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Jack A. Schalken

Jack A. Schalken

D-Index & Metrics

Medicine

D-Index
96
Citations
34900
World Ranking
9635
National Ranking
372

Overview

Jack A. Schalken is affiliated with Radboud University in the Netherlands. Their research focuses primarily on medicine, with substantial contributions in biochemistry, genetics, and molecular biology. The scientist's subfields of study include pulmonary and respiratory medicine, cancer research, oncology, molecular biology, and surgery.

Schalken's recent publications cover a range of topics related to cancer and molecular diagnostics. Notable papers include:

  • Detection and localization of early- and late-stage cancers using platelet RNA (2022, Cancer Cell)
  • Liquid biopsy in bladder cancer: State of the art and future perspectives (2022, Critical Reviews in Oncology/Hematology)
  • Clinical use of the SelectMDx urinary-biomarker test with or without mpMRI in prostate cancer diagnosis: a prospective, multicenter study in biopsy-naïve men (2021, Prostate Cancer and Prostatic Diseases)
  • 68Ga-PSMA-HBED-CC PET/CT imaging for adenoid cystic carcinoma and salivary duct carcinoma: a phase 2 imaging study (2020, Theranostics)
  • Prostate Cancer Liquid Biopsy Biomarkers' Clinical Utility in Diagnosis and Prognosis (2021, Cancers)

Their research covers various main topics, including:

  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cancer-related molecular mechanisms research
  • Bladder and Urothelial Cancer Treatments
  • Cancer, Lipids, and Metabolism

Schalken often publishes in certain venues repeatedly. Frequent publication venues include:

  • The Prostate
  • Cancers
  • European Urology Open Science
  • Nature Reviews Urology
  • Oral Oncology

Collaboration is a significant part of their work, with frequent co-authors such as:

  • Niven Mehra
  • Gerald W. Verhaegh
  • Inge M. van Oort
  • Tapio Visakorpi
  • Onno van Hooij

Jack A. Schalken's scientific output reflects a deep engagement with clinical and molecular aspects of cancer, with a specific focus on prostate cancer, bladder cancer, and salivary gland tumors. Their work spans fundamental research in molecular biology to applied clinical diagnostics and imaging techniques.

Best Publications

  • DD3::A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer

    M.J.G. Bussemakers;A. van Bokhoven;G.W.C.T. Verhaegh;F.P. Smit

  • DD3PCA3-based Molecular Urine Analysis for the Diagnosis of Prostate Cancer

    Daphne Hessels;Jacqueline M.T. Klein Gunnewiek;Inge van Oort;Herbert F.M. Karthaus

  • DD3(PCA3), a very sensitive and specific marker to detect prostate tumors.

    Jacques B de Kok;Gerald W Verhaegh;Rian W Roelofs;Daphne Hessels

  • Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

    Umbas R;Schalken Ja;Aalders Tw;Carter Bs

  • Decreased E-Cadherin Expression Is Associated with Poor Prognosis in Patients with Prostate Cancer

    R. Umbas;W. B. Isaacs;P. P. Bringuier;H. E. Schaafsma

  • Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.

    Thorunn Rafnar;Patrick Sulem;Simon N Stacey;Frank Geller

  • Allelic loss of chromosomes 16q and 10q in human prostate cancer.

    B S Carter;C M Ewing;W S Ward;B F Treiger

  • Cadherin Switching in Human Prostate Cancer Progression

    K. Tomita;A. Van Bokhoven;G. J. L. H. Van Leenders;E. T. G. Ruijter

  • Prevention and early detection of prostate cancer

    Jack Cuzick;Mangesh A Thorat;Gerald L Andriole;Otis W Brawley;Otis W Brawley

  • Clinical utility of the PCA3 urine assay in European men scheduled for repeat biopsy.

    Alexander Haese;Alexandre de la Taille;Hendrik van Poppel;Michael Marberger

  • Bladder tumor markers beyond cytology: International Consensus Panel on bladder tumor markers

    Vinata B. Lokeshwar;Tomonori Habuchi;H. Barton Grossman;William M. Murphy

  • Decreased E-Cadherin Immunoreactivity Correlates with Poor Survival in Patients with Bladder Tumors

    P. P. Bringuier;R. Umbas;H. E. Schaafsma;H. F. M. Karthaus

  • ETS gene fusions in prostate cancer: from discovery to daily clinical practice.

    Scott A. Tomlins;Anders Bjartell;Arul M. Chinnaiyan;Guido Jenster

  • Detection of TMPRSS2-ERG Fusion Transcripts and Prostate Cancer Antigen 3 in Urinary Sediments May Improve Diagnosis of Prostate Cancer

    D. Hessels;F.P. Smit;G.W.C.T. Verhaegh;J.A. Witjes

  • Prospective Multicentre Evaluation of PCA3 and TMPRSS2-ERG Gene Fusions as Diagnostic and Prognostic Urinary Biomarkers for Prostate Cancer ☆

    Gisele H.J.M. Leyten;Daphne Hessels;Sander A. Jannink;Frank P. Smit

  • Androgen receptors in endocrine-therapy-resistant human prostate cancer

    T. H. Van Der Kwast;J. Schalken;J. A. Ruizeveld De Winter;C. C. J. Van Vroonhoven

  • Detection of High-grade Prostate Cancer Using a Urinary Molecular Biomarker–Based Risk Score

    Leander Van Neste;Rianne J Hendriks;Siebren Dijkstra;Geert Trooskens

  • Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss

    J T Dong;H Suzuki;S S Pin;G S Bova

  • Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

    S Gillessen;A Omlin;G Attard;J S de Bono

  • Cadherin Switching in Human Prostate Cancer Progression

    Jack A Schalken

Frequent Co-Authors

Peter F.A. Mulders
Peter F.A. Mulders Radboud University
Lambertus A. Kiemeney
Lambertus A. Kiemeney Radboud University
J. Alfred Witjes
J. Alfred Witjes Radboud University
Wim Van Criekinge
Wim Van Criekinge Ghent University
Alexandre de la Taille
Alexandre de la Taille Université Paris Cité
Michael Marberger
Michael Marberger Medical University of Vienna
Hartwig Huland
Hartwig Huland Universität Hamburg
Arnulf Stenzl
Arnulf Stenzl University of Tübingen
Winald R. Gerritsen
Winald R. Gerritsen Radboud University

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