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Microbiology

D-Index
57
Citations
15367
World Ranking
3534
National Ranking
1393

Overview

Ken Cadwell is affiliated with New York University in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology. The scientist's work particularly focuses on infectious diseases, molecular biology, immunology, epidemiology, and genetics.

The main topics of Cadwell's research include:

  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Viral gastroenteritis research and epidemiology
  • Inflammatory Bowel Disease
  • SARS-CoV-2 and COVID-19 research
  • Autophagy in disease and therapy
  • COVID-19 clinical research studies

Ken Cadwell has contributed studies to several publication venues, frequently publishing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • The Journal of Immunology
  • Immunity
  • Cell Host & Microbe

The scientist's recent papers include:

  • "Autophagy in major human diseases," 2021, published in The EMBO Journal
  • "Decoy exosomes provide protection against bacterial toxins," 2020, published in Nature
  • "Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine," 2020, published in Immunity
  • "Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer," 2020, published in Journal of Clinical Investigation
  • "Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia," 2022, published in Nature Communications

Ken Cadwell has collaborated frequently with several co-authors, including:

  • Jordan E. Axelrad
  • P'ng Loke
  • Victor J. Torres
  • Joseph C. Devlin
  • Ying-Han Chen

The cumulative impact of Cadwell's work is evident in the breadth of research topics and the volume of publications in respected journals. Their research contributions involve advanced molecular biology techniques and clinical perspectives, particularly concerning gut health, infectious diseases, and inflammatory conditions.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

    Ken Cadwell;John Y. Liu;Sarah L. Brown;Hiroyuki Miyoshi

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

    Ken Cadwell;Khushbu K. Patel;Nicole S. Maloney;Ta Chiang Liu

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • An enteric virus can replace the beneficial function of commensal bacteria

    Elisabeth Kernbauer;Yi Ding;Ken Cadwell

  • Ubiquitination on Nonlysine Residues by a Viral E3 Ubiquitin Ligase

    Ken Cadwell;Laurent Coscoy

  • Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis

    Ken Cadwell

  • Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens.

    Zijiang Zhao;Blima Fux;Megan Goodwin;Ildiko R. Dunay

  • Helminth infection promotes colonization resistance via type 2 immunity

    Deepshika Ramanan;Rowann Bowcutt;Soo Ching Lee;Mei San Tang

  • The autophagy gene ATG5 plays an essential role in B lymphocyte development.

    Brian C Miller;Zijiang Zhao;Linda M Stephenson;Ken Cadwell

  • Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice

    Alexandra E. Livanos;Thomas U. Greiner;Pajau Vangay;Wimal Pathmasiri

  • Autophagy and Inflammation

    Yu Matsuzawa-Ishimoto;Seungmin Hwang;Ken Cadwell

  • Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

    Khushbu K. Patel;Hiroyuki Miyoshi;Wandy L. Beatty;Richard D. Head

  • Bacterial Sensor Nod2 Prevents Inflammation of the Small Intestine by Restricting the Expansion of the Commensal Bacteroides vulgatus

    Deepshika Ramanan;Mei San Tang;Rowann Bowcutt;P’ng Loke

  • Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.

    Yu Matsuzawa-Ishimoto;Yusuke Shono;Luis E. Gomez;Vanessa M. Hubbard-Lucey

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.

    Ken Cadwell;Khushbu K. Patel;Masaaki Komatsu;Herbert W. Virgin

  • Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

    Unknown

  • Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

    Linda M. Stephenson;Brian C. Miller;Aylwin Ng;Jason Eisenberg

  • Decoy exosomes provide protection against bacterial toxins

    Matthew D. Keller;Krystal L. Ching;Feng-Xia Liang;Avantika Dhabaria

  • Tropism for tuft cells determines immune promotion of norovirus pathogenesis.

    Craig B. Wilen;Sanghyun Lee;Lee-Yang Hsieh;Robert C. Orchard

  • Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine

    Shiyan Yu;Iyshwarya Balasubramanian;Daniel Laubitz;Kevin Tong

Frequent Co-Authors

P'ng Loke
P'ng Loke National Institutes of Health
Noboru Mizushima
Noboru Mizushima University of Tokyo
Victor J. Torres
Victor J. Torres New York University
Sergio Lavandero
Sergio Lavandero University of Chile
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Martin J. Blaser
Martin J. Blaser Rutgers, The State University of New Jersey
Evelina Gatti
Evelina Gatti Aix-Marseille University
Nektarios Tavernarakis
Nektarios Tavernarakis Foundation for Research and Technology Hellas

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