World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
51
Citations
17845
World Ranking
2468
National Ranking
1217

Research.com Recognitions

  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2017 - Member of the National Academy of Sciences
  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leemor Joshua-Tor is a researcher affiliated with Cold Spring Harbor Laboratory in the United States. Their work spans across the broad field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology. Their research encompasses several related subfields including Infectious Diseases, Cancer Research, Plant Science, and Immunology.

The main topics addressed in their research include:

  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • MicroRNA in disease regulation
  • SARS-CoV-2 and COVID-19 Research
  • RNA modifications and cancer

Leemor Joshua-Tor has contributed to multiple recent publications across reputable scientific journals. Selected recent papers include:

  • "SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease," 2020, Emerging Microbes & Infections
  • "OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage," 2022, Nature
  • "Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation," 2023, Cell
  • "Evolution of DNA replication origin specification and gene silencing mechanisms," 2020, Nature Communications
  • "The dynamic nature of the human origin recognition complex revealed through five cryoEM structures," 2020, eLife

Their frequent coauthors include:

  • Ankur Garg
  • Jonathan J. Ipsaro
  • Elad Elkayam
  • Dexter W. Adams
  • Lihong Liu

Leemor Joshua-Tor often publishes in specific scientific venues, with multiple publications found in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Communications
  • eLife
  • BIO-PROTOCOL

In recognition of their contributions to science, they have received several awards including:

  • Member of the National Academy of Sciences, 2017
  • Fellow of the American Academy of Arts and Sciences, 2017
  • Fellow of the American Association for the Advancement of Science (AAAS), 2012

Best Publications

  • Argonaute2 Is the Catalytic Engine of Mammalian RNAi

    Jidong Liu;Michelle A. Carmell;Michelle A. Carmell;Fabiola V. Rivas;Carolyn G. Marsden

  • Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity

    Ji-Joon Song;Ji-Joon Song;Stephanie K. Smith;Gregory J. Hannon;Leemor Joshua-Tor;Leemor Joshua-Tor

  • Purified Argonaute2 and an siRNA form recombinant human RISC.

    Fabiola V Rivas;Niraj H Tolia;Niraj H Tolia;Ji-Joon Song;Ji-Joon Song;Juan P Aragon

  • The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

    Ji-Joon Song;Jidong Liu;Niraj H Tolia;Niraj H Tolia;Jonathan Schneiderman

  • Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi

    Erbay Yigit;Pedro J. Batista;Yanxia Bei;Ka Ming Pang

  • Mechanism of DNA translocation in a replicative hexameric helicase

    Eric J. Enemark;Leemor Joshua-Tor

  • The Structure of Human Argonaute-2 in Complex with miR-20a

    Elad Elkayam;Claus-D. Kuhn;Claus-D. Kuhn;Ante Tocilj;Ante Tocilj;Astrid D. Haase

  • Slicer and the Argonautes

    Niraj H Tolia;Leemor Joshua-Tor

  • A triple helix stabilizes the 3′ ends of long noncoding RNAs that lack poly(A) tails

    Jeremy E. Wilusz;Courtney K. JnBaptiste;Laura Y. Lu;Claus D. Kuhn

  • Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum

    Niraj H. Tolia;Niraj H. Tolia;Eric J. Enemark;B. Kim Lee Sim;Leemor Joshua-Tor;Leemor Joshua-Tor

  • The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

    Jonathan J. Ipsaro;Astrid D. Haase;Simon R. Knott;Leemor Joshua-Tor;Leemor Joshua-Tor

  • Strategies for protein coexpression in Escherichia coli.

    Niraj H Tolia;Leemor Joshua-Tor

  • From guide to target: molecular insights into eukaryotic RNA-interference machinery.

    Jonathan J Ipsaro;Leemor Joshua-Tor

  • On Helicases and other motor proteins

    Eric J Enemark;Leemor Joshua-Tor

  • Argonaute slicing is required for heterochromatic silencing and spreading.

    Danielle V. Irvine;Mikel Zaratiegui;Niraj H. Tolia;Derek B. Goto

  • X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus.

    Michael W. Day;Barbara T. Hsu;Leemor Joshua-Tor;Jae-Bum Park

  • Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum.

    Jamie L Schlessman;Deborah Woo;Leemor Joshua-Tor;James B Howard

  • Crystal structure of a conserved protease that binds DNA: The bleomycin hydrolase, Gal6

    L. Joshua-Tor;H. E. Xu;S. A. Johnston;D. C. Rees

  • The Making of a Slicer: Activation of Human Argonaute-1

    Christopher R. Faehnle;Elad Elkayam;Elad Elkayam;Astrid D. Haase;Gregory J. Hannon

  • NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler

    Chen Shen;Jonathan J. Ipsaro;Junwei Shi;Junwei Shi;Joseph P. Milazzo

Frequent Co-Authors

Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Stephen Albert Johnston
Stephen Albert Johnston Arizona State University
Douglas C. Rees
Douglas C. Rees California Institute of Technology
Huilin Li
Huilin Li Van Andel Institute
Robert A. Martienssen
Robert A. Martienssen Cold Spring Harbor Laboratory
Wim Crielaard
Wim Crielaard Academic Center for Dentistry Amsterdam
Klaas J. Hellingwerf
Klaas J. Hellingwerf University of Amsterdam
Nikolaus Grigorieff
Nikolaus Grigorieff Howard Hughes Medical Institute
Darryl J. Pappin
Darryl J. Pappin Cold Spring Harbor Laboratory

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For aspiring molecular biologists, there are a variety of online academic options and career pathways that complement study in this field. Interdisciplinary programs allow students to transition between health science roles and related sectors.

Many students with backgrounds in molecular biology are interested in healthcare professions, such as speech-language pathology. Those without a direct undergraduate major can enroll in an online speech-language pathology prerequisites program to bridge their education and qualify for advanced degrees in this area.

Similarly, if you wish to pursue nursing, online accelerated bsn programs for non nurses offer a fast and flexible route to a Bachelor of Science in Nursing, even for students from non-nursing backgrounds.

After earning a nursing degree, you may consider a specialized career as a psychiatric nurse practitioner. Pay rates can vary by area—see this comprehensive guide to pmhnp salary by state to learn more about earning potential across the U.S. Interested in how quickly you can enter this advanced role? Discover how long does it take to be a nurse practitioner and set your academic goals accordingly.

Best Scientists Citing Leemor Joshua-Tor

Trending Scientists

Recently Published Articles