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D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
42616
World Ranking
6486
National Ranking
3019

Overview

Darryl J. Pappin is affiliated with Cold Spring Harbor Laboratory in the United States. Their research spans multiple topics within biochemistry, genetics, molecular biology, and medicine. The scientist's work primarily focuses on cancer-related molecular mechanisms, RNA research and splicing, RNA modifications in cancer, cellular transport and secretion, peptidase inhibition and analysis, pancreatic and hepatic oncology research, and advanced proteomics techniques and applications.

They have contributed to the fields of biochemistry, genetics, and molecular biology with a total of 37 publications, alongside 15 related to medicine. Their subfields of study include molecular biology, oncology, immunology, cell biology, and cancer research.

Recent papers authored or co-authored by Darryl J. Pappin include:

  • MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression, 2020, Nature Communications
  • HYPERsol: High-Quality Data from Archival FFPE Tissue for Clinical Proteomics, 2020, Journal of Proteome Research
  • PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR, 2021, eLife
  • Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition, 2021, Oncogene
  • Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function, 2024, Science

Throughout their career, Pappin has frequently collaborated with several researchers, including:

  • Keith Rivera
  • David A. Tuveson
  • Paolo Cifani
  • Allen T. Yu
  • David L. Spector

The scientist has published multiple papers in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Proteome Research
  • Scientific Reports
  • The FASEB Journal

Best Publications

  • Probability-based protein identification by searching sequence databases using mass spectrometry data.

    David N. Perkins;Darryl J. C. Pappin;David M. Creasy;John S. Cottrell

  • Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents

    Philip L. Ross;Yulin N. Huang;Jason N. Marchese;Brian Williamson

  • Rapid identification of proteins by peptide-mass fingerprinting

    D.J.C. Pappin;P. Hojrup;A.J. Bleasby

  • Organoid Models of Human and Mouse Ductal Pancreatic Cancer

    Sylvia F. Boj;Chang Il Hwang;Chang Il Hwang;Lindsey A. Baker;Lindsey A. Baker;Iok In Christine Chio;Iok In Christine Chio

  • Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

    Pablo Rodriguez-Viciana;Patricia H Warne;Asim Khwaja;Barbara M Marte

  • Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

    Jihye Yun;Edouard Mullarky;Edouard Mullarky;Changyuan Lu;Kaitlyn N. Bosch

  • Silencing of microRNA families by seed-targeting tiny LNAs.

    Susanna Obad;Camila O dos Santos;Andreas Petri;Markus Heidenblad

  • Proteomics: new perspectives, new biomedical opportunities

    Rosamonde E Banks;Michael J Dunn;Denis F Hochstrasser;Jean-Charles Sanchez

  • MDC1 is required for the intra-S-phase DNA damage checkpoint.

    Michal Goldberg;Manuel Stucki;Jacob Falck;Damien D'Amours

  • Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules

    Yi Zhang;Alejandro Wolf-Yadlin;Phillip L. Ross;Darryl J. Pappin

  • p47 is a cofactor for p97-mediated membrane fusion

    Hisao Kondo;Catherine Rabouille;Richard Newman;Timothy P. Levine

  • A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways.

    Hemmo H Meyer;James G Shorter;Joachim Seemann;Darryl Pappin

  • H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

    Navasona Krishnan;Cexiong Fu;Darryl J. Pappin;Nicholas K. Tonks

  • Identification and preliminary characterization of a protein motif related to the zinc finger.

    Ruth Lovering;Isabel M. Hanson;Katherine L. Borden;Stephen Martin

  • 8-plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease.

    Leila Choe;Mark D'Ascenzo;Norman R. Relkin;Darryl Pappin

  • Cdc2 Kinase Directly Phosphorylates the cis-Golgi Matrix Protein GM130 and Is Required for Golgi Fragmentation in Mitosis

    Martin Lowe;Catherine Rabouille;Nobuhiro Nakamura;Rose Watson

  • Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.

    A. Salmeron;T. B. Ahmad;G. W. Carlile;D. Pappin

  • The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis--preliminary findings.

    Rosamonde E. Banks;Michael J. Dunn;Mary A. Forbes;Anthea Stanley

  • NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

    Iok In Christine Chio;Iok In Christine Chio;Seyed Mehdi Jafarnejad;Mariano Ponz-Sarvise;Mariano Ponz-Sarvise;Youngkyu Park;Youngkyu Park

  • Binding of Inositol Phosphate to DNA-PK and Stimulation of Double-Strand Break Repair

    Leslyn Hanakahi;Michael Bartlet-Jones;Claire Chappell;Darryl Pappin

Frequent Co-Authors

David A. Tuveson
David A. Tuveson Cold Spring Harbor Laboratory
Nicholas K. Tonks
Nicholas K. Tonks Cold Spring Harbor Laboratory
Leemor Joshua-Tor
Leemor Joshua-Tor Cold Spring Harbor Laboratory
Rosamonde E. Banks
Rosamonde E. Banks University of Leeds
Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
David L. Spector
David L. Spector Cold Spring Harbor Laboratory
Peter Selby
Peter Selby University of Leeds
Michael J. Dunn
Michael J. Dunn University College Dublin
Dieter Söll
Dieter Söll Yale University
Gregory J. Hannon
Gregory J. Hannon University of Cambridge

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