and molecular biology.

Best Publications

  • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

    Alan E. Renton;Elisa Majounie;Adrian James Waite;Javier Simón-Sánchez;Javier Simón-Sánchez

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

    Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Genome-wide association study reveals genetic risk underlying Parkinson's disease

    Javier Simón-Sánchez;Claudia Schulte;Jose M Bras;Jose M Bras;Manu Sharma

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

    Mike A Nalls;Nathan Pankratz;Christina M. Lill;Chuong B. Do

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Genome-wide analysis of genetic loci associated with Alzheimer disease.

    Sudha Seshadri;Annette L. Fitzpatrick;M Arfan Ikram;Anita L. DeStefano

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

    Elisa Majounie;Alan E. Renton;Kin Mok;Elise G. P. Dopper;Elise G. P. Dopper

  • A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.

    Diana Chang;Mike A Nalls;Ingileif B Hallgrímsdóttir;Julie Hunkapiller

  • Vitamin D–Binding Protein and Vitamin D Status of Black Americans and White Americans

    Camille E. Powe;Michele K. Evans;Julia Wenger;Alan B. Zonderman

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

    D I Swerdlow;M V Holmes;K B Kuchenbaecker

  • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

    Elizabeth K. Speliotes;Laura M. Yerges-Armstrong;Jun Wu;Ruben Hernaez;Ruben Hernaez

  • Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.

    Michael A Nalls;Vincent Plagnol;Dena G Hernandez

Frequent Co-Authors

Andrew B. Singleton
Andrew B. Singleton National Institutes of Health
Bruce M. Psaty
Bruce M. Psaty University of Washington
Dena G. Hernandez
Dena G. Hernandez National Institutes of Health
Tamara B. Harris
Tamara B. Harris National Institutes of Health
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
John Hardy
John Hardy University College London
Yongmei Liu
Yongmei Liu Duke University
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor

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