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D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
19777
World Ranking
15357
National Ranking
139

Overview

Bon-Kyoung Koo is affiliated with the Austrian Academy of Sciences in Austria. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a significant focus on medicine. The main subfields encompassing their work include molecular biology, oncology, cancer research, genetics, and pulmonary and respiratory medicine.

The scientist's research interests cover a variety of topics, notably cancer cells and metastasis, pluripotent stem cells research, Wnt/β-catenin signaling in development and cancer, CRISPR and genetic engineering, cancer genomics and diagnostics, cancer-related gene regulation, and renal and related cancers.

Bon-Kyoung Koo has contributed to multiple publications, with several appearing in frequently targeted venues such as bioRxiv (Cold Spring Harbor Laboratory), Experimental & Molecular Medicine, Cell Stem Cell, Nature Communications, and Development.

Frequent co-authors collaborating with Bon-Kyoung Koo include:

  • Jihoon Kim
  • Ji-Hyun Lee
  • Heetak Lee
  • Gabriele Colozza
  • Joo-Hyeon Lee

Among the recent papers associated with Bon-Kyoung Koo are:

  • Human organoids: model systems for human biology and medicine, 2020, Nature Reviews Molecular Cell Biology
  • Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration, 2020, Cell Stem Cell
  • Tracing oncogene-driven remodelling of the intestinal stem cell niche, 2021, Nature
  • Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses, 2020, mBio
  • Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine, 2020, Cell Death and Differentiation

Best Publications

  • Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

    Gerald Schwank;Bon Kyoung Koo;Valentina Sasselli;Johanna F. Dekkers

  • Human organoids: model systems for human biology and medicine.

    Jihoon Kim;Bon-Kyoung Koo;Juergen A. Knoblich;Juergen A. Knoblich

  • Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

    Wim De Lau;Nick Barker;Nick Barker;Teck Y. Low;Bon Kyoung Koo

  • Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

    Laura Broutier;Gianmarco Mastrogiovanni;Monique M.A. Verstegen;Hayley E. Francies

  • Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

    Bon-Kyoung Koo;Maureen Spit;Ingrid Jordens;Teck Y. Low

  • The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

    Javier Muñoz;Daniel E Stange;Arnout G Schepers;Marc van de Wetering

  • Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium

    Margherita Y Turco;Lucy Gardner;Jasmine Hughes;Tereza Cindrova-Davies

  • Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

    Laura Broutier;Amanda Andersson-Rolf;Christopher J. Hindley;Sylvia F. Boj

  • Differentiated Troy+ Chief Cells Act as Reserve Stem Cells to Generate All Lineages of the Stomach Epithelium

    Daniel E. Stange;Daniel E. Stange;Bon-Kyoung Koo;Bon-Kyoung Koo;Meritxell Huch;Greg Sibbel

  • Modeling mouse and human development using organoid cultures.

    Meritxell Huch;Bon-Kyoung Koo

  • Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration.

    Jinwook Choi;Jong-Eun Park;Georgia Tsagkogeorga;Motoko Yanagita

  • Controlled gene expression in primary Lgr5 organoid cultures

    Bon Kyoung Koo;Daniel E. Stange;Toshiro Sato;Toshiro Sato;Wouter Karthaus

  • DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome

    Kate Joanne Howell;Kate Joanne Howell;Judith Kraiczy;Komal M. Nayak;Marco Gasparetto

  • Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis

    Kosaku Nanki;Kohta Toshimitsu;Ai Takano;Masayuki Fujii

  • Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.

    Bon Kyoung Koo;Hyoung Soo Lim;Ran Song;Mi Jeong Yoon

  • A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal

    Johan H. van Es;Andrea Haegebarth;Pekka Kujala;Pekka Kujala;Shalev Itzkovitz

  • Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts

    Jurian Schuijers;Jan Philipp Junker;Michal Mokry;Pantelis Hatzis

  • Human gastric cancer modelling using organoids

    Therese Seidlitz;Sebastian R Merker;Alexander Rothe;Falk Zakrzewski

  • ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

    Jarom y Heijmans;Jooske F. van Lidth de Jeude;Bon-Kyoung Koo;Sanne L Rosekrans

  • A crucial role of WW45 in developing epithelial tissues in the mouse

    Joo Hyeon Lee;Tae Shin Kim;Tae Hong Yang;Bon Kyoung Koo

Frequent Co-Authors

Young-Yun Kong
Young-Yun Kong Seoul National University
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Benjamin D. Simons
Benjamin D. Simons University of Cambridge
Johan H. van Es
Johan H. van Es Utrecht University
Cheol-Hee Kim
Cheol-Hee Kim Chungnam National University
Marc van de Wetering
Marc van de Wetering Royal Netherlands Academy of Arts and Sciences
Alexander van Oudenaarden
Alexander van Oudenaarden University Medical Center Utrecht
William C. Skarnes
William C. Skarnes Wellcome Sanger Institute
Lucy Gardner
Lucy Gardner University of Cambridge
Nick Barker
Nick Barker Agency for Science, Technology and Research

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