What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Internal medicine
Toshiro Sato mostly deals with Stem cell, Adult stem cell, LGR5, Cell biology and Endothelial stem cell.
He combines subjects such as Wnt signaling pathway, Cellular differentiation, Stem cell transplantation for articular cartilage repair and Pathology with his study of Stem cell.
His LGR5 research is multidisciplinary, incorporating elements of Lineage tracing, Multipotent Stem Cell, Immunology, Organoid and Cell lineage.
His research in Immunology intersects with topics in Crypt, Paneth cell and Macrophage.
His Organoid research incorporates themes from Regulation of gene expression, Internal medicine, Transplantation and Cancer research.
His Cell biology research focuses on Progenitor cell in particular.
His most cited work include:
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche (3425 citations)
- Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. (1680 citations)
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts (1579 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Cell biology, Stem cell, Organoid, Immunology and LGR5.
His Cell biology research is multidisciplinary, incorporating perspectives in Crypt, Paneth cell and Cellular differentiation.
His Stem cell study incorporates themes from Pathology, Intestinal epithelium, Regeneration and Adult stem cell.
His work deals with themes such as Epithelium, Cancer research, Cell culture, CRISPR and Transplantation, which intersect with Organoid.
His work is dedicated to discovering how Immunology, Lamina propria are connected with Intestinal mucosa and other disciplines.
His study in LGR5 is interdisciplinary in nature, drawing from both Multipotent Stem Cell, Molecular biology, Small intestine and Transgene.
He most often published in these fields:
- Cell biology (35.36%)
- Stem cell (35.91%)
- Organoid (31.49%)
What were the highlights of his more recent work (between 2018-2021)?
- Organoid (31.49%)
- Cell biology (35.36%)
- Stem cell (35.91%)
In recent papers he was focusing on the following fields of study:
Organoid, Cell biology, Stem cell, Immunology and Immune system are his primary areas of study.
The Organoid study combines topics in areas such as Cancer research, Phenotype, Intestinal epithelium, Pathology and LGR5.
As a member of one scientific family, he mostly works in the field of Intestinal epithelium, focusing on Paneth cell and, on occasion, Transcriptional regulation.
Toshiro Sato has researched Cell biology in several fields, including Epithelium and Crypt.
His study brings together the fields of Computational biology and Stem cell.
The concepts of his Immunology study are interwoven with issues in Transmission and Primary sclerosing cholangitis.
Between 2018 and 2021, his most popular works were:
- Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis (71 citations)
- Somatic inflammatory gene mutations in human ulcerative colitis epithelium. (47 citations)
- Modeling Human Digestive Diseases With CRISPR-Cas9–Modified Organoids (41 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cancer
- Internal medicine
Toshiro Sato spends much of his time researching Organoid, Cancer research, Phenotype, Stem cell and Computational biology.
His research brings together the fields of Fusion gene and Organoid.
Toshiro Sato interconnects Mutation, Interleukin, Interleukin 13 and Colorectal cancer in the investigation of issues within Cancer research.
The study incorporates disciplines such as Noggin, LGR5 and Transgene in addition to Mutation.
His research integrates issues of Cancer and CRISPR in his study of Phenotype.
His Stem cell research includes themes of Disease and Epithelial tissue.
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