D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 121 Citations 52,092 302 World Ranking 188 National Ranking 123
Medicine D-index 125 Citations 56,817 321 World Ranking 1729 National Ranking 1017

Research.com Recognitions

Awards & Achievements

2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Virus
  • Immune system

His primary scientific interests are in Virology, Autophagy, Cell biology, Immunology and Virus. In his research, Nucleoprotein is intimately related to Antibody, which falls under the overarching field of Virology. His studies deal with areas such as Phagosome, Intracellular parasite and Mycobacterium tuberculosis as well as Autophagy.

The study incorporates disciplines such as Autophagosome and Programmed cell death in addition to Cell biology. His Immunology research incorporates elements of ATG16L1 and Inflammatory bowel disease. His Virus study combines topics in areas such as Heterologous, Gene and Sindbis virus.

His most cited work include:

  • Autophagy in immunity and inflammation (2145 citations)
  • Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 (1557 citations)
  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)

What are the main themes of his work throughout his whole career to date?

Herbert W. Virgin mainly focuses on Virology, Immunology, Cell biology, Immune system and Virus. His work investigates the relationship between Virology and topics such as Antibody that intersect with problems in Vaccination. His study ties his expertise on Cytotoxic T cell together with the subject of Immunology.

His research integrates issues of Autophagy, Receptor, Cell and Programmed cell death in his study of Cell biology. His Autophagy study integrates concerns from other disciplines, such as Intracellular parasite, Vacuole and Innate immune system. His research in Viral replication intersects with topics in Gene and Mutant.

He most often published in these fields:

  • Virology (50.15%)
  • Immunology (28.96%)
  • Cell biology (20.00%)

What were the highlights of his more recent work (between 2017-2021)?

  • Antibody (17.61%)
  • Virology (50.15%)
  • Neutralization (7.76%)

In recent papers he was focusing on the following fields of study:

Herbert W. Virgin focuses on Antibody, Virology, Neutralization, Immune system and Cell biology. His Antibody research includes elements of Glycoprotein, Antigen, Immunity and Vaccination. His work on Neutralizing antibody as part of general Virology study is frequently connected to Severe acute respiratory syndrome coronavirus 2, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

He combines subjects such as Integral membrane protein, Virus, Interferon and Microbiology with his study of Immune system. His work carried out in the field of Cell biology brings together such families of science as Autophagy and Receptor, Innate immune system. His research in Autophagy focuses on subjects like Programmed cell death, which are connected to Neuroscience.

Between 2017 and 2021, his most popular works were:

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody. (585 citations)
  • Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology. (209 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Virus
  • Immune system

The scientist’s investigation covers issues in Antibody, Virology, Monoclonal antibody, Neutralization and Immune system. The various areas that Herbert W. Virgin examines in his Antibody study include Virus and Nucleoprotein. His Virology study focuses on Neutralizing antibody in particular.

While the research belongs to areas of Monoclonal antibody, Herbert W. Virgin spends his time largely on the problem of Polyclonal antibodies, intersecting his research to questions surrounding Recombinant DNA. The concepts of his Immune system study are interwoven with issues in Mutation, Tissue tropism, Virulence and Vaccination. Vaccination is the subject of his research, which falls under Immunology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Autophagy in immunity and inflammation

Beth Levine;Noboru Mizushima;Herbert W. Virgin.
Nature (2011)

3125 Citations

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G Doench;Nicolo Fusi;Meagan Sullender;Mudra Hegde.
Nature Biotechnology (2016)

2581 Citations

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

Dora Pinto;Young Jun Park;Martina Beltramello;Alexandra C. Walls.
Nature (2020)

1807 Citations

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

Ken Cadwell;John Y. Liu;Sarah L. Brown;Hiroyuki Miyoshi.
Nature (2008)

1563 Citations

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

Congcong He;Michael C. Bassik;Michael C. Bassik;Viviana Moresi;Kai Sun;Kai Sun.
Nature (2012)

1142 Citations

Redefining Chronic Viral Infection

Herbert W. Virgin;E. John Wherry;Rafi Ahmed.
Cell (2009)

1015 Citations

Disease-specific alterations in the enteric virome in inflammatory bowel disease.

Jason M. Norman;Scott A. Handley;Megan T. Baldridge;Lindsay Droit.
Cell (2015)

950 Citations

STAT1-Dependent Innate Immunity to a Norwalk-Like Virus

Stephanie M. Karst;Christiane E. Wobus;Margarita Lay;John Davidson.
Science (2003)

949 Citations

Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages

Christiane E. Wobus;Stephanie M. Karst;Larissa B. Thackray;Kyeong Ok Chang.
PLOS Biology (2004)

939 Citations

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

Ken Cadwell;Khushbu K. Patel;Nicole S. Maloney;Ta Chiang Liu.
Cell (2010)

910 Citations

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