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Microbiology

D-Index
55
Citations
10303
World Ranking
3835
National Ranking
156

Overview

Shunji Kozaki is affiliated with Osaka Metropolitan University in Japan and specializes primarily in the field of Medicine, with a focus on Neurology and related subfields. Their work encompasses Cellular and Molecular Neuroscience, Surgery, Public Health, Environmental and Occupational Health, and Endocrinology.

The research topics that Shunji Kozaki has extensively contributed to include:

  • Botulinum Toxin and Related Neurological Disorders
  • Neurological disorders and treatments
  • Hereditary Neurological Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Nerve Injury and Rehabilitation
  • Streptococcal Infections and Treatments
  • Diphtheria, Corynebacterium, and Tetanus

Kozaki's recent publications demonstrate a strong emphasis on botulinum neurotoxins and their clinical applications, particularly within neurological contexts. Notable papers include:

  • "Translocation domain of botulinum neurotoxin A subtype 2 potently induces entry into neuronal cells," 2020, Microbiology and Immunology
  • "Clinical Safety and Tolerability of A2NTX, a Novel Low Molecular Weight Neurotoxin Derived From Botulinum Toxin Subtype A2, in Comparison with Subtype A1 Toxins," 2021, Preprints.org
  • "Clinical Safety and Tolerability of A2NTX, a Novel Low-Molecular-Weight Neurotoxin Derived from Botulinum Neurotoxin Subtype A2, in Comparison with Subtype A1 Toxins," 2021, Toxins
  • "A Pilot Study of A2NTX, a Novel Low-Molecular-Weight Neurotoxin Derived from Subtype A2 for Post-Stroke Lower Limb Spasticity: Comparison with OnabotulinumtoxinA," 2022, Toxins
  • "Analysis of a plasmid encoding botulinum neurotoxin type G gene in Clostridium argentinense," 2020, Anaerobe

Frequent publication venues for Kozaki include:

  • Toxins
  • Microbiology and Immunology
  • Preprints.org
  • Anaerobe
  • Japanese Journal of Food Microbiology

Kozaki collaborates regularly with several coauthors who contribute to advancing their research themes. These frequent collaborators include Tomoko Kohda, Toshiaki Takeuchi, Ai Miyashiro, Ryosuke Miyamoto, and Yuishin Izumi.

The scientific focus on botulinum toxins and neurological treatments highlights the integration of molecular mechanisms with clinical applications, particularly in addressing neurological disorders and rehabilitation. Kozaki's multidisciplinary approach spans experimental studies in microbiology combined with clinical safety trials, reflecting a bridge between foundational research and therapeutic innovation.

Best Publications

  • An extensive outbreak of staphylococcal food poisoning due to low-fat milk in Japan: estimation of enterotoxin A in the incriminated milk and powdered skim milk.

    T Asao;Y Kumeda;T Kawai;T Shibata

  • Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

    Tomonori Nochi;Yoshikazu Yuki;Haruko Takahashi;Shin Ichi Sawada

  • Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes.

    Tei Ichi Nishiki;Yoichi Kamata;Yasuo Nemoto;Akira Omori

  • Phosphorylation of 25-kDa Synaptosome-associated Protein POSSIBLE INVOLVEMENT IN PROTEIN KINASE C-MEDIATED REGULATION OF NEUROTRANSMITTER RELEASE

    Youji Shimazaki;Tei Ichi Nishiki;Akira Omori;Mariko Sekiguchi

  • The high-affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1a

    Tei Ichi Nishiki;Yoshimi Tokuyama;Yoichi Kamata;Yasuo Nemoto

  • ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle

    Masamitsu Yamamoto;Nobuyuki Marui;Toshiyuki Sakai;Narito Morii

  • A novel M cell-specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses.

    Tomonori Nochi;Yoshikazu Yuki;Akiko Matsumura;Mio Mejima

  • Purification and some properties of Aeromonas hydrophila hemolysin.

    T Asao;Y Kinoshita;S Kozaki;T Uemura

  • Interaction of SNARE Complexes with P/Q-type Calcium Channels in Rat Cerebellar Synaptosomes

    Nicole Martin-Moutot;Nathalie Charvin;Christian Leveque;Kazuki Sato

  • ADP-ribosylation of the rho/rac proteins induces growth inhibition, neurite outgrowth and acetylcholine esterase in cultured PC-12 cells.

    Teiichi Nishiki;Shuh Narumiya;Narito Morii;Masamitsu Yamamoto

  • Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins.

    Shunji Kozaki;Yoichi Kamata;Shinobu Watarai;Tei Ichi Nishiki

  • Nucleotide sequence of the gene encoding Clostridium botulinum neurotoxin type D.

    Thomas Binz;Hisao Kurazono;Michel R. Popoff;Melvin W. Eklund

  • Identification and characterization of functional subunits of Clostridium botulinum type A progenitor toxin involved in binding to intestinal microvilli and erythrocytes.

    Yukako Fujinaga;Kaoru Inoue;Takako Nomura;Junzo Sasaki

  • Binding of Clostridium botulinum Type C and D Neurotoxins to Ganglioside and Phospholipid NOVEL INSIGHTS INTO THE RECEPTOR FOR CLOSTRIDIAL NEUROTOXINS

    Kentaro Tsukamoto;Tomoko Kohda;Masafumi Mukamoto;Kumiko Takeuchi

  • Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice

    Makoto Inoue;Motomasa Kobayashi;Shunji Kozaki;Andreas Zimmer

  • Cytokine-induced enhancement of calcium-dependent glutamate release from astrocytes mediated by nitric oxide

    Tomoaki Ida;Masayuki Hara;Yoichi Nakamura;Shunji Kozaki

  • rho, a Small GTP-Binding Protein, Is Essential for Shigella Invasion of Epithelial Cells

    Masahisa Watarai;Yoichi Kamata;Shunji Kozaki;Chihiro Sasakawa

  • Immunological characterization of papain-induced fragments of Clostridium botulinum type A neurotoxin and interaction of the fragments with brain synaptosomes.

    S Kozaki;A Miki;Y Kamata;J Ogasawara

  • Purification and some properties of progenitor toxins of Clostridium botulinum type B.

    Shunji Kozaki;Sumiko Sakaguchi;Genji Sakaguchi

  • Clostridium botulinum C3 ADP-ribosyltransferase gene. Cloning, sequencing, and expression of a functional protein in Escherichia coli.

    Yasuo Nemoto;Tsunehisa Namba;Shunji Kozaki;Shuh Narumiya

Frequent Co-Authors

Hiroshi Kiyono
Hiroshi Kiyono University of Tokyo
Masami Takahashi
Masami Takahashi Kitasato University
Yoshikazu Yuki
Yoshikazu Yuki University of Tokyo
Tomonori Nochi
Tomonori Nochi Tohoku University
Shuh Narumiya
Shuh Narumiya Kyoto University
Hideo Tsukada
Hideo Tsukada Hamamatsu Photonics (Japan)
Min Yao
Min Yao Hokkaido University
Heiner Niemann
Heiner Niemann Friedrich-Loeffler-Institut
Yoshikazu Tanaka
Yoshikazu Tanaka Tohoku University
Kazunari Akiyoshi
Kazunari Akiyoshi Kyoto University

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Related Online Degrees & Career Pathways

Studying Microbiology in the USA opens doors to numerous healthcare and administrative roles. For those interested in clinical practice, exploring functional medicine nurse practitioner programs can provide specialized training focused on holistic patient care, blending microbiology insights with personalized treatment approaches.

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For those heading towards healthcare management, an understanding of clinical data combined with microbiology knowledge can lead to success as a Health Information Manager. You can learn more about this career, including health information manager salary and responsibilities, to evaluate if this path fits your goals.

If you want to pursue this field, consider enrolling in an online CAHIIM accredited health information management degree. These programs offer flexible learning opportunities while meeting industry standards for healthcare data management careers.

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