Thomas Binz mainly investigates Biochemistry, Synaptobrevin, Synaptic vesicle, Cell biology and Neurotoxin. His work investigates the relationship between Biochemistry and topics such as Molecular biology that intersect with problems in Peptide sequence and Proteolysis. The various areas that he examines in his Synaptobrevin study include Synaptic vesicle exocytosis and Syntaxin.
His work in Synaptic vesicle addresses issues such as Vesicle-associated membrane protein, which are connected to fields such as Synaptosome, Proteases, SNAP25, VAMP3 and Lipid bilayer fusion. His work deals with themes such as R-SNARE Proteins, Neurotransmission and Neurotransmitter, which intersect with Cell biology. His work carried out in the field of Neurotoxin brings together such families of science as Toxin and Neuroscience.
His main research concerns Biochemistry, Cell biology, Molecular biology, Synaptobrevin and Neurotoxin. His work on Biochemistry deals in particular with Synaptic vesicle, Toxin, Clostridium botulinum, Binding site and Enzyme. His Cell biology research incorporates elements of Exocytosis, SNARE complex, Neurotransmission, Munc-18 and Transmembrane domain.
His work deals with themes such as Acetylcholine, Clostridium tetani, Peptide sequence and Epitope, Antibody, which intersect with Molecular biology. The concepts of his Synaptobrevin study are interwoven with issues in R-SNARE Proteins, Synaptic vesicle exocytosis, Vesicle fusion, Peptide bond and Syntaxin. His research in Neurotoxin intersects with topics in Nucleic acid sequence, Aplysia and Fusion protein.
Thomas Binz mostly deals with Biochemistry, Cell biology, Enzyme, Molecular biology and Toxin. His work on Synaptobrevin and Binding site as part of general Biochemistry study is frequently linked to Redox, therefore connecting diverse disciplines of science. The Cell biology study combines topics in areas such as In vitro, Mutant, Hsp90, Gene duplication and Thioredoxin.
As a member of one scientific family, he mostly works in the field of Enzyme, focusing on Clostridium botulinum and, on occasion, Recombinant DNA. The study incorporates disciplines such as Cell culture, Tretinoin, Retinoic acid, Neuroblastoma and Botulism in addition to Molecular biology. His Toxin research is multidisciplinary, relying on both Small molecule and Peptide.
His primary scientific interests are in Molecular biology, Toxin, Biochemistry, Protease and Plasma protein binding. His work focuses on many connections between Molecular biology and other disciplines, such as Botulism, that overlap with his field of interest in Cell, Cell culture, Secretion, Synaptobrevin and Bioassay. His Toxin research is mostly focused on the topic Clostridium botulinum.
Gene isoform, Amino acid, Internalization, Membrane protein and Geldanamycin are among the areas of Biochemistry where Thomas Binz concentrates his study. His study in Protease is interdisciplinary in nature, drawing from both Cellular differentiation, Rational design, Apoptosis, Immunoglobulin light chain and Peptide. His Plasma protein binding research is multidisciplinary, incorporating elements of Qb-SNARE Proteins, Mutagenesis, Protein engineering, Protein structure and Binding site.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
Juan Blasi;Juan Blasi;Edwin R. Chapman;Egenhard Link;Thomas Binz.
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.
Tetsuya Hayashi;Harvey McMahon;Shinji Yamasaki;Thomas Binz.
The EMBO Journal (1994)
Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin.
J. Blasi;E.R. Chapman;S. Yamasaki;T. Binz.
The EMBO Journal (1993)
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
Harvey T. McMahon;Yuri A. Ushkaryov;Lambert Edelmann;Egenhard Link.
Proteolysis of SNAP-25 by types E and A botulinal neurotoxins
T. Binz;J. Blasi;S. Yamasaki;A. Baumeister.
Journal of Biological Chemistry (1994)
Tetanus toxin action: Inhibition of neurotransmitter release linked to synaptobrevin proteolysis
Egenhard Link;Lambert Edelmann;Judy H. Chou;Thomas Binz.
Biochemical and Biophysical Research Communications (1992)
The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins.
T Binz;H Kurazono;M Wille;J Frevert.
Journal of Biological Chemistry (1990)
Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity.
Tao Xu;Thomas Binz;Heiner Niemann;Erwin Neher.
Nature Neuroscience (1998)
The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves.
Stefan Mahrhold;Andreas Rummel;Hans Bigalke;Bazbek Davletov.
FEBS Letters (2006)
Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.
T. Hayashi;S. Yamasaki;S. Nauenburg;T. Binz.
The EMBO Journal (1995)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: