World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
16639
World Ranking
5717
National Ranking
46

Overview

Kwang-Hyun Cho is affiliated with the Korea Advanced Institute of Science and Technology in South Korea. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, which accounts for a significant portion of their work. Other subfields they contribute to include Oncology, Computational Theory and Mathematics, Modeling and Simulation, and Biomedical Engineering.

The scientist has produced research on a diverse range of topics, including Gene Regulatory Network Analysis, Bioinformatics and Genomic Networks, Single-cell and Spatial Transcriptomics, Microbial Metabolic Engineering and Bioproduction, Cancer Cells and Metastasis, Computational Drug Discovery Methods, and Epigenetics and DNA Methylation.

Kwang-Hyun Cho has contributed to several peer-reviewed articles published in a variety of journals. Some of their recent notable papers include:

  • A logical network-based drug-screening platform for Alzheimer's disease representing pathological features of human brain organoids, 2021, Nature Communications
  • PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression, 2022, Nature Communications
  • Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts, 2020, Proceedings of the National Academy of Sciences
  • Realizing Cancer Precision Medicine by Integrating Systems Biology and Nanomaterial Engineering, 2020, Advanced Materials
  • Critical transition and reversion of tumorigenesis, 2023, Experimental & Molecular Medicine

Their frequent co-authors include Jeong-Ryeol Gong, Chun-Kyung Lee, Sang-Min Park, Chae Young Hwang, and Young-Hyun Han. These collaborations have resulted in multiple joint publications within their fields of study.

Kwang-Hyun Cho's research outputs are often published in journals such as Advanced Science, Nature Communications, Scientific Reports, Proceedings of the National Academy of Sciences, and Advanced Materials, indicating their engagement with both specialized and broad scientific audiences.

Best Publications

  • Modulation of Skin Collagen Metabolism in Aged and Photoaged Human Skin In Vivo

    Jin Ho Chung;Jin Young Seo;Hai Ryung Choi;Mi Kyung Lee

  • Aging- and photoaging-dependent changes of enzymic and nonenzymic antioxidants in the epidermis and dermis of human skin in vivo.

    Gi-eun Rhie;Mi Hee Shin;Jin Young Seo;Won Woo Choi

  • Cutaneous Photodamage in Koreans: Influence of Sex, Sun Exposure, Smoking, and Skin Color

    Jin Ho Chung;Seong Hun Lee;Choon Shik Youn;Byung Joo Park

  • Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle.

    Ji Hyun Han;Oh Sang Kwon;Jin Ho Chung;Kwang Hyun Cho

  • Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κ B Signal Transduction Pathway:

    Kwang Hyun Cho;Sung Young Shin;Walter Kolch;Olaf Wolkenhauer

  • Fuzzy Clustering of Short Time-Series and Unevenly Distributed Sampling Points

    Carla S. Möller-Levet;Frank Klawonn;Kwang-Hyun Cho;Olaf Wolkenhauer

  • Dual mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes

    Jin Ho Chung;Ji Hyun Han;Eun Ju Hwang;Jin Young Seo

  • Paracrine effects of adipose-derived stem cells on keratinocytes and dermal fibroblasts.

    Seung Ho Lee;Sang Yun Jin;Jin Seok Song;Kyle K. Seo

  • Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway.

    Sung Young Shin;Oliver Rath;Sang Mok Choo;Frances Fee

  • Cooperative activation of PI3K by Ras and Rho family small GTPases.

    Hee Won Yang;Min-Gyoung Shin;Sangkyu Lee;Jeong-Rae Kim;Jeong-Rae Kim

  • A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK Pathways

    Kim D;Rath O;Kolch W;Cho Kh

  • Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage

    Minsoo Choi;Jue Shi;Sung Hoon Jung;Sung Hoon Jung;Xi Chen

  • Human hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG).

    O.S. Kwon;J.H. Han;H.G. Yoo;J.H. Chung

  • Modeling and simulation of intracellular dynamics: choosing an appropriate framework

    O. Wolkenhauer;M. Ullah;W. Kolch;Kwang-Hyun Cho

  • Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition.

    Sung Young Shin;Oliver Rath;Armin Zebisch;Armin Zebisch;Sang Mok Choo

  • Coupled feedback loops form dynamic motifs of cellular networks.

    Jeong-Rae Kim;Yeoin Yoon;Kwang-Hyun Cho

  • Augmentation of UV-induced skin wrinkling by infrared irradiation in hairless mice.

    Hyeon Ho Kim;Min Jung Lee;Se Rah Lee;Kyu Han Kim

  • In silico identification of the key components and steps in IFN-γ induced JAK-STAT signaling pathway

    Zhike Zi;Kwang-Hyun Cho;Myong-Hee Sung;Xuefeng Xia

  • Infrared plus visible light and heat from natural sunlight participate in the expression of MMPs and type I procollagen as well as infiltration of inflammatory cell in human skin in vivo.

    Soyun Cho;Min Jung Lee;Min Jung Lee;Mi Sun Kim;Mi Sun Kim;Serah Lee;Serah Lee

  • Differential effects of photoaging vs intrinsic aging on the vascularization of human skin.

    Jin Ho Chung;Kiichiro Yano;Mi Kyung Lee;Choon Shik Youn

Frequent Co-Authors

Olaf Wolkenhauer
Olaf Wolkenhauer University of Rostock
Jin Ho Chung
Jin Ho Chung Seoul National University
Seibum B. Choi
Seibum B. Choi Korea Advanced Institute of Science and Technology
Walter Kolch
Walter Kolch University College Dublin
Won Do Heo
Won Do Heo Korea Advanced Institute of Science and Technology
Jun Soo Kwon
Jun Soo Kwon Seoul National University
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Boris N. Kholodenko
Boris N. Kholodenko University College Dublin
Helen M. Byrne
Helen M. Byrne University of Oxford
Ian Postlethwaite
Ian Postlethwaite Newcastle University

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