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Biology and Biochemistry

D-Index
52
Citations
11136
World Ranking
16590
National Ranking
1308

Overview

Bazbek Davletov is affiliated with the University of Sheffield in the United Kingdom and specializes primarily in the field of Medicine, with a strong focus on Neurology. Their research portfolio includes significant contributions to subfields such as Neurology, Physiology, Psychiatry and Mental Health, Molecular Biology, and Cellular and Molecular Neuroscience.

The scientist's main areas of research revolve around topics including Botulinum Toxin and Related Neurological Disorders, Pain Mechanisms and Treatments, Neurological Disorders and Treatments, Migraine and Headache Studies, Hereditary Neurological Disorders, Cancer Treatment and Pharmacology, and Biochemical and Structural Characterization.

Davletov has published widely in several scientific journals, with frequent contributions appearing in venues such as:

  • Toxicon
  • bioRxiv (Cold Spring Harbor Laboratory)
  • BULLETIN of the L N Gumilyov Eurasian National University BIOSCIENCE Series
  • Neurotherapeutics
  • Life Science Alliance

The scientist has collaborated extensively with other researchers, including:

  • Charlotte Leese
  • Aisha Zhantleuova
  • Altynay Karimova
  • Anna P. Andreou
  • Maria Maiarù

Recent publications by Bazbek Davletov cover various aspects of botulinum toxins and pain treatments. Notable works include:

  • "Double-Binding Botulinum Molecule with Reduced Muscle Paralysis: Evaluation in In Vitro and In Vivo Models of Migraine," 2020, Neurotherapeutics
  • "New botulinum neurotoxin constructs for treatment of chronic pain," 2023, Life Science Alliance
  • "Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay," 2021, Biologicals
  • "Substance P-Botulinum Mediates Long-term Silencing of Pain Pathways that can be Re-instated with a Second Injection of the Construct in Mice," 2024, Journal of Pain
  • "Recent Developments in Engineering Non-Paralytic Botulinum Molecules for Therapeutic Applications," 2024, Toxins

Best Publications

  • Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.

    R.Bryan Sutton;Bazbek A Davletov;Albert M Berghuis;Thomas C Sudhof

  • A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.

    B A Davletov;T C Südhof

  • Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent.

    Ming Zhao;Daniel A. Beauregard;Louiza Loizou;Bazbek Davletov

  • Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling

    Jimmy Z. Zhang;Bazbek A. Davletov;Thomas C. Südhof;Richard G.W. Anderson

  • Bipartite Ca2+-Binding Motif in C2 Domains of Synaptotagmin and Protein Kinase C

    Xuguang Shao;Bazbek A. Davletov;R. Bryan Sutton;Thomas C. Südhof

  • Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3

    Frédéric Darios;Bazbek Davletov

  • The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves.

    Stefan Mahrhold;Andreas Rummel;Hans Bigalke;Bazbek Davletov

  • α-Latrotoxin Receptor, Latrophilin, Is a Novel Member of the Secretin Family of G Protein-coupled Receptors

    Vera G. Lelianova;Bazbek A. Davletov;Alistair Sterling;M. Atiqur Rahman

  • Mutation E46K increases phospholipid binding and assembly into filaments of human α-synuclein

    Woong Choi;Shahin Zibaee;Ross Jakes;Louise C. Serpell

  • Binding of synaptotagmin to the α-latrotoxin receptor implicates both in synaptic vesicle exocytosis

    Alexander G. Petrenko;Mark S. Perin;Bazbek A. Davletov;Yuri A. Ushkaryov

  • Alpha-synuclein, lipids and Parkinson's disease.

    Violeta Ruipérez;Frédéric Darios;Bazbek Davletov

  • Vesicular restriction of synaptobrevin suggests a role for calcium in membrane fusion

    Kuang Hu;Joe Carroll;Sergei Fedorovich;Colin Rickman

  • Interaction of synaptotagmin with the cytoplasmic domains of neurexins

    Yutaka Hata;Bazbek Davletov;Alexander G. Petrenko;Reinhard Jahn

  • Isolation and biochemical characterization of a Ca2+-independent alpha-latrotoxin-binding protein.

    Bazbek A. Davletov;Oleg G. Shamotienko;Vera G. Lelianova;Eugene V. Grishin

  • Beyond BOTOX: advantages and limitations of individual botulinum neurotoxins

    B. Davletov;M. Bajohrs;T. Binz

  • Distinct Ca2+ and Sr2+ Binding Properties of Synaptotagmins: DEFINITION OF CANDIDATE Ca2+ SENSORS FOR THE FAST AND SLOW COMPONENTS OF NEUROTRANSMITTER RELEASE

    Cai Li;Bazbek A. Davletov;Thomas C. Südhof

  • VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission

    Jesica Raingo;Mikhail Khvotchev;Pei Liu;Frederic Darios

  • Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically.

    Bazbek Davletov;Olga Perisic;Roger L. Williams

  • Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis

    Frédéric Darios;Catherine Wasser;Anastasia Shakirzyanova;Artur Giniatullin

  • Vesicle exocytosis stimulated by α‐latrotoxin is mediated by latrophilin and requires both external and stored Ca2+

    B A Davletov;F A Meunier;A C Ashton;H Matsushita

Frequent Co-Authors

Thomas Binz
Thomas Binz Hanover University of Applied Sciences and Arts
Thomas C. Südhof
Thomas C. Südhof Stanford University
Frederic A. Meunier
Frederic A. Meunier University of Queensland
Stephen P. Hunt
Stephen P. Hunt University College London
Rashid Giniatullin
Rashid Giniatullin University of Eastern Finland
Kevin M. Brindle
Kevin M. Brindle University of Cambridge
Robert Zorec
Robert Zorec University of Ljubljana
Ege T. Kavalali
Ege T. Kavalali Vanderbilt University
Giampietro Schiavo
Giampietro Schiavo University College London
Matteo Caleo
Matteo Caleo University of Padua

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