2012 - Fellow of the Royal Society of Edinburgh
Fellow of The Academy of Medical Sciences, United Kingdom
Owen J. Sansom mainly investigates Cancer research, Cell biology, Stem cell, Carcinogenesis and Signal transduction. His research integrates issues of Cell culture, Pancreatic cancer, Immunology, Metastasis and PI3K/AKT/mTOR pathway in his study of Cancer research. His Immunology research includes themes of Cancer and Colorectal cancer.
His Cell biology study integrates concerns from other disciplines, such as Cell, Integrin, Cell cycle, Cellular differentiation and Cancer cell. His study in Stem cell is interdisciplinary in nature, drawing from both Adenomatous polyposis coli and Adult stem cell. As a member of one scientific family, Owen J. Sansom mostly works in the field of Carcinogenesis, focusing on Protein kinase B and, on occasion, Oncogene.
Owen J. Sansom spends much of his time researching Cancer research, Cell biology, Wnt signaling pathway, Carcinogenesis and Stem cell. His studies deal with areas such as Cancer, Colorectal cancer, Pancreatic cancer, Immunology and Signal transduction as well as Cancer research. His Pancreatic cancer study combines topics from a wide range of disciplines, such as KRAS, Metastasis, Pancreas and Pathology.
His Cell biology study combines topics in areas such as Cancer cell, Cell and Cellular differentiation. He has included themes like Molecular biology, Adenomatous polyposis coli and Intestinal epithelium in his Wnt signaling pathway study. His study explores the link between Carcinogenesis and topics such as Apoptosis that cross with problems in In vivo.
His scientific interests lie mostly in Cancer research, Cell biology, Wnt signaling pathway, Colorectal cancer and Stem cell. His Cancer research research incorporates elements of Carcinogenesis, Cancer, Pancreatic cancer, Cell growth and Downregulation and upregulation. The study incorporates disciplines such as Metabolism and Protein biosynthesis in addition to Cell biology.
His Wnt signaling pathway research is multidisciplinary, incorporating perspectives in Cancer stem cell, Homeostasis and MAPK/ERK pathway. His Colorectal cancer research incorporates themes from Epidermal growth factor receptor, Oncology and Phosphorylation. The Stem cell study which covers Tissue homeostasis that intersects with RALA.
His main research concerns Cancer research, Pancreatic cancer, Cell biology, Cancer and Cell growth. His Cancer research research integrates issues from Hypoxia, Transcriptome, Downregulation and upregulation, Metastasis and Regeneration. The concepts of his Pancreatic cancer study are interwoven with issues in Phenotype, Reverse phase protein lysate microarray, Combination therapy and Immunotherapy.
His Cell biology research is multidisciplinary, incorporating elements of Regulation of gene expression and Protein biosynthesis. As part of the same scientific family, Owen J. Sansom usually focuses on Cancer, concentrating on Pancreas and intersecting with Blocking antibody and Survival rate. His Cell growth research is multidisciplinary, relying on both Gemcitabine and Cell.
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Crypt stem cells as the cells-of-origin of intestinal cancer
Nick Barker;Rachel A. Ridgway;Johan H. Van Es;Marc Van De Wetering.
Nature (2009)
Genomic analyses identify molecular subtypes of pancreatic cancer
Bailey P;Chang Dk;Nones K;Nones K;Johns Al.
Nature (2016)
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
Ulrich Wellner;Jörg Schubert;Ulrike C Burk;Otto Schmalhofer.
Nature Cell Biology (2009)
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
Juan Carlos Acosta;Ana Banito;Torsten Wuestefeld;Athena Georgilis.
Nature Cell Biology (2013)
Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
Sarah Schwitalla;Alexander A. Fingerle;Patrizia Cammareri;Tim Nebelsiek.
Cell (2013)
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.
Owen J. Sansom;Karen Reed;Anthony Joseph Hayes;Heather Ireland.
Genes & Development (2004)
Mutant p53 Drives Invasion by Promoting Integrin Recycling
Patricia A.J. Muller;Patrick T. Caswell;Brendan Doyle;Marcin P. Iwanicki.
Cell (2009)
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
Luke Boulter;Olivier Govaere;Tom G Bird;Sorina Radulescu.
Nature Medicine (2012)
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers
Javier Muñoz;Daniel E Stange;Arnout G Schepers;Marc van de Wetering.
The EMBO Journal (2012)
Myc deletion rescues Apc deficiency in the small intestine
Owen J. Sansom;Valerie Meniel;Vanesa Muncan;Toby Phesse.
Nature (2007)
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