Lap-Chee Tsui

Research.com Recognitions

• 1991 - Fellow, The World Academy of Sciences
• 1991 - Fellow of the Royal Society, United Kingdom

Overview

Best Publications

• Identification of the cystic fibrosis gene: genetic analysis.

  Bat Sheva Kerem;Johanna M. Rommens;Janet A. Buchanan;Danuta Markiewicz

  5439
  Citations

• A second generation human haplotype map of over 3.1 million SNPs

  Kelly A. Frazer;Dennis G. Ballinger;David R. Cox;David A. Hinds

  5383
  Citations

• Germline and Somatic Mutations in the Tyrosine Kinase Domain of the MET Proto-Oncogene in Papillary Renal Carcinomas

  L. Schmidt;F.-M. Duh;F. Chen;T. Kishida

  1878
  Citations

• Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.

  Erich Roessler;Elena Belloni;Karin Gaudenz;Philippe Jay

  1327
  Citations

• Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.

  P. A. Marsden;H. H. Q. Heng;S. W. Scherer;R. J. Stewart

  1285
  Citations

• MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

  Kolja Eppert;Stephen W Scherer;Hilmi Ozcelik;Rosa Pirone

  1120
  Citations

• A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

  Brian F. O'Dowd;Michael Heiber;Audrey Chan;Henry H.Q. Heng

  1071
  Citations

• The relation between genotype and phenotype in cystic fibrosis--analysis of the most common mutation (delta F508).

  Eitan Kerem;Mary Corey;Bat-sheva Kerem;Johanna Rommens

  927
  Citations

• Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer.

  Mitchell L. Drumm;Heidi A. Pope;William H. Cliff;Johanna M. Rommens

  821
  Citations

• Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly

  E. Belloni;M. Muenke;E. Roessler;G. Traverso

  803
  Citations

• Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

  R. Mo;A. M. Freer;D. L. Zinyk;M. A. Crackower

  704
  Citations

• Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor

  Carol L. Freund;Cheryl Y. Gregory-Evans;Takahisa Furukawa;Myrto Papaioannou

  692
  Citations

• High-resolution mapping of mammalian genes by in situ hybridization to free chromatin.

  H. H. Q. Heng;J. Squire;Lap-Chee Tsui

  691
  Citations

• A mutation in CFTR produces different phenotypes depending on chromosomal background

  S. Kiesewetter;M. Macek;C. Davis;S. M. Curristin

  614
  Citations

• Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

  Norbert Kartner;John W. Hanrahan;Tim J. Jensen;A. Leonard Naismith

  604
  Citations

• Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy.

  Berge A. Minassian;R. Lee Jeffrey;Jo Anne Herbrick;Jack Huizenga

  594
  Citations

• A cluster of cystic fibrosis mutations in the first nucleotide-binding fold of the cystic fibrosis conductance regulator protein.

  Garry R. Cutting;Laura M. Kasch;Beryl J. Rosenstein;Julian Zielenski

  576
  Citations

• Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

  Richard Rozmahel;Michael Wilschanski;Angabin Matin;Suzanne Plyte

  548
  Citations

• Modes of DAPI banding and simultaneous in situ hybridization

  Henry H. Q. Heng;Lap-Chee Tsui

  503
  Citations

• A suggested nomenclature for designating mutations

  Arthur L. Beaudet;Lap-Chee Tsui

  449
  Citations