What is he best known for?
The fields of study he is best known for:
Thomas Binz mainly investigates Biochemistry, Synaptobrevin, Synaptic vesicle, Cell biology and Neurotoxin.
His work investigates the relationship between Biochemistry and topics such as Molecular biology that intersect with problems in Peptide sequence and Proteolysis.
The various areas that he examines in his Synaptobrevin study include Synaptic vesicle exocytosis and Syntaxin.
His work in Synaptic vesicle addresses issues such as Vesicle-associated membrane protein, which are connected to fields such as Synaptosome, Proteases, SNAP25, VAMP3 and Lipid bilayer fusion.
His work deals with themes such as R-SNARE Proteins, Neurotransmission and Neurotransmitter, which intersect with Cell biology.
His work carried out in the field of Neurotoxin brings together such families of science as Toxin and Neuroscience.
His most cited work include:
- Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25 (1023 citations)
- Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly. (696 citations)
- Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin. (484 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Biochemistry, Cell biology, Molecular biology, Synaptobrevin and Neurotoxin.
His work on Biochemistry deals in particular with Synaptic vesicle, Toxin, Clostridium botulinum, Binding site and Enzyme.
His Cell biology research incorporates elements of Exocytosis, SNARE complex, Neurotransmission, Munc-18 and Transmembrane domain.
His work deals with themes such as Acetylcholine, Clostridium tetani, Peptide sequence and Epitope, Antibody, which intersect with Molecular biology.
The concepts of his Synaptobrevin study are interwoven with issues in R-SNARE Proteins, Synaptic vesicle exocytosis, Vesicle fusion, Peptide bond and Syntaxin.
His research in Neurotoxin intersects with topics in Nucleic acid sequence, Aplysia and Fusion protein.
He most often published in these fields:
- Biochemistry (51.22%)
- Cell biology (27.64%)
- Molecular biology (22.76%)
What were the highlights of his more recent work (between 2015-2020)?
- Biochemistry (51.22%)
- Cell biology (27.64%)
- Enzyme (8.94%)
In recent papers he was focusing on the following fields of study:
Thomas Binz mostly deals with Biochemistry, Cell biology, Enzyme, Molecular biology and Toxin.
His work on Synaptobrevin and Binding site as part of general Biochemistry study is frequently linked to Redox, therefore connecting diverse disciplines of science.
The Cell biology study combines topics in areas such as In vitro, Mutant, Hsp90, Gene duplication and Thioredoxin.
As a member of one scientific family, he mostly works in the field of Enzyme, focusing on Clostridium botulinum and, on occasion, Recombinant DNA.
The study incorporates disciplines such as Cell culture, Tretinoin, Retinoic acid, Neuroblastoma and Botulism in addition to Molecular biology.
His Toxin research is multidisciplinary, relying on both Small molecule and Peptide.
Between 2015 and 2020, his most popular works were:
- The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain (59 citations)
- Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals (27 citations)
- Identification and Characterization of Botulinum Neurotoxin A Substrate Binding Pockets and Their Re-Engineering for Human SNAP-23 (21 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Molecular biology, Toxin, Biochemistry, Protease and Plasma protein binding.
His work focuses on many connections between Molecular biology and other disciplines, such as Botulism, that overlap with his field of interest in Cell, Cell culture, Secretion, Synaptobrevin and Bioassay.
His Toxin research is mostly focused on the topic Clostridium botulinum.
Gene isoform, Amino acid, Internalization, Membrane protein and Geldanamycin are among the areas of Biochemistry where Thomas Binz concentrates his study.
His study in Protease is interdisciplinary in nature, drawing from both Cellular differentiation, Rational design, Apoptosis, Immunoglobulin light chain and Peptide.
His Plasma protein binding research is multidisciplinary, incorporating elements of Qb-SNARE Proteins, Mutagenesis, Protein engineering, Protein structure and Binding site.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
