World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
16701
World Ranking
11774
National Ranking
5064

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Deborah L. Gumucio is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily falls within the field of Biochemistry, Genetics, and Molecular Biology, with a focus on molecular biology, cell biology, pathology and forensic medicine, developmental neuroscience, and hepatology.

The scientist's work addresses a range of topics including epigenetics and DNA methylation, Hedgehog signaling pathway studies, tumors and oncological cases, biotin and related studies, cellular transport and secretion, cellular mechanics and interactions, and pluripotent stem cells research.

Recent publications by Deborah L. Gumucio include:

  • Hedgehog Signaling in Intestinal Development and Homeostasis, 2020, Annual Review of Physiology
  • Spatially resolved cell polarity proteomics of a human epiblast model, 2021, Science Advances
  • Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells, 2020, Frontiers in Cell and Developmental Biology
  • RYK-mediated filopodial pathfinding facilitates midgut elongation, 2020, Development
  • Faculty Opinions recommendation of Liver homeostasis is maintained by midlobular zone 2 hepatocytes, 2021, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

Frequent collaborators include Jason R. Spence, Katherine D. Walton, Chari L. Cortez, K Taniguchi, and Sicong Wang. These collaborations have contributed to multiple publications.

Deborah L. Gumucio has published several papers in notable journals such as Academic Medicine, Annual Review of Physiology, Science Advances, Frontiers in Cell and Developmental Biology, and Development.

In recognition of scientific contributions, Deborah L. Gumucio was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever

    I. Aksentijevich;M. Centola;Z. M. Deng;R. Sood

  • Epithelial NEMO links innate immunity to chronic intestinal inflammation

    Arianna Nenci;Christoph Becker;Andy Wullaert;Ralph Gareus

  • Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The International FMF Consortium.

    N Zaks;JE Balow;E Mansfield;M. E. Mangelsdorf

  • cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine

    Blair B. Madison;Laura Dunbar;XiaoTan T. Qiao;Katherine A. Braunstein

  • Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.

    Daniel L. Worthley;Michael Churchill;Jocelyn T. Compton;Yagnesh Tailor

  • Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

    Kelli L. VanDussen;Alexis J. Carulli;Theresa M. Keeley;Sanjeevkumar R. Patel

  • Controlled modelling of human epiblast and amnion development using stem cells.

    Yi Zheng;Xufeng Xue;Yue Shao;Sicong Wang

  • Epithelial hedgehog signals pattern the intestinal crypt-villus axis.

    Blair B. Madison;Katherine Braunstein;Erlene Kuizon;Kathleen Portman

  • Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis.

    Neil Richards;Philip Schaner;Arturo Diaz;Jeanne Stuckey

  • Locus control regions of mammalian β-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

    Ross Hardison;Jerry L. Slightom;Deborah L. Gumucio;Morris Goodman

  • ASC is an activating adaptor for NF-κB and caspase-8-dependent apoptosis

    Junya Masumoto;Theresa A Dowds;Philip Schaner;Felicia F Chen

  • Peroxisome proliferator activated receptor γ in colonic epithelial cells protects against experimental inflammatory bowel disease

    Masahiro Adachi;Reiko Kurotani;Keiichiro Morimura;Yatrik Shah

  • A pluripotent stem cell-based model for post-implantation human amniotic sac development

    Yue Shao;Kenichiro Taniguchi;Ryan F. Townshend;Toshio Miki

  • Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genes.

    Deborah L. Gumucio;Heidi Heilstedt-Williamson;Todd A. Gray;Susan A. Tarlé

  • Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche.

    Yue Shao;Kenichiro Taniguchi;Katherine Gurdziel;Ryan F. Townshend

  • Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin

    Johann E. Gudjonsson;Jun Ding;Xing Li;Rajan P. Nair

  • The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-κB through its N-terminal fragment

    Jae Jin Chae;Geryl Wood;Katharina Richard;Howard Jaffe

  • High affinity YY1 binding motifs: Identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human β globin cluster

    Stephen R. Yant;Wei Zhu;David Millinoff;Jerry L. Slightom

  • Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning

    Åsa Kolterud;Ann S. Grosse;William J. Zacharias;Katherine D. Walton

  • Prospective identification of a multilineage progenitor in murine stomach epithelium.

    Xiaotan T. Qiao;Joshua W. Ziel;Wendy McKimpson;Blair B. Madison

Frequent Co-Authors

Linda C. Samuelson
Linda C. Samuelson University of Michigan–Ann Arbor
Juanita L. Merchant
Juanita L. Merchant University of Arizona
Morris Goodman
Morris Goodman Wayne State University
Jerry L. Slightom
Jerry L. Slightom AureoGen Biosciences (United States)
Jianping Fu
Jianping Fu University of Michigan–Ann Arbor
Francis S. Collins
Francis S. Collins National Institutes of Health
John Y. Kao
John Y. Kao University of Michigan–Ann Arbor
Daniel L. Kastner
Daniel L. Kastner National Institutes of Health
Andrzej A. Dlugosz
Andrzej A. Dlugosz University of Michigan–Ann Arbor
Miriam H. Meisler
Miriam H. Meisler University of Michigan–Ann Arbor

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