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Medicine

D-Index
117
Citations
95409
World Ranking
4105
National Ranking
2248

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David A. Tuveson is affiliated with Cold Spring Harbor Laboratory in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on oncology and molecular biology subfields. The subfields of study emphasize Oncology, Molecular Biology, Cancer Research, Immunology, and Radiology, Nuclear Medicine, and Imaging.

The main topics of research addressed by Tuveson include Cancer Genomics and Diagnostics, Pancreatic and Hepatic Oncology Research, Cancer Cells and Metastasis, Epigenetics and DNA Methylation, Immune Cells in Cancer, Advances in Oncology and Radiotherapy, as well as Health and Medical Research Impacts.

Frequent publication venues for their work are:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • Cancer Discovery
  • Gastroenterology

Notable recent papers authored or co-authored by Tuveson include:

  • "A framework for advancing our understanding of cancer-associated fibroblasts," 2020, published in Nature Reviews. Cancer
  • "Diversity and Biology of Cancer-Associated Fibroblasts," 2020, published in Physiological Reviews
  • "Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution," 2020, published in Nature Genetics
  • "ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity," 2020, published in Nature
  • "Activated fibroblasts in cancer: Perspectives and challenges," 2023, published in Cancer Cell

Frequent co-authors collaborating with Tuveson include Youngkyu Park, Astrid Deschênes, Dennis Plenker, Faiyaz Notta, and Amber N. Habowski.

Among the awards received, Tuveson is recognized as a Member of the Association of American Physicians. No specific year was noted for this recognition.

Best Publications

  • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.

    George Daniel Demetri;Margaret von Mehren;Charles D. Blanke;Annick Diane Van Den Abbeele

  • A framework for advancing our understanding of cancer-associated fibroblasts

    Erik Sahai;Igor Astsaturov;Edna Cukierman;David G. DeNardo

  • Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

    Kenneth P. Olive;Michael A. Jacobetz;Christian J. Davidson;Aarthi Gopinathan;Aarthi Gopinathan

  • Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

    Sunil R. Hingorani;Emanuel F. Petricoin;Anirban Maitra;Vinodh Rajapakse

  • Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

    Sunil R. Hingorani;Lifu Wang;Asha S. Multani;Chelsea Combs

  • Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

    Heikki Joensuu;Peter J. Roberts;Maarit Sarlomo-Rikala;Leif C. Andersson

  • Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

    Gina M. DeNicola;Florian A. Karreth;Timothy J. Humpton;Aarthi Gopinathan

  • Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

    Daniel Öhlund;Daniel Öhlund;Daniel Öhlund;Abram Handly-Santana;Abram Handly-Santana;Giulia Biffi;Giulia Biffi;Ela Elyada;Ela Elyada

  • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

    Andrew V. Biankin;Andrew V. Biankin;Andrew V. Biankin;Nicola Waddell;Karin S. Kassahn;Marie Claude Gingras

  • Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

    Erica L. Jackson;Nicholas Willis;Kim Mercer;Roderick T. Bronson

  • Restoration of p53 function leads to tumour regression in vivo

    Andrea Ventura;David G. Kirsch;David G. Kirsch;Margaret E. McLaughlin;David A. Tuveson

  • Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.

    Christine Feig;James O. Jones;Matthew Kraman;Richard J. B. Wells

  • Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

    Ela Elyada;Ela Elyada;Mohan Bolisetty;Pasquale Laise;William F. Flynn

  • Organoid Models of Human and Mouse Ductal Pancreatic Cancer

    Sylvia F. Boj;Chang Il Hwang;Chang Il Hwang;Lindsey A. Baker;Lindsey A. Baker;Iok In Christine Chio;Iok In Christine Chio

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • Transcriptional Regulation by Nrf2

    Claudia Tonelli;Iok In Christine Chio;David A. Tuveson;David A. Tuveson

  • Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome.

    Kenneth P. Olive;David A. Tuveson;Zachary C. Ruhe;Bob Yin

  • Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

    Leisa Johnson;Kim Mercer;Kim Mercer;Doron Greenbaum;Doron Greenbaum;Roderick T. Bronson

  • The Pancreas Cancer Microenvironment

    Christine Feig;Aarthi Gopinathan;Albrecht Neesse;Derek S. Chan

  • KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

    Brian P. Rubin;Samuel Singer;Connie Tsao;Anette Duensing

Frequent Co-Authors

Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
George D. Demetri
George D. Demetri Dana-Farber Cancer Institute
Andrew V. Biankin
Andrew V. Biankin University of Glasgow
David J. Adams
David J. Adams Wellcome Sanger Institute
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Heikki Joensuu
Heikki Joensuu University of Helsinki
Jonathan A. Fletcher
Jonathan A. Fletcher Brigham and Women's Hospital
Christopher R. Vakoc
Christopher R. Vakoc Cold Spring Harbor Laboratory
Darryl J. Pappin
Darryl J. Pappin Cold Spring Harbor Laboratory

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