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Christine E. Bear

Christine E. Bear

University of Toronto
Canada

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12259
World Ranking
14358
National Ranking
502

Christine E. Bear publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christine E. Bear sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 195 publications — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christine E. Bear D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christine E. Bear sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 56 D-Index — 28th percentile

28% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christine E. Bear is affiliated with the University of Toronto in Canada and has contributed extensively to the field of Medicine, with a particular focus on Pulmonary and Respiratory Medicine. Their research portfolio includes work in Molecular Biology, Genetics, Physiology, and Biomedical Engineering, encompassing a total of 107 publications in the core field of Medicine.

The scientist's research topics cover several areas related to respiratory health and disease, with a strong emphasis on cystic fibrosis. Key topics of their work include:

  • Cystic Fibrosis Research Advances
  • Neonatal Respiratory Health Research
  • Tracheal and airway disorders
  • Renal and related cancers
  • Advanced biosensing and bioanalysis techniques
  • Asthma and respiratory diseases
  • Inhalation and Respiratory Drug Delivery

Christine E. Bear has coauthored many papers with frequent collaborators including Onofrio Laselva, Theo J. Moraes, Félix Ratjen, T. Gunawardena, and Tanja Gonska. The collaboration counts with these scholars range from 15 to 27 coauthored papers, demonstrating a consistent research partnership.

The scientist has published numerous papers in prominent journals. Frequent venues include:

  • Journal of Cystic Fibrosis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Respiratory Journal
  • Advanced Healthcare Materials
  • Journal of Personalized Medicine

Selected recent papers by Christine E. Bear and close collaborators include:

  • "Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator," 2020, European Respiratory Journal
  • "A Therapy for Most with Cystic Fibrosis," 2020, Cell
  • "Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator," 2021, iScience
  • "Clinical and functional efficacy of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis carrying the N1303K mutation," 2023, Journal of Cystic Fibrosis
  • "Generation of functional ciliated cholangiocytes from human pluripotent stem cells," 2021, Nature Communications

Best Publications

  • Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

    Christine E. Bear;Canhui Li;Norbert Kartner;Robert J. Bridges

  • Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

    Norbert Kartner;John W. Hanrahan;Tim J. Jensen;A. Leonard Naismith

  • Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

    Richard Rozmahel;Michael Wilschanski;Angabin Matin;Suzanne Plyte

  • Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein.

    Amy P Wong;Christine E Bear;Stephanie Chin;Peter Pasceri

  • ATPase Activity of the Cystic Fibrosis Transmembrane Conductance Regulator

    Canhui Li;Mohabir Ramjeesingh;Wei Wang;Elizabeth Garami

  • Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.

    Paul D.W. Eckford;Canhui Li;Mohabir Ramjeesingh;Christine E. Bear

  • The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

    Gergely L. Lukacs;Xiu Bao Chang;Christine Bear;Norbert Kartner

  • Directed differentiation of cholangiocytes from human pluripotent stem cells

    Mina Ogawa;Shinichiro Ogawa;Christine E Bear;Saumel Ahmadi

  • Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene.

    C E Bear;F Duguay;A L Naismith;N Kartner

  • The cystic fibrosis mutation (delta F508) does not influence the chloride channel activity of CFTR.

    Canhui Li;Mohabir Ramjeesingh;Evangelica Reyes;Tim Jensen

  • CFTR directly mediates nucleotide-regulated glutathione flux

    Ilana Kogan;Mohabir Ramjeesingh;Canhui Li;Jackie F. Kidd

  • LUNG DISEASE IN MICE WITH CYSTIC FIBROSIS

    G Kent;R Iles;C E Bear;L J Huan

  • Novel method for evaluation of the oligomeric structure of membrane proteins.

    Mohabir Ramjeesingh;Ling-Jun Huan;Elizabeth Garami;Christine E. Bear

  • Expression of the chloride channel ClC-2 in the murine small intestine epithelium.

    Katalin Gyömörey;Herman Yeger;Cameron Ackerley;Elizabeth Garami

  • Purified cystic fibrosis transmembrane conductance regulator (CFTR) does not function as an ATP channel.

    Canhui Li;Mohabir Ramjeesingh;Christine E. Bear

  • Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)

    Mohabir Ramjeesingh;Canhui Li;Elizabeth Garami;Ling-Jun Huan

  • Cystic fibrosis transmembrane conductance regulator in human muscle: Dysfunction causes abnormal metabolic recovery in exercise

    Anne-Marie Lamhonwah;Christine E Bear;Ling Jun Huan;Patrick Kim Chiaw

  • The chloride channel ClC-4 contributes to endosomal acidification and trafficking.

    Raha Mohammad-Panah;Rene Harrison;Sonja Dhani;Cameron Ackerley

  • Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator.

    Onofrio Laselva;Claire Bartlett;Tarini N.A. Gunawardena;Hong Ouyang

  • The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor

    Steven D. Broadbent;Steven D. Broadbent;Mohabir Ramjeesingh;Christine E. Bear;Barry E. Argent

Frequent Co-Authors

Johanna M. Rommens
Johanna M. Rommens University of Toronto
Gordon Keller
Gordon Keller University of Toronto
Herman Yeger
Herman Yeger University of Toronto
Cameron Ackerley
Cameron Ackerley University of Toronto
John R. Riordan
John R. Riordan University of North Carolina at Chapel Hill
Janet Rossant
Janet Rossant University of Toronto
Peter R. Durie
Peter R. Durie University of Toronto
Charles M. Deber
Charles M. Deber University of Toronto
Felix Ratjen
Felix Ratjen University of Toronto
Lap-Chee Tsui
Lap-Chee Tsui University of Toronto

External Links

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Best Scientists Citing Christine E. Bear

John R. Riordan

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University of North Carolina at Chapel Hill

Publications: 77

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John W. Hanrahan

McGill University

Publications: 60

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Michael J. Welsh

University of Iowa

Publications: 53

Margarida D. Amaral

Margarida D. Amaral

University of Lisbon

Publications: 46

Richard C. Boucher

Richard C. Boucher

University of North Carolina at Chapel Hill

Publications: 45

Frédéric Becq

Frédéric Becq

University of Poitiers

Publications: 44

Alan S. Verkman

Alan S. Verkman

University of California, San Francisco

Publications: 38

Karl Kunzelmann

Karl Kunzelmann

University of Regensburg

Publications: 38

Marcus A. Mall

Marcus A. Mall

Charité - University Medicine Berlin

Publications: 37

William B. Guggino

William B. Guggino

Johns Hopkins University

Publications: 36

Hugo R. de Jonge

Hugo R. de Jonge

Erasmus University Rotterdam

Publications: 34

Eric J. Sorscher

Eric J. Sorscher

Emory University

Publications: 32

Garry R. Cutting

Garry R. Cutting

Johns Hopkins University School of Medicine

Publications: 30

Thomas J. Jentsch

Thomas J. Jentsch

Charité - University Medicine Berlin

Publications: 30

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Aleksander Edelman

Université Paris Cité

Publications: 30

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Robert C. Ford

University of Manchester

Publications: 30

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