World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
109
Citations
51737
World Ranking
547
National Ranking
22

Medicine

D-Index
111
Citations
53207
World Ranking
5282
National Ranking
200

Overview

Edwin Cuppen is affiliated with Utrecht University in the Netherlands and is active in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their research spans subfields including Cancer Research, Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, and Genetics.

Their work covers a range of topics with a focus on Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, Epigenetics and DNA Methylation, Lung Cancer Treatments and Mutations, Genomics and Rare Diseases, Colorectal Cancer Treatments and Studies, and Cancer Immunotherapy and Biomarkers.

Frequent publication venues for Edwin Cuppen's research include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Annals of Oncology, Cancer Research, and Scientific Reports.

Notable recent papers authored or co-authored by Edwin Cuppen include:

  • SARS-CoV-2 productively infects human gut enterocytes, 2020, Science
  • Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli, 2020, Nature
  • Pan-cancer landscape of homologous recombination deficiency, 2020, Nature Communications
  • SARS-CoV-2 Productively Infects Human Gut Enterocytes, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Patient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug Responses, 2020, Cell Reports

The scientist collaborates regularly with a group of co-authors including Arne van Hoeck, Paul Roepman, Martijn P. Lolkema, Emile E. Voest, and Peter Priestley, reflecting a network of frequent research partnerships.

Best Publications

  • Organoid Models of Human and Mouse Ductal Pancreatic Cancer

    Sylvia F. Boj;Chang Il Hwang;Chang Il Hwang;Lindsey A. Baker;Lindsey A. Baker;Iok In Christine Chio;Iok In Christine Chio

  • Sambamba: fast processing of NGS alignment formats

    Artem Tarasov;Albert J. Vilella;Edwin Cuppen;Isaac J. Nijman

  • SARS-CoV-2 productively infects human gut enterocytes.

    Mart M. Lamers;Joep Beumer;Jelte van der Vaart;Kèvin Knoops

  • Phylogenetic Shadowing and Computational Identification of Human microRNA Genes

    Eugene Berezikov;Victor Guryev;José van de Belt;Erno Wienholds

  • Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

    Meritxell Huch;Helmuth Gehart;Ruben van Boxtel;Karien Hamer

  • Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

    Gerald Schwank;Bon Kyoung Koo;Valentina Sasselli;Johanna F. Dekkers

  • A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

    Norman Sachs;Joep de Ligt;Oded Kopper;Ewa Gogola

  • Mammalian mirtron genes.

    Eugene Berezikov;Wei Jen Chung;Jason Willis;Edwin Cuppen

  • Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli.

    Cayetano Pleguezuelos-Manzano;Jens Puschhof;Axel Rosendahl Huber;Arne van Hoeck

  • Sequential cancer mutations in cultured human intestinal stem cells

    Jarno Drost;Richard H. van Jaarsveld;Bas Ponsioen;Cheryl Zimberlin

  • Long-term expanding human airway organoids for disease modeling

    Norman Sachs;Angelos Papaspyropoulos;Domenique D. Zomer-van Ommen;Inha Heo

  • Tissue-specific mutation accumulation in human adult stem cells during life

    Francis Blokzijl;Joep de Ligt;Myrthe Jager;Valentina Sasselli

  • Pan-cancer whole-genome analyses of metastatic solid tumours

    Peter Priestley;Jonathan Baber;Martijn P. Lolkema;Neeltje Steeghs

  • Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

    Wouter R. Karthaus;Phillip J. Iaquinta;Jarno Drost;Ana Gracanin

  • A systematic genome-wide analysis of zebrafish protein-coding gene function

    Ross N. W. Kettleborough;Elisabeth M. Busch-Nentwich;Steven A. Harvey;Christopher M. Dooley

  • Diversity of microRNAs in human and chimpanzee brain.

    Eugene Berezikov;Fritz Thuemmler;Linda W van Laake;Ivanela Kondova

  • Approaches to microRNA discovery

    Eugene Berezikov;Edwin Cuppen;Ronald H A Plasterk

  • The microRNA-producing enzyme Dicer1 is essential for zebrafish development

    Erno Wienholds;Marco J Koudijs;Freek J M van Eeden;Edwin Cuppen

  • MutationalPatterns: comprehensive genome-wide analysis of mutational processes

    Francis Blokzijl;Roel Janssen;Ruben van Boxtel;Edwin Cuppen

  • Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.

    Salo N. Ooft;Fleur Weeber;Krijn K. Dijkstra;Chelsea M. McLean

Frequent Co-Authors

Victor Guryev
Victor Guryev University Medical Center Groningen
Isaac J. Nijman
Isaac J. Nijman Utrecht University
Emile E. Voest
Emile E. Voest Antoni van Leeuwenhoek Hospital
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Wigard P. Kloosterman
Wigard P. Kloosterman Utrecht University
Eugene Berezikov
Eugene Berezikov University Medical Center Groningen
Michal Mokry
Michal Mokry Utrecht University
Ronald H. A. Plasterk
Ronald H. A. Plasterk University of Amsterdam
Judith R. Homberg
Judith R. Homberg Radboud University
Stefan Sleijfer
Stefan Sleijfer Erasmus University Rotterdam

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