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Genetics

D-Index
57
Citations
12248
World Ranking
3410
National Ranking
1473

Overview

Ann Harris is affiliated with Case Western Reserve University in the United States. The research conducted focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Their work spans several key subfields, including molecular biology, pulmonary and respiratory medicine, genetics, surgery, and electrical and electronic engineering.

The scientist's research covers a variety of topics, notably cystic fibrosis research advances, neonatal respiratory health research, epigenetics and DNA methylation, energy harvesting in wireless networks, CRISPR and genetic engineering, genomics and chromatin dynamics, and renal and related cancers.

Among the recent papers authored or coauthored by Ann Harris are:

  • An atlas of human proximal epididymis reveals cell-specific functions and distinct roles for CFTR, 2020, Life Science Alliance
  • Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction, 2020, Molecular Therapy
  • Cell function and identity revealed by comparative scRNA-seq analysis in human nasal, bronchial and epididymis epithelia, 2022, European Journal of Cell Biology
  • The FOXA1 transcriptional network coordinates key functions of primary human airway epithelial cells, 2020, American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells, 2020, Nucleic Acids Research

Ann Harris frequently collaborates with a number of coauthors, including:

  • Shih-Hsing Leir
  • Alekh Paranjapye
  • Jenny L. Kerschner
  • Shiyi Yin
  • Monali NandyMazumdar

The venues where Ann Harris most often publishes include:

  • UNC Libraries
  • Journal of Cellular and Molecular Medicine
  • Journal of Cystic Fibrosis
  • Physiological Genomics
  • Cell and Tissue Research

The body of work reflects a sustained focus on pulmonary and genetic aspects of disease, with specific attention given to cystic fibrosis and airway epithelial cell biology. The combination of molecular techniques and clinical perspectives indicates interdisciplinary engagement across biochemistry and medicine.

Best Publications

  • Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

    Alison J. Coffey;Robert A. Brooksbank;Oliver Brandau;Toshitaka Oohashi

  • Immunocytochemical localization of the cystic fibrosis gene product CFTR.

    Isabelle Crawford;Peter C. Maloney;Pamela L. Zeitlin;William B. Guggino

  • The Phenotypic Consequences of CFTR Mutations

    Rebecca K. Rowntree;Ann Harris

  • Human enteric defensins: Gene structure and developmental expression

    Eric B. Mallow;Ann Harris;Nita Salzman;John P. Russell

  • Oligosaccharides Expressed on MUC1 Produced by Pancreatic and Colon Tumor Cell Lines

    Michael D. Burdick;Ann Harris;Colm J. Reid;Takeshi Iwamura

  • Mucin gene expression during differentiation of human airway epithelia in vitro. Muc4 and muc5b are strongly induced.

    Susan H. Bernacki;Andrew L. Nelson;Lubna Abdullah;John K. Sheehan

  • Two types of chloride channel on duct cells cultured from human fetal pancreas.

    M. A. Gray;A. Harris;L. Coleman;J. R. Greenwell

  • Developmental Expression of Mucin Genes in the Human Respiratory Tract

    Colm J. Reid;Stephen Gould;Ann Harris

  • A Structured Viroid RNA Serves as a Substrate for Dicer-Like Cleavage To Produce Biologically Active Small RNAs but Is Resistant to RNA-Induced Silencing Complex-Mediated Degradation

    Asuka Itaya;Xuehua Zhong;Ralf Bundschuh;Yijun Qi

  • Identification of MUC1 proteolytic cleavage sites in vivo.

    Simon Parry;Howard S. Silverman;Kimberly McDermott;Anthony Willis

  • Anion selectivity and block of the small-conductance chloride channel on pancreatic duct cells

    M. A. Gray;C. E. Pollard;A. Harris;L. Coleman

  • Expression of the cystic fibrosis gene in human foetal tissues

    Ann E.O. Trezise;Julie A. Chambers;Catherine J. Wardle;Stephen Gould

  • Molecular genetics of metachromatic leukodystrophy

    V Gieselmann;J Zlotogora;A Harris;D A Wenger

  • MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene.

    Austin E. Gillen;Nehal Gosalia;Shih Hsing Leir;Ann Harris

  • Desensitization of oxytocin receptors in human myometrium

    Sylvain Phaneuf;Gergely Asbóth;María P. Carrasco;Belén Rodríguez Liñares

  • Overexpression of MUC1 reconfigures the binding properties of tumor cells

    Kimberly M. McDermott;Paul R. Crocker;Ann Harris;Michael D. Burdick

  • The desensitization of oxytocin receptors in human myometrial cells is accompanied by down-regulation of oxytocin receptor messenger RNA

    S Phaneuf;G Asbóth;M P Carrasco;G N Europe-Finner

  • Random association of Epstein-Barr virus genomes with host cell metaphase chromosomes in Burkitt's lymphoma-derived cell lines.

    A Harris;B D Young;B E Griffin

  • Developmental expression of mucin genes MUC1 and MUC2

    Julie A. Chambers;Michael A. Hollingsworth;Ann E.O. Trezise;Ann Harris

  • Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

    Christopher J. Ott;Neil P. Blackledge;Neil P. Blackledge;Jenny L. Kerschner;Shih Hsing Leir

Frequent Co-Authors

Michael A. Hollingsworth
Michael A. Hollingsworth University of Nebraska Medical Center
Scott E. Eggener
Scott E. Eggener University of Chicago
Margarida D. Amaral
Margarida D. Amaral University of Lisbon
Gregory E. Crawford
Gregory E. Crawford Duke University
Frances Flinter
Frances Flinter Guy's and St Thomas' NHS Foundation Trust
Howard R. Morris
Howard R. Morris Imperial College London
Anne Dell
Anne Dell Imperial College London
Wanda K. O'Neal
Wanda K. O'Neal University of North Carolina at Chapel Hill
Lingyun Song
Lingyun Song Duke University
Scott H. Randell
Scott H. Randell University of North Carolina at Chapel Hill

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