World's Best Scientists 2026 revealed!
Frans M.J. Debruyne

Frans M.J. Debruyne

D-Index & Metrics

Medicine

D-Index
93
Citations
32664
World Ranking
10867
National Ranking
129

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Surgery
  • Cancer

Prostate, Surgery, Urology, Pathology and Prostate cancer are his primary areas of study. His research in Prostate focuses on subjects like Hyperplasia, which are connected to Adenoma. His work deals with themes such as Internal medicine, Carcinoma and Transurethral microwave thermotherapy, which intersect with Surgery.

His Urology research integrates issues from Lower urinary tract symptoms, Randomized controlled trial, Antiandrogen and Urinary system. His study in Pathology is interdisciplinary in nature, drawing from both Cancer, Cancer research, Cadherin and Cellular differentiation. His Prostate cancer research includes themes of High-mobility group, Magnetic resonance imaging and In situ hybridization.

His most cited work include:

  • DD3::A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer (884 citations)
  • Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer. (568 citations)
  • Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. (565 citations)

What are the main themes of his work throughout his whole career to date?

Frans M.J. Debruyne mainly focuses on Surgery, Urology, Prostate, Internal medicine and Pathology. His work on Surgery is being expanded to include thematically relevant topics such as Bladder outlet obstruction. In the field of Urology, his study on Urinary bladder overlaps with subjects such as In patient.

Frans M.J. Debruyne combines subjects such as Radiology, Prostate cancer and Hyperplasia with his study of Prostate. The various areas that Frans M.J. Debruyne examines in his Internal medicine study include Gastroenterology, Endocrinology and Oncology. His Pathology research is multidisciplinary, incorporating elements of Cancer, Cancer research and Antibody.

He most often published in these fields:

  • Surgery (32.23%)
  • Urology (25.64%)
  • Prostate (20.77%)

What were the highlights of his more recent work (between 2001-2021)?

  • Surgery (32.23%)
  • Urology (25.64%)
  • Internal medicine (18.48%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Surgery, Urology, Internal medicine, Prostate cancer and Prostate. He works on Surgery which deals in particular with Randomized controlled trial. His work carried out in the field of Urology brings together such families of science as Lower urinary tract symptoms, Quality of life, Urinary system, Randomization and Prostate-specific antigen.

His research in Internal medicine intersects with topics in Endocrinology and Oncology. His Prostate cancer study integrates concerns from other disciplines, such as Clinical trial and Zoledronic acid. Frans M.J. Debruyne is interested in International Prostate Symptom Score, which is a branch of Prostate.

Between 2001 and 2021, his most popular works were:

  • Head-to-head Comparison of Transrectal Ultrasound-guided Prostate Biopsy Versus Multiparametric Prostate Resonance Imaging with Subsequent Magnetic Resonance-guided Biopsy in Biopsy-naïve Men with Elevated Prostate-specific Antigen: A Large Prospective Multicenter Clinical Study. (207 citations)
  • Efficacy and Safety of Long-Term Treatment with the Dual 5α-Reductase Inhibitor Dutasteride in Men with Symptomatic Benign Prostatic Hyperplasia (199 citations)
  • Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3, randomised controlled trial (154 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Surgery
  • Cancer

His primary areas of investigation include Surgery, Urology, Internal medicine, Quality of life and Tibial nerve. His Surgery study incorporates themes from Prostatectomy and General surgery. His Urology research incorporates elements of Lower urinary tract symptoms, Prostate, Urinary system, Randomization and Watchful waiting.

His Prostate research is multidisciplinary, relying on both Biopsy, Magnetic resonance imaging, Prostate cancer and Hazard ratio. His work on Nephrology, Erectile dysfunction, Randomized controlled trial and Gonadotropin-releasing hormone antagonist as part of general Internal medicine study is frequently linked to Vardenafil, therefore connecting diverse disciplines of science. He has included themes like Urination and Anesthesia in his Tibial nerve study.

Best Publications

  • DD3::A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer

    M.J.G. Bussemakers;A. van Bokhoven;G.W.C.T. Verhaegh;F.P. Smit

  • Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer.

    Donald L. Lamm;Ad P.M. Van Der Meijden;Alvaro Morales;Stanley A. Brosman

  • Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

    Umbas R;Schalken Ja;Aalders Tw;Carter Bs

  • Head-to-head Comparison of Transrectal Ultrasound-guided Prostate Biopsy Versus Multiparametric Prostate Resonance Imaging with Subsequent Magnetic Resonance-guided Biopsy in Biopsy-naïve Men with Elevated Prostate-specific Antigen: A Large Prospective Multicenter Clinical Study.

    Marloes van der Leest;Erik Cornel;Bas Israël;Rianne Hendriks

  • Decreased E-Cadherin Expression Is Associated with Poor Prognosis in Patients with Prostate Cancer

    R. Umbas;W. B. Isaacs;P. P. Bringuier;H. E. Schaafsma

  • Decreased E-Cadherin Immunoreactivity Correlates with Poor Survival in Patients with Bladder Tumors

    P. P. Bringuier;R. Umbas;H. E. Schaafsma;H. F. M. Karthaus

  • Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3, randomised controlled trial

    Abdel Rahmène Azzouzi;Sébastien Vincendeau;Eric Barret;Antony Cicco

  • 4–Year Follow–Up Results of a European Prospective Randomized Study on Neoadjuvant Hormonal Therapy prior to Radical Prostatectomy in T2–3N0M0 Prostate Cancer

    Claude C. Schulman;Frans M.J. Debruyne;Gerhard Forster;Francesco P. Selvaggi

  • Comparison of a phytotherapeutic agent (Permixon) with an alpha-blocker (Tamsulosin) in the treatment of benign prostatic hyperplasia: a 1-year randomized international study.

    Frans Debruyne;Gary Koch;Peter Boyle;Fernando Calais Da Silva

  • Efficacy and Safety of Long-Term Treatment with the Dual 5α-Reductase Inhibitor Dutasteride in Men with Symptomatic Benign Prostatic Hyperplasia

    Frans Debruyne;Jack Barkin;Peter van Erps;Mario Reis

  • Sustained-Release Alfuzosin, Finasteride and the Combination of Both in the Treatment of Benign Prostatic Hyperplasia

    F.M.J. Debruyne;A. Jardin;D. Colloi;L. Resel

  • Prognostic value of cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120cas) in bladder tumors.

    Toru Shimazui;Jack A. Schalken;Laurence A. Giroldi;Cornelius F. J. Jansen

  • Androgen-targeted therapy in men with prostate cancer: evolving practice and future considerations

    E. David Crawford;Axel Heidenreich;Axel Heidenreich;Nathan Lawrentschuk;Bertrand Tombal

  • Predictability of Recurrent and Progressive Disease in Individual Patients with Primary Superficial Bladder Cancer

    L.A.L.M. Kiemeney;J.A. Witjes;R.P. Heijbroek;A.L.M. Verbeek

  • Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer.

    A P Verhagen;F C Ramaekers;T W Aalders;H E Schaafsma

  • POSTERIOR TIBIAL NERVE STIMULATION AS NEUROMODULATIVE TREATMENT OF LOWER URINARY TRACT DYSFUNCTION

    Michael R. van Balken;Vera Vandoninck;Karel W.H. Gisolf;Henk Vergunst

  • Decreased Expression of E-Cadherin in the Progression of Rat Prostatic Cancer

    Marion J. G. Bussemakers;Reindert J. A. van Moorselaar;Laurence A. Giroldi;Tomohiko Ichikawa

  • Molecular Genetics and Epidemiology of Prostate Carcinoma

    Emiel Ruijter;Christina van de Kaa;Gary Miller;Dirk Ruiter

  • Metastasectomy in renal cell carcinoma: A multicenter retrospective analysis.

    H.G. van der Poel;J.A. Roukema;S. Horenblas;A.N. van Geel

  • Differential expression of keratins in the basal and luminal compartments of rat prostatic epithelium during degeneration and regeneration.

    Anja P. M. Verhagen;Tilly W. Aalders;Frans C. S. Ramaekers;Frans M. J. Debruyne

Frequent Co-Authors

Jack A. Schalken
Jack A. Schalken Radboud University
Lambertus A. Kiemeney
Lambertus A. Kiemeney Radboud University
Jean J.M.C.H. de la Rosette
Jean J.M.C.H. de la Rosette Istanbul Medipol University
Claude Schulman
Claude Schulman Université Libre de Bruxelles
Peter F.A. Mulders
Peter F.A. Mulders Radboud University
Richard Sylvester
Richard Sylvester European Organisation for Research and Treatment of Cancer
Alexandre R. Zlotta
Alexandre R. Zlotta University Health Network
Jelle O. Barentsz
Jelle O. Barentsz Radboud University
Arend Heerschap
Arend Heerschap Radboud University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students considering a career in medicine but seeking alternative or complementary paths, online nursing degrees are a flexible and affordable option. The growing need for skilled healthcare professionals means there are a variety of programs to fit different schedules and ambitions.

Those starting their journey may benefit from affordable nursing programs online, which provide foundational training for aspiring nurses. Registered nurses wanting to advance their skills and earning potential often pursue the rn to bsn cheapest programs to complete their bachelor’s degree at lower cost.

For those aiming for advanced practice roles, it's possible to enroll in affordable np programs that prepare students for the clinical and leadership demands of nurse practitioner careers. Alternatively, professionals interested in teaching, research, or leadership positions should consider a phd nursing education online to open doors in academia and healthcare administration.

Exploring these pathways allows students to contribute to healthcare in meaningful ways, often with the flexibility of online learning and the potential for reduced costs.

Best Scientists Citing Frans M.J. Debruyne

Trending Scientists