D-Index & Metrics Best Publications
Edward E. S. Nieuwenhuis

Edward E. S. Nieuwenhuis

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 48 Citations 13,920 96 World Ranking 3529 National Ranking 117

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Immune system

His primary areas of investigation include Immunology, Stem cell, Organoid, Immune system and Cytokine. The study incorporates disciplines such as Stimulation and Intestinal mucosa in addition to Immunology. His Stimulation research integrates issues from Oxazolone, Pathogenesis, Ulcerative colitis, T-cell receptor and Interleukin 13.

His Intestinal mucosa research is multidisciplinary, incorporating perspectives in Paneth cell and Inflammatory bowel disease. His research integrates issues of LGR5 and Cellular differentiation, Adult stem cell in his study of Stem cell. His Organoid research is multidisciplinary, relying on both Molecular biology, Cystic fibrosis and Intestinal epithelium.

His most cited work include:

  • XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease (1033 citations)
  • Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients (871 citations)
  • Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver (666 citations)

What are the main themes of his work throughout his whole career to date?

Edward E. S. Nieuwenhuis spends much of his time researching Immunology, Immune system, Cell biology, Internal medicine and Organoid. His biological study spans a wide range of topics, including Intestinal mucosa and Inflammatory bowel disease. As a part of the same scientific study, Edward E. S. Nieuwenhuis usually deals with the Inflammatory bowel disease, concentrating on Ulcerative colitis and frequently concerns with Colitis.

His studies deal with areas such as Cytokine and Microbiology as well as Immune system. His Internal medicine study incorporates themes from Gastroenterology and Endocrinology. His Organoid study which covers Stem cell that intersects with Cellular differentiation.

He most often published in these fields:

  • Immunology (41.87%)
  • Immune system (28.75%)
  • Cell biology (13.75%)

What were the highlights of his more recent work (between 2018-2021)?

  • Organoid (14.38%)
  • Computational biology (8.75%)
  • Gene (9.38%)

In recent papers he was focusing on the following fields of study:

Edward E. S. Nieuwenhuis mostly deals with Organoid, Computational biology, Gene, Prime and Immune system. Edward E. S. Nieuwenhuis combines subjects such as Less invasive, Clinical trial, MEDLINE, Mutation and Intervention with his study of Organoid. The various areas that Edward E. S. Nieuwenhuis examines in his Immune system study include Psychological intervention, Incidence, Cytokine and Etiology.

Edward E. S. Nieuwenhuis has researched Cytokine in several fields, including T cell migration and T cell chemotaxis. His T cell study contributes to a more complete understanding of Immunology. As part of one scientific family, Edward E. S. Nieuwenhuis deals mainly with the area of Tumor necrosis factor alpha, narrowing it down to issues related to the Stem cell, and often Stimulation, Lipotoxicity and Unfolded protein response.

Between 2018 and 2021, his most popular works were:

  • Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life (51 citations)
  • Prime editing for functional repair in patient-derived disease models (21 citations)
  • Prime editing for functional repair in patient-derived disease models (21 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Immune system

His scientific interests lie mostly in Computational biology, Gene, Immune system, Pediatrics and Homology directed repair. His Computational biology research is multidisciplinary, incorporating elements of Enhancer, Transcription factor, Epigenetics, Noncoding DNA and Candidate gene. His research in Immune system intersects with topics in Tumor necrosis factor alpha, Incidence, Inflammatory bowel disease and Etiology.

His studies deal with areas such as Very early onset, Young adult and Psychological intervention as well as Pediatrics. His Homology directed repair research spans across into fields like Genome editing, HEK 293 cells, Organoid, Mutation and Adult stem cell. Edward E. S. Nieuwenhuis integrates Genome editing and Prime in his research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

Arthur Kaser;Ann-Hwee Lee;Andre Franke;Jonathan N. Glickman.
Cell (2008)

1426 Citations

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

Gerald Schwank;Bon Kyoung Koo;Valentina Sasselli;Johanna F. Dekkers.
Cell Stem Cell (2013)

1339 Citations

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch;Helmuth Gehart;Ruben van Boxtel;Karien Hamer.
Cell (2015)

1082 Citations

Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells.

Frank Heller;Ivan J Fuss;Edward E Nieuwenhuis;Edward E Nieuwenhuis;Richard S Blumberg.
Immunity (2002)

873 Citations

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Johanna F Dekkers;Caroline L Wiegerinck;Hugo R de Jonge;Inez Bronsveld.
Nature Medicine (2013)

822 Citations

The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease

M.F. Neurath;B. Weigmann;S. Finotto;J. Glickman.
Journal of Experimental Medicine (2002)

744 Citations

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

Caroline A. Lindemans;Caroline A. Lindemans;Marco Calafiore;Anna M. Mertelsmann;Margaret H. O'Connor.
Nature (2015)

740 Citations

Tissue-specific mutation accumulation in human adult stem cells during life

Francis Blokzijl;Joep de Ligt;Myrthe Jager;Valentina Sasselli.
Nature (2016)

686 Citations

CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung

Edward E.S. Nieuwenhuis;Tetsuya Matsumoto;Mark Exley;Robbert A. Schleipman.
Nature Medicine (2002)

368 Citations

Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis.

Leonie A Boven;Marjan Van Meurs;Marloes Van Zwam;Annet Wierenga-Wolf.
Brain (2006)

361 Citations

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