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Immunology

D-Index
70
Citations
24609
World Ranking
2377
National Ranking
1137

Overview

Nobuhiko Kamada is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology with a strong emphasis on subfields such as molecular biology, immunology, infectious diseases, genetics, and periodontics.

Their scholarly contributions address several main topics in health and microbiology. Key areas include gut microbiota and health, Clostridium difficile and Clostridium perfringens research, inflammatory bowel disease, oral microbiology and periodontitis research, probiotics and fermented foods, microscopic colitis, and eosinophilic esophagitis.

Recent publications authored or coauthored by Nobuhiko Kamada highlight investigations at the intersection of the oral cavity and gut health, as well as immunological modulation using advanced biomedical materials. Notable publications include:

  • "The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis" (2020, Cell)
  • "The Bacterial Connection between the Oral Cavity and the Gut Diseases" (2020, Journal of Dental Research)
  • "Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel" (2021, Nature Biomedical Engineering)
  • "Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota" (2020, Nature Medicine)
  • "Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome" (2021, Advanced Drug Delivery Reviews)

Kamada frequently collaborates with researchers such as Sho Kitamoto, Shrinivas Bishu, Hiroko Nagao-Kitamoto, Kohei Sugihara, and John Y. Kao. These partnerships have resulted in multiple publications, reflecting sustained research relationships within their scientific community.

Key venues where Nobuhiko Kamada has published include bioRxiv (Cold Spring Harbor Laboratory), Gastroenterology, JCI Insight, Inflammatory Bowel Diseases, and Science Immunology. These venues demonstrate their involvement in both preprint dissemination and peer-reviewed medical and immunological research journals.

Best Publications

  • A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

    Mahesh S. Desai;Mahesh S. Desai;Anna M. Seekatz;Nicole M. Koropatkin;Nobuhiko Kamada

  • Role of the gut microbiota in immunity and inflammatory disease

    Nobuhiko Kamada;Sang Uk Seo;Grace Y. Chen;Gabriel Núñez

  • Control of pathogens and pathobionts by the gut microbiota.

    Nobuhiko Kamada;Grace Y Chen;Naohiro Inohara;Gabriel Núñez

  • Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

    Koji Atarashi;Takeshi Tanoue;Minoru Ando;Nobuhiko Kamada

  • Unique CD14+ intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis

    Nobuhiko Kamada;Tadakazu Hisamatsu;Susumu Okamoto;Hiroshi Chinen

  • IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn’s disease

    Taku Kobayashi;Susumu Okamoto;Tadakazu Hisamatsu;Nobuhiko Kamada

  • Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis

    Yonghyun Lee;Kohei Sugihara;Merritt G. Gillilland;Sangyong Jon

  • The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.

    Sho Kitamoto;Hiroko Nagao-Kitamoto;Yizu Jiao;Merritt G. Gillilland

  • NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense.

    Luigi Franchi;Nobuhiko Kamada;Yuumi Nakamura;Aaron Burberry

  • Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

    Michael H. Shaw;Nobuhiko Kamada;Yun-Gi Kim;Guillermo Gabriel Nuñez

  • Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development

    Yong Soo Lee;Tae Young Kim;Yeji Kim;Su Hyun Lee

  • Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

    Nobuhiro Nakamoto;Nobuo Sasaki;Nobuo Sasaki;Ryo Aoki;Ryo Aoki;Kentaro Miyamoto

  • Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease.

    Hiromasa Takaishi;Takahiro Matsuki;Atsushi Nakazawa;Toshihiko Takada

  • A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice

    Atsushi Hayashi;Toshiro Sato;Nobuhiko Kamada;Yohei Mikami

  • The Bacterial Connection between the Oral Cavity and the Gut Diseases.

    S. Kitamoto;H. Nagao-Kitamoto;R. Hein;T.M. Schmidt

  • Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

    Sang Uk Seo;Nobuhiko Kamada;Raúl Muñoz-Planillo;Yun Gi Kim

  • Regulation of the Immune System by the Resident Intestinal Bacteria

    Nobuhiko Kamada;Gabriel Núñez

  • Imbalance of NKp44+NKp46− and NKp44−NKp46+ Natural Killer Cells in the Intestinal Mucosa of Patients With Crohn's Disease

    Tetsuro Takayama;Nobuhiko Kamada;Hiroshi Chinen;Susumu Okamoto

  • Abnormally Differentiated Subsets of Intestinal Macrophage Play a Key Role in Th1-Dominant Chronic Colitis through Excess Production of IL-12 and IL-23 in Response to Bacteria

    Nobuhiko Kamada;Tadakazu Hisamatsu;Susumu Okamoto;Toshiro Sato

  • Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.

    Atsushi Sakuraba;Toshiro Sato;Nobuhiko Kamada;Mina Kitazume

  • The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

    Yun Gi Kim;Nobuhiko Kamada;Michael H. Shaw;Neil Warner

Frequent Co-Authors

Toshifumi Hibi
Toshifumi Hibi Kitasato University
Gabriel Núñez
Gabriel Núñez University of Michigan–Ann Arbor
Takanori Kanai
Takanori Kanai Keio University
John Y. Kao
John Y. Kao University of Michigan–Ann Arbor
Toshiro Sato
Toshiro Sato Keio University
Naohiro Inohara
Naohiro Inohara University of Michigan–Ann Arbor
Peter D.R. Higgins
Peter D.R. Higgins University of Michigan–Ann Arbor
Masahira Hattori
Masahira Hattori Waseda University
Kathryn A. Eaton
Kathryn A. Eaton University of Michigan–Ann Arbor
Eric C. Martens
Eric C. Martens University of Michigan–Ann Arbor

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