World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
10992
World Ranking
17062
National Ranking
7035

Research.com Recognitions

  • 2012 - Fellow of Biomaterials Science and Engineering

Overview

John Y. Kao is affiliated with the University of Michigan-Ann Arbor in the United States. Their primary field of study is Medicine, with extensive research contributions spanning Surgery, Molecular Biology, Immunology, Gastroenterology, and Infectious Diseases.

Their research covers multiple main topics, including:

  • Helicobacter pylori-related gastroenterology studies
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Gastrointestinal motility and disorders
  • Gastric Cancer Management and Outcomes
  • Gastroesophageal reflux and treatments
  • Eosinophilic Esophagitis

Frequent coauthors in their work include:

  • Shrinivas Bishu
  • Nobuhiko Kamada
  • Helmut Grasberger
  • Mohamad El-Zaatari
  • Sho Kitamoto

Key venues in which John Y. Kao has published are:

  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Journal of Gastroenterology and Hepatology
  • The American Journal of Gastroenterology

Recent papers authored or coauthored by Kao include:

  • "Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota," 2020, Nature Medicine
  • "DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk," 2021, Journal of Clinical Investigation
  • "Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut," 2023, Immunity
  • "Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation," 2021, Acta Pharmacologica Sinica
  • "Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca 2+ signaling during T cell activation," 2021, Science Signaling

John Y. Kao received the award of Fellow of Biomaterials Science and Engineering in 2012.

Best Publications

  • The gut microbiome in health and in disease

    Andrew B. Shreiner;John Y. Kao;Vincent B. Young

  • Fecal Microbiota Transplant for Treatment of Clostridium difficile Infection in Immunocompromised Patients

    Colleen R. Kelly;Chioma Ihunnah;Monika Fischer;Alexander Khoruts

  • Helicobacter pylori Immune Escape Is Mediated by Dendritic Cell–Induced Treg Skewing and Th17 Suppression in Mice

    John Y. Kao;Min Zhang;Mark J. Miller;Jason C. Mills

  • Association between Helicobacter pylori infection and inflammatory bowel disease: A meta-analysis and systematic review of the literature†

    Jay Luther;Maneesh Dave;Peter D.R. Higgins;John Y. Kao

  • Rifaximin Alters Intestinal Bacteria and Prevents Stress-Induced Gut Inflammation and Visceral Hyperalgesia in Rats

    Dabo Xu;Jun Gao;Merritt Gillilland;Xiaoyin Wu

  • Candida albicans and Bacterial Microbiota Interactions in the Cecum during Recolonization following Broad-Spectrum Antibiotic Therapy

    Katie L. Mason;John R. Erb Downward;Kelly D. Mason;Nicole R. Falkowski

  • Houston Consensus Conference on Testing for Helicobacter pylori Infection in the United States

    Hashem B El-Serag;John Y Kao;Fasiha Kanwal;Mark Gilger

  • Functional Characterization of Inflammatory Bowel Disease–Associated Gut Dysbiosis in Gnotobiotic Mice

    Hiroko Nagao-Kitamoto;Andrew B. Shreiner;Merritt G. Gillilland;Sho Kitamoto

  • Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

    Hiroko Nagao-Kitamoto;Jhansi L. Leslie;Jhansi L. Leslie;Sho Kitamoto;Chunsheng Jin

  • Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis

    Nabeetha A. Nagalingam;John Y. Kao;Vincent B. Young

  • High-dose Dual Therapy Is Superior to Standard First-line or Rescue Therapy for Helicobacter pylori Infection

    Jyh Chin Yang;Chun Jung Lin;Hong Long Wang;Jin De Chen

  • Dual biological effects of the cytokines interleukin-10 and interferon-γ.

    Cailin Moira Wilke;Shuang Wei;Lin Wang;Lin Wang;Ilona Kryczek

  • Interleukin-10 ablation promotes tumor development, growth, and metastasis

    Takashi Tanikawa;Cailin Moira Wilke;Ilona Kryczek;Grace Y. Chen

  • Association between Helicobacter pylori and Barrett's esophagus, erosive esophagitis, and gastroesophageal reflux symptoms.

    Joel H. Rubenstein;Joel H. Rubenstein;John M. Inadomi;James Scheiman;Philip Schoenfeld;Philip Schoenfeld

  • Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma

    Yana Zavros;Kathryn A Eaton;Weiqun Kang;Sivaprakash Rathinavelu

  • Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent Clostridium difficile infection.

    Anna M. Seekatz;Casey M. Theriot;Krishna Rao;Yu-Ming Chang

  • Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice.

    Yundong Sun;Yundong Sun;Min Zhang;Chun–Chia Chen;Chun–Chia Chen;Merritt Gillilland

  • Intestinal dysbiosis in inflammatory bowel disease.

    Nirmal Kaur;Chun Chia Chen;Jay Luther;John Y. Kao

  • Overview of Gut Immunology

    Katie Lynn Mason;Gary B. Huffnagle;Mairi C. Noverr;John Y. Kao

  • The Role of Dendritic Cells in the Development of Acute Dextran Sulfate Sodium Colitis

    Bradford E. Berndt;Min Zhang;Gwo Hsiao Chen;Gary B. Huffnagle

Frequent Co-Authors

Nobuhiko Kamada
Nobuhiko Kamada University of Michigan–Ann Arbor
Juanita L. Merchant
Juanita L. Merchant University of Arizona
Kathryn A. Eaton
Kathryn A. Eaton University of Michigan–Ann Arbor
Vincent B. Young
Vincent B. Young University of Michigan–Ann Arbor
Peter D.R. Higgins
Peter D.R. Higgins University of Michigan–Ann Arbor
Chung Owyang
Chung Owyang University of Michigan–Ann Arbor
Gary B. Huffnagle
Gary B. Huffnagle University of Michigan–Ann Arbor
Weiping Zou
Weiping Zou University of Michigan–Ann Arbor
Deborah L. Gumucio
Deborah L. Gumucio University of Michigan–Ann Arbor
John M. Inadomi
John M. Inadomi University of Utah

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