World's Best Scientists 2026 revealed!
Herbert W. Virgin

Herbert W. Virgin

Award Badge
Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
141
Citations
84981
World Ranking
155
National Ranking
105

Medicine

D-Index
142
Citations
85729
World Ranking
1548
National Ranking
899

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Herbert W. Virgin is affiliated with Washington University in St. Louis in the United States. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Infectious Diseases, Molecular Biology, Epidemiology, Immunology, and Animal Science and Zoology.

The scientist's work covers a range of important topics such as SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Viral gastroenteritis research and epidemiology, Animal Virus Infections Studies, Autophagy in Disease and Therapy, Virus-based gene therapy research, and vaccines and immunoinformatics approaches.

Frequent co-authors of Herbert W. Virgin include:

  • Davide Corti
  • Amalio Telenti
  • Gyorgy Snell
  • Elisabetta Cameroni
  • David Veesler

The venues in which they have published frequently include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Science
  • Cell
  • Proceedings of the National Academy of Sciences

Recent papers authored or co-authored by Herbert W. Virgin are:

  • Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody, 2020, Nature
  • Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology, 2020, Cell
  • Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift, 2021, Nature
  • Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies, 2021, Nature Medicine
  • N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2, 2021, Cell

Herbert W. Virgin was awarded Fellow of the American Association for the Advancement of Science (AAAS) in 2004.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Autophagy in immunity and inflammation

    Beth Levine;Noboru Mizushima;Herbert W. Virgin

  • Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

    Dora Pinto;Young Jun Park;Martina Beltramello;Alexandra C. Walls

  • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

    Ken Cadwell;John Y. Liu;Sarah L. Brown;Hiroyuki Miyoshi

  • Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.

    Luca Piccoli;Young Jun Park;M. Alejandra Tortorici;M. Alejandra Tortorici;Nadine Czudnochowski

  • Disease-specific alterations in the enteric virome in inflammatory bowel disease.

    Jason M. Norman;Scott A. Handley;Megan T. Baldridge;Lindsay Droit

  • Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

    Congcong He;Michael C. Bassik;Michael C. Bassik;Viviana Moresi;Kai Sun;Kai Sun

  • TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.

    Tyler K. Ulland;Wilbur M. Song;Stanley Ching Cheng Huang;Jason D. Ulrich

  • Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

    Unknown

  • Redefining Chronic Viral Infection

    Herbert W. Virgin;E. John Wherry;Rafi Ahmed

  • STAT1-Dependent Innate Immunity to a Norwalk-Like Virus

    Stephanie M. Karst;Christiane E. Wobus;Margarita Lay;John Davidson

  • Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages

    Christiane E. Wobus;Stephanie M. Karst;Larissa B. Thackray;Kyeong Ok Chang

  • Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

    Ken Cadwell;Khushbu K. Patel;Nicole S. Maloney;Ta Chiang Liu

  • N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.

    Matthew McCallum;Anna De Marco;Florian A. Lempp;M. Alejandra Tortorici;M. Alejandra Tortorici

  • Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

    John W. Schoggins;Donna A. MacDuff;Naoko Imanaka;Maria D. Gainey

  • Complete sequence and genomic analysis of murine gammaherpesvirus 68.

    H W Virgin;P Latreille;P Wamsley;K Hallsworth

  • Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.

    Rita E. Chen;Xianwen Zhang;James Brett Case;Emma S. Winkler

  • Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

    Zsolt Tallóczy;Wenxia Jiang;Herbert W. Virgin;David A. Leib

  • Identification of a candidate therapeutic autophagy-inducing peptide

    Sanae Shoji-Kawata;Rhea Sumpter;Matthew J Leveno;Grant R. Campbell;Grant R. Campbell

  • Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

    Jennifer Martinez;R. K.Subbarao Malireddi;Qun Lu;Larissa Dias Cunha

  • Murine Norovirus: a Model System To Study Norovirus Biology and Pathogenesis

    Christiane E. Wobus;Larissa B. Thackray;Herbert W. Virgin

  • Herpesvirus latency confers symbiotic protection from bacterial infection

    Erik S. Barton;Douglas W. White;Jason S. Cathelyn;Kelly A. Brett-McClellan

  • Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

    Melis N. Anahtar;Melis N. Anahtar;Elizabeth H. Byrne;Kathleen E. Doherty;Brittany A. Bowman

  • The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

    Robert O. Watson;Samantha L. Bell;Donna A. MacDuff;Jacqueline M. Kimmey

  • Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.

    Dami A. Collier;Dami A. Collier;Anna De Marco;Isabella A. T. M. Ferreira;Bo Meng

  • Autophagy Links Inflammasomes to Atherosclerotic Progression

    Babak Razani;Chu Feng;Trey Coleman;Roy Emanuel

  • Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.

    Emma C. Thomson;Emma C. Thomson;Laura E. Rosen;James G. Shepherd;Roberto Spreafico

Frequent Co-Authors

Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Davide Corti
Davide Corti Vir Biotechnology (Switzerland)
Samuel H. Speck
Samuel H. Speck Emory University
Michael S. Diamond
Michael S. Diamond Washington University in St. Louis
David Wang
David Wang Washington University in St. Louis
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Larissa B. Thackray
Larissa B. Thackray Washington University in St. Louis
Craig B. Wilen
Craig B. Wilen Yale University
M. Alejandra Tortorici
M. Alejandra Tortorici University of Washington
Christiane E. Wobus
Christiane E. Wobus University of Michigan–Ann Arbor

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