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Mitsuhiko Ikura
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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
104
Citations
48176
World Ranking
1237
National Ranking
31

Mitsuhiko Ikura publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Mitsuhiko Ikura sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 419 publications — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Mitsuhiko Ikura D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Mitsuhiko Ikura sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 104 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Mitsuhiko Ikura is affiliated with the Princess Margaret Cancer Centre in Canada. Their research predominantly focuses on biochemistry, genetics, and molecular biology, with considerable contributions in the subfields of molecular biology, cell biology, materials chemistry, cancer research, and surgery.

The scientist's work covers key topics including:

  • Protein Kinase Regulation and GTPase Signaling
  • Cellular transport and secretion
  • Protein Tyrosine Phosphatases
  • Enzyme Structure and Function
  • Mitochondrial Function and Pathology
  • Cellular Mechanics and Interactions
  • Cancer, Hypoxia, and Metabolism

Mitsuhiko Ikura has published extensively, with a total of 89 works contributing to these fields. Their frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angewandte Chemie
  • Angewandte Chemie International Edition
  • Proceedings of the National Academy of Sciences
  • Journal of Cell Science

Significant recent papers authored or co-authored by Mitsuhiko Ikura are:

  • Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement, 2020, Angewandte Chemie International Edition
  • Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane, 2020, Proceedings of the National Academy of Sciences
  • The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors, 2021, Nature Communications
  • Real-Time In-Cell NMR Reveals the Intracellular Modulation of GTP-Bound Levels of RAS, 2020, Cell Reports
  • Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization, 2021, Chemical Science

Frequent collaborators in their research include:

  • Christopher B. Marshall
  • Geneviève M. C. Gasmi-Seabrook
  • Teklab Gebregiworgis
  • Masahiro Enomoto
  • Michael Ohh

Best Publications

  • Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

    Atsushi Miyawaki;Juan Llopis;Roger Heim;J. Michael McCaffery

  • Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins

    Dominique Marion;Mitsuhiko Ikura;Rolf Tschudin;Ad Bax

  • Solution structure of a calmodulin-target peptide complex by multidimensional NMR.

    M. Ikura;G.M. Clore;A.M. Gronenborn;Guang Zhu;Guang Zhu

  • Three-dimensional triple-resonance NMR Spectroscopy of isotopically enriched proteins

    Lewis E Kay;Mitsuhiko Ikura;Rolf Tschudin;Ad Bax

  • A novel approach for sequential assignment of proton, carbon-13, and nitrogen-15 spectra of larger proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin

    Mitsuhiko Ikura;Lewis E. Kay;Ad Bax

  • Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible.

    Gaetano Barbato;Mitsuhiko Ikura;Lewis E. Kay;Richard W. Pastor

  • Molecular and structural basis of target recognition by calmodulin.

    Anna Crivici;Mitsuhiko Ikura

  • Calcium-induced conformational transition revealed by the solution structure of apo calmodulin.

    Mingjie Zhang;Toshiyuki Tanaka;Mitsuhiko Ikura

  • Structural basis of calcium-induced E-cadherin rigidification and dimerization

    Bhushan Nagar;Michael Overduin;Michael Overduin;Mitsuhiko Ikura;Mitsuhiko Ikura;James M. Rini

  • Calmodulin in Action: Diversity in Target Recognition and Activation Mechanisms

    Klaus P. Hoeflich;Mitsuhiko Ikura

  • Calcium binding and conformational response in EF-hand proteins

    Mitsuhiko Ikura

  • Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins

    Ad Bax;Mitsuhiko Ikura;Lewis E Kay;Dennis A Torchia

  • MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli.

    Yonglong Zhang;Junjie Zhang;Klaus P Hoeflich;Mitsuhiko Ikura

  • Calmodulin Target Database

    Kyoko L. Yap;Justin Kim;Kevin Truong;Marc Sherman

  • Cadherins in embryonic and neural morphogenesis

    Ulrich Tepass;Kevin Truong;Dorothea Godt;Mitsuhiko Ikura

  • A Novel Approach for Sequential Assignment of 1H, 13C, and 15N Spectra of Larger Proteins: Heteronuclear Triple-Resonance Three-Dimensional NMR Spectroscopy. Application to Calmodulin

    Mitsuhiko Ikura;Lewis E. Kay;Ad Bax

  • Improved solvent suppression in one-and two-dimensional NMR spectra by convolution of time-domain data

    Dominique Marion;Mitsuhiko Ikura;Ad Bax

  • Molecular mechanics of calcium–myristoyl switches

    James B. Ames;Rieko Ishima;Toshiyuki Tanaka;Jeffrey I. Gordon

  • Solution structure of the epithelial cadherin domain responsible for selective cell adhesion.

    Michael Overduin;Timothy S. Harvey;Stefan Bagby;Kit I. Tong

  • The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo.

    Kevin Truong;Mitsuhiko Ikura

Frequent Co-Authors

Ad Bax
Ad Bax National Institutes of Health
Lewis E. Kay
Lewis E. Kay University of Toronto
Toshiyuki Tanaka
Toshiyuki Tanaka Hyogo University of Health Sciences
Masayori Inouye
Masayori Inouye Rutgers, The State University of New Jersey
Vuk Stambolic
Vuk Stambolic University of Toronto
Lubert Stryer
Lubert Stryer Stanford University
Kazuo Yamamoto
Kazuo Yamamoto University of Tokyo
Robert Rottapel
Robert Rottapel University of Toronto
Ming-Sound Tsao
Ming-Sound Tsao Princess Margaret Cancer Centre
Atsushi Miyawaki
Atsushi Miyawaki RIKEN

External Links

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Best Scientists Citing Mitsuhiko Ikura

Masayori Inouye

Masayori Inouye

Rutgers, The State University of New Jersey

Publications: 107

Lewis E. Kay

Lewis E. Kay

University of Toronto

Publications: 105

Peter E. Wright

Peter E. Wright

Scripps Research Institute

Publications: 85

Ad Bax

Ad Bax

National Institutes of Health

Publications: 81

Gerhard Wagner

Gerhard Wagner

Harvard University

Publications: 81

Atsushi Miyawaki

Atsushi Miyawaki

RIKEN

Publications: 75

Kurt Wüthrich

Kurt Wüthrich

ETH Zurich

Publications: 70

Angela M. Gronenborn

Angela M. Gronenborn

University of Pittsburgh

Publications: 64

Walter J. Chazin

Walter J. Chazin

Vanderbilt University

Publications: 61

Colin W. Taylor

Colin W. Taylor

University of Cambridge

Publications: 60

Gaetano T. Montelione

Gaetano T. Montelione

Rensselaer Polytechnic Institute

Publications: 54

G. Marius Clore

G. Marius Clore

National Institutes of Health

Publications: 52

Katsuhiko Mikoshiba

Katsuhiko Mikoshiba

ShanghaiTech University

Publications: 51

Robert E. Campbell

Robert E. Campbell

University of Tokyo

Publications: 50

Karl-Wilhelm Koch

Karl-Wilhelm Koch

Carl von Ossietzky University of Oldenburg

Publications: 48

Rolf Boelens

Rolf Boelens

Utrecht University

Publications: 45

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