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Molecular Biology

D-Index
49
Citations
9552
World Ranking
2628
National Ranking
66

Overview

Michal Mokry is a researcher affiliated with Utrecht University in the Netherlands. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these domains, Mokry has contributed extensively to subfields such as Immunology, Molecular Biology, Cardiology and Cardiovascular Medicine, Genetics, and Cancer Research.

Their research topics include Atherosclerosis and Cardiovascular Diseases, Single-cell and spatial transcriptomics, Immune cells in cancer, Cardiovascular Disease and Adiposity, Genetic Associations and Epidemiology, Congenital heart defects research, and Cell Adhesion Molecules Research.

Michal Mokry has published numerous articles, including recent significant papers:

  • Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics (2020, Circulation Research)
  • Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis (2020, Circulation)
  • Prime editing for functional repair in patient-derived disease models (2020, Nature Communications)
  • Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification (2023, Nature Genetics)
  • Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching (2021, Circulation)

Frequent co-authors with whom Mokry has collaborated include Gerard Pasterkamp, Hester M. den Ruijter, Sander W. van der Laan, Dominique P.V. de Kleijn, and Ernest Diez Benavente.

Their publications appear regularly in scientific venues such as bioRxiv (Cold Spring Harbor Laboratory), Atherosclerosis, European Heart Journal, Circulation, and Scientific Reports.

Best Publications

  • Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

    Caroline A. Lindemans;Caroline A. Lindemans;Marco Calafiore;Anna M. Mertelsmann;Margaret H. O'Connor

  • Tissue-specific mutation accumulation in human adult stem cells during life

    Francis Blokzijl;Joep de Ligt;Myrthe Jager;Valentina Sasselli

  • Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

    Marie A.C. Depuydt;Koen H.M. Prange;Lotte Slenders;Tiit Örd

  • Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location-Specific Function

    Sabine Middendorp;Kerstin Schneeberger;Caroline L Wiegerinck;Michal Mokry

  • Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.

    Gabriel F. Alencar;Katherine M. Owsiany;Santosh Karnewar;Katyayani Sukhavasi

  • Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts

    Jurian Schuijers;Jan Philipp Junker;Michal Mokry;Pantelis Hatzis

  • Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand

    Sylvia F. Boj;Johan H. van Es;Meritxell Huch;Vivian S.W. Li

  • Canonical Wnt signaling negatively modulates regulatory T cell function

    Jorg van Loosdregt;Veerle Fleskens;Machteld M. Tiemessen;Michal Mokry

  • Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

    Renée R C E Schreurs;Martin E Baumdick;Adrian F Sagebiel;Max Kaufmann

  • Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

    Jurian Schuijers;Michal Mokry;Pantelis Hatzis;Edwin Cuppen

  • Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

    Jodie Ouahed;Elizabeth Spencer;Daniel Kotlarz;Dror S Shouval

  • Prime editing for functional repair in patient-derived disease models

    Imre F. Schene;Indi P. Joore;Rurika Oka;Michal Mokry

  • Primary Colorectal Cancers and Their Subsequent Hepatic Metastases Are Genetically Different: Implications for Selection of Patients for Targeted Treatment

    Joost S. Vermaat;Isaac J. Nijman;Marco J. Koudijs;Frank L. Gerritse

  • Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.

    Astrid Eijkelenboom;Michal Mokry;Elzo de Wit;Lydia M Smits

  • An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming

    Marcia A. M. M. Ferraz;Hoon Suk Rho;Daiane Hemerich;Daiane Hemerich;Heiko H. W. Henning

  • E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

    Bart Westendorp;Michal Mokry;Marian J.A. Groot Koerkamp;Frank C.P. Holstege

  • PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation

    Alessandra Petrelli;Gerdien Mijnheer;David P. Hoytema van Konijnenburg;David P. Hoytema van Konijnenburg;Maria M. van der Wal

  • Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium.

    Michal Mokry;Sabine Middendorp;Caroline L. Wiegerinck;Merlijn Witte

  • Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression

    Janneke G.C. Peeters;Stephin J. Vervoort;Sander C. Tan;Gerdien Mijnheer

  • Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

    Michal Mokry;Harma Feitsma;Isaac J. Nijman;Ewart de Bruijn

Frequent Co-Authors

Edward E. S. Nieuwenhuis
Edward E. S. Nieuwenhuis Utrecht University
Edwin Cuppen
Edwin Cuppen Utrecht University
Gerard Pasterkamp
Gerard Pasterkamp Utrecht University
Paul J. Coffer
Paul J. Coffer Utrecht University
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Isaac J. Nijman
Isaac J. Nijman Utrecht University
Dirk J. Duncker
Dirk J. Duncker Erasmus University Rotterdam
Alain de Bruin
Alain de Bruin Utrecht University
Johan Kuiper
Johan Kuiper Leiden University

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