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Luc J. W. van der Laan

Luc J. W. van der Laan

D-Index & Metrics

Molecular Biology

D-Index
66
Citations
25015
World Ranking
1599
National Ranking
43

Medicine

D-Index
72
Citations
27444
World Ranking
19766
National Ranking
722

Overview

Luc J. W. van der Laan is affiliated with Erasmus University Rotterdam in the Netherlands. Their research primarily spans the field of Medicine with a significant focus on Surgery, Hepatology, Molecular Biology, Oncology, and Epidemiology. The scientist's work addresses several topics related to liver function, disease, and transplantation.

The main topics covered in their research include:

  • Liver physiology and pathology
  • Organ Transplantation Techniques and Outcomes
  • Pediatric Hepatobiliary Diseases and Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Liver Disease Diagnosis and Treatment
  • Tissue Engineering and Regenerative Medicine
  • Liver Disease and Transplantation

Van der Laan has contributed to scholarly work published largely in biomedical and clinical journals. Frequent publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Transplantation
  • Journal of Hepatology
  • Cells
  • Scientific Reports

Collaborative research is a significant part of their academic activity. Frequent co-authors include:

  • Monique M.A. Verstegen
  • Henk P. Roest
  • Maikel P. Peppelenbosch
  • Qiuwei Pan
  • Jeroen de Jonge

Among recent publications, several notable papers have contributed to the fields of organoids, liver research, and cancer biology. Selected recent papers are:

  • "Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids," 2021, published in Cell Stem Cell
  • "Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver-Like Metabolic Biofactories," 2022, published in Advanced Materials
  • "The extracellular matrix as hallmark of cancer and metastasis: From biomechanics to therapeutic targets," 2024, published in Science Translational Medicine
  • "Prime editing for functional repair in patient-derived disease models," 2020, published in Nature Communications
  • "Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance," 2020, published in Cellular and Molecular Gastroenterology and Hepatology

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

    Meritxell Huch;Helmuth Gehart;Ruben van Boxtel;Karien Hamer

  • Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

    Laura Broutier;Gianmarco Mastrogiovanni;Monique M.A. Verstegen;Hayley E. Francies

  • Tissue-specific mutation accumulation in human adult stem cells during life

    Francis Blokzijl;Joep de Ligt;Myrthe Jager;Valentina Sasselli

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

    Vedashree Ramakrishnaiah;Christine Thumann;Isabel Fofana;Francois Habersetzer

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The macrophage receptor MARCO.

    Georg Kraal;Luc J.W van der Laan;Outi Elomaa;Karl Tryggvason

  • Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-α and nitric oxide

    Luc J.W. van der Laan;Sigrid R. Ruuls;Kimberley S. Weber;Ilse J. Lodder

  • Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

    Ary Marsee;Floris J M Roos;Monique M A Verstegen

  • Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

    Zhan Su;Amy Strange;Claire Palles

  • Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi)

    Qiuwei Pan;Vedashree Ramakrishnaiah;Scot Henry;Scot Henry;Suomi Fouraschen

  • Prime editing for functional repair in patient-derived disease models

    Imre F. Schene;Indi P. Joore;Rurika Oka;Michal Mokry

  • Modeling rotavirus infection and antiviral therapy using primary intestinal organoids.

    Yuebang Yin;Marcel Bijvelds;Wen Dang;Lei Xu

  • Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells

    Anthony J. Pelletier;Luc J. W. van der Laan;Patrick Hildbrand;Michael A. Siani

  • Detection of spontaneous tumorigenic transformation during culture expansion of human mesenchymal stromal cells.

    Qiuwei Pan;Suomi M G Fouraschen;Petra E de Ruiter;Winand N M Dinjens

  • Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance

    Jiaye Liu;Pengfei Li;Ling Wang;Meng Li

  • Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting?

    Ahmet Demirkiran;Thijs K. Hendrikx;Carla C. Baan;Luc J. W. van der Laan

  • Secreted Factors of Human Liver-Derived Mesenchymal Stem Cells Promote Liver Regeneration Early After Partial Hepatectomy

    Suomi M.G. Fouraschen;Qiuwei Pan;Petra E. de Ruiter;Waqar R.R. Farid

  • Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett's Esophagus

    Claire Palles;Laura Chegwidden;Xinzhong Li;John M. Findlay

Frequent Co-Authors

Hugo W. Tilanus
Hugo W. Tilanus Erasmus University Rotterdam
Jan N. M. IJzermans
Jan N. M. IJzermans Erasmus University Rotterdam
Maikel P. Peppelenbosch
Maikel P. Peppelenbosch Erasmus University Rotterdam
Harry L.A. Janssen
Harry L.A. Janssen Erasmus University Rotterdam
Carla C. Baan
Carla C. Baan Erasmus University Rotterdam
Ernst J. Kuipers
Ernst J. Kuipers Nanyang Technological University
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Martin J. Hoogduijn
Martin J. Hoogduijn Erasmus University Rotterdam
Evelina Gatti
Evelina Gatti Aix-Marseille University
Edward E. S. Nieuwenhuis
Edward E. S. Nieuwenhuis Utrecht University

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