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Immunology

D-Index
56
Citations
14809
World Ranking
3687
National Ranking
25

Overview

Ron N. Apte is affiliated with Ben-Gurion University of the Negev in Israel, focusing their research primarily on immunology and medicine. Their work extensively covers various aspects of immune cell function, immunotherapy, and cancer immunotherapy.

The main fields of study for Apte include Immunology and Microbiology with 13 publications, alongside Medicine with 9 publications. Subfields include Immunology, Molecular Biology, Oncology, Food Science, and Biological Psychiatry.

Apte's research investigates several key topics, including:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • IL-33, ST2, and ILC Pathways
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Tryptophan and brain disorders

The scientist has contributed to a number of academic papers published in a variety of scientific journals. Notable recent papers include:

  • Pathogenetic role and clinical significance of interleukin-1β in cancer, 2022, Immunology
  • Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity, 2021, Scientific Reports
  • Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α-STAT3 Axis, 2022, Cancer Immunology Research
  • Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction, 2020, Journal of Molecular and Cellular Cardiology
  • Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment, 2024, International Journal of Molecular Sciences

Regarding frequent publication venues, Apte's work has appeared in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunology
  • Scientific Reports
  • Cancer Immunology Research
  • International Journal of Molecular Sciences

Collaborations are a notable aspect of this scientist's career. Frequent co-authors include:

  • Elena Voronov (11 coauthored publications)
  • Marina Bersudsky (6 coauthored publications)
  • Omry Koren (4 coauthored publications)
  • Aner Ottolenghi (3 coauthored publications)
  • Mathumathi Krishnamohan (3 coauthored publications)

Ron N. Apte's research contributions provide insights into immunological mechanisms relevant to cancer biology, autoimmune conditions, and immune system regulation, with interdisciplinary applications spanning molecular biology, oncology, and microbiology.

Best Publications

  • IL-1 is required for tumor invasiveness and angiogenesis

    Elena Voronov;Dror S. Shouval;Yakov Krelin;Emanuela Cagnano

  • The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions.

    Ron N. Apte;Shahar Dotan;Moshe Elkabets;Malka R. White

  • IL-1α and IL-1β Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

    Peleg Rider;Yaron Carmi;Ofer Guttman;Alex Braiman

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription.

    Ariel Werman;Rachel Werman-Venkert;Rosalyn White;Jae-Kwon Lee

  • Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

    Idan Cohen;Peleg Rider;Yaron Carmi;Alex Braiman

  • Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation

    Irena Kaplanov;Yaron Carmi;Rachel Kornetsky;Avishai Shemesh

  • CD11b+/Gr-1+ Immature Myeloid Cells Mediate Suppression of T Cells in Mice Bearing Tumors of IL-1β-Secreting Cells

    Xiaoping Song;Yakov Krelin;Tatyana Dvorkin;Olle Bjorkdahl

  • Interleukin-1β–Driven Inflammation Promotes the Development and Invasiveness of Chemical Carcinogen–Induced Tumors

    Yakov Krelin;Elena Voronov;Shahar Dotan;Moshe Elkabets

  • IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.

    Moshe Elkabets;Vera S. G. Ribeiro;Vera S. G. Ribeiro;Charles A. Dinarello;Suzanne Ostrand-Rosenberg

  • Lack of Interleukin-1α or Interleukin-1β Inhibits Transformation of Steatosis to Steatohepatitis and Liver Fibrosis in Hypercholesterolemic Mice

    Yehuda Kamari;Aviv Shaish;Einav Vax;Einav Vax;Shay Shemesh;Shay Shemesh

  • Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy?

    Ron N. Apte;Elena Voronov

  • Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice

    Marina Bersudsky;Lotem Luski;Daniel Fishman;Rosalyn M White

  • Cytokine involvement in oocytes and early embryos.

    Mati Zolti;Zion Ben-Rafael;Ruth Meirom;Mordechai Shemesh

  • The Role of Macrophage-Derived IL-1 in Induction and Maintenance of Angiogenesis

    Yaron Carmi;Elena Voronov;Shahar Dotan;Nitza Lahat

  • Interleukin-1--a major pleiotropic cytokine in tumor-host interactions.

    Ron N Apte;Elena Voronov

  • Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour–host interactions

    Ron N. Apte;Yakov Krelin;Xiaoping Song;Shahar Dotan

  • The role IL-1 in tumor-mediated angiogenesis.

    Elena Voronov;Yaron Carmi;Yaron Carmi;Ron Nathan Apte

  • The Role of IL-1β in the Early Tumor Cell–Induced Angiogenic Response

    Yaron Carmi;Shahar Dotan;Peleg Rider;Irena Kaplanov

  • Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

    Aya Ludin;Tomer Itkin;Shiri Gur-Cohen;Alexander Mildner

Frequent Co-Authors

Elena Voronov
Elena Voronov Ben-Gurion University of the Negev
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Shraga Segal
Shraga Segal Ben-Gurion University of the Negev
Margot Zöller
Margot Zöller Heidelberg University
Dror Harats
Dror Harats Sheba Medical Center
Mahmoud Huleihel
Mahmoud Huleihel Ben-Gurion University of the Negev
Angel Porgador
Angel Porgador Ben-Gurion University of the Negev
Edna Mozes
Edna Mozes Weizmann Institute of Science
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Roland S. Liblau
Roland S. Liblau Federal University of Toulouse Midi-Pyrénées

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