Thomas Binz

Overview

Best Publications

• Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

  Juan Blasi;Juan Blasi;Edwin R. Chapman;Egenhard Link;Thomas Binz

  1522
  Citations

• Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

  Tetsuya Hayashi;Harvey McMahon;Shinji Yamasaki;Thomas Binz

  979
  Citations

• Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin.

  J. Blasi;E.R. Chapman;S. Yamasaki;T. Binz

  700
  Citations

• Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein

  Harvey T. McMahon;Yuri A. Ushkaryov;Lambert Edelmann;Egenhard Link

  611
  Citations

• Proteolysis of SNAP-25 by types E and A botulinal neurotoxins

  T. Binz;J. Blasi;S. Yamasaki;A. Baumeister

  536
  Citations

• Tetanus toxin action: Inhibition of neurotransmitter release linked to synaptobrevin proteolysis

  Egenhard Link;Lambert Edelmann;Judy H. Chou;Thomas Binz

  419
  Citations

• The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins.

  T Binz;H Kurazono;M Wille;J Frevert

  389
  Citations

• Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity.

  Tao Xu;Thomas Binz;Heiner Niemann;Erwin Neher

  383
  Citations

• The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves.

  Stefan Mahrhold;Andreas Rummel;Hans Bigalke;Bazbek Davletov

  379
  Citations

• Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

  T. Hayashi;S. Yamasaki;S. Nauenburg;T. Binz

  328
  Citations

• Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin

  S. Yamasaki;A. Baumeister;T. Binz;J. Blasi

  313
  Citations

• Synaptotagmins I and II Act as Nerve Cell Receptors for Botulinum Neurotoxin G

  Andreas Rummel;Tino Karnath;Tina Henke;Hans Bigalke

  298
  Citations

• Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells.

  T Galli;T Chilcote;O Mundigl;T Binz

  291
  Citations

• Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity

  Rongsheng Jin;Andreas Rummel;Thomas Binz;Axel T. Brunger;Axel T. Brunger

  286
  Citations

• The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction

  Andreas Rummel;Stefan Mahrhold;Hans Bigalke;Thomas Binz

  284
  Citations

• Regulation of Releasable Vesicle Pool Sizes by Protein Kinase A-Dependent Phosphorylation of SNAP-25

  Gábor Nagy;Kerstin Reim;Ulf Matti;Nils Brose

  279
  Citations

• Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage.

  Vadakkanchery V Vaidyanathan;Ken‐ichi Yoshino;Michael Jahnz;Christos Dörries

  271
  Citations

• Cell entry strategy of clostridial neurotoxins.

  Thomas Binz;Andreas Rummel

  243
  Citations

• Protein kinase C-dependent phosphorylation of synaptosome-associated protein of 25 kDa at Ser187 potentiates vesicle recruitment.

  Gábor Nagy;Ulf Matti;Ralf B. Nehring;Thomas Binz

  223
  Citations

• Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation‐dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

  Andreas Rummel;Kirstin Häfner;Stefan Mahrhold;Natallia Darashchonak

  208
  Citations