World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
58
Citations
18097
World Ranking
3365
National Ranking
1325

Overview

Craig B. Wilen is affiliated with Yale University in the United States and has contributed extensively to research in medicine, with a focus on infectious diseases. Their work covers several subfields, including immunology, molecular biology, animal science and zoology, and genetics.

The scientist's research primarily revolves around SARS-CoV-2 and COVID-19, encompassing both virological and clinical aspects of the pandemic. They have also worked on viral gastroenteritis, animal virus infections, interferon and immune responses, virus-based gene therapy, and the long-term effects of COVID-19.

Craig B. Wilen's frequent co-authors include:

  • Mia Madel Alfajaro
  • Renata B. Filler
  • Akiko Iwasaki
  • Jin Wei
  • Madison S. Strine

Their publications are often featured in prominent scientific venues, with a concentration in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Virology
  • PLoS Pathogens
  • The Journal of Experimental Medicine

Among recent papers, several have gained notable citations:

  • Neuroinvasion of SARS-CoV-2 in human and mouse brain, 2020, The Journal of Experimental Medicine
  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection, 2020, Cell
  • Inflammasome activation in infected macrophages drives COVID-19 pathology, 2022, Nature
  • Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling, 2020, The Journal of Experimental Medicine
  • Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms, 2021, Molecular Cell

Best Publications

  • Neuroinvasion of SARS-CoV-2 in human and mouse brain.

    Eric Song;Ce Zhang;Benjamin Israelow;Alice Lu-Culligan

  • HIV: Cell Binding and Entry

    Craig B. Wilen;John Christian Tilton;Robert W. Doms

  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.

    Jin Wei;Mia Madel Alfajaro;Peter C. DeWeirdt;Ruth E. Hanna

  • Phenotypic properties of transmitted founder HIV-1

    Nicholas F. Parrish;Feng Gao;Hui Li;Elena E. Giorgi

  • Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

    Cynthia L. Monaco;David B. Gootenberg;Guoyan Zhao;Scott A. Handley

  • De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report

    Unknown

  • Mouse Model of SARS-CoV-2 Reveals Inflammatory Role of Type I Interferon Signaling

    Benjamin Israelow;Eric Song;Tianyang Mao;Peiwen Lu

  • Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.

    Jonathan R. Brestoff;Craig B. Wilen;John R. Moley;Yongjia Li

  • Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms.

    Nicholas C. Huston;Han Wan;Madison S. Strine;Rafael de Cesaris Araujo Tavares

  • Discovery of a proteinaceous cellular receptor for a norovirus

    Robert C. Orchard;Craig B. Wilen;John G. Doench;Megan T. Baldridge

  • Molecular mechanisms of HIV entry.

    Craig B. Wilen;John C. Tilton;Robert W. Doms

  • Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.

    Neal G Ravindra;Mia Madel Alfajaro;Victor Gasque;Nicholas C Huston

  • Tropism for tuft cells determines immune promotion of norovirus pathogenesis.

    Craig B. Wilen;Sanghyun Lee;Lee-Yang Hsieh;Robert C. Orchard

  • Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.

    Irfan Ullah;Jérémie Prévost;Mark S. Ladinsky;Helen Stone

  • Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.

    Jack Chun-Chieh Hsu;Maudry Laurent-Rolle;Joanna B. Pawlak;Craig B. Wilen

  • Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.

    Ryan A. Flynn;Julia A. Belk;Yanyan Qi;Yuki Yasumoto

  • Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection

    Chuka A. Didigu;Craig B. Wilen;Jianbin Wang;Jennifer Duong

  • Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7

    Nicholas F. Parrish;Craig B. Wilen;Lauren B. Banks;Shilpa S. Iyer

  • Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.

    Craig B. Wilen;Jianbin Wang;John C. Tilton;Jeffrey C. Miller

  • Phenotypic and Immunologic Comparison of Clade B Transmitted/Founder and Chronic HIV-1 Envelope Glycoproteins

    Craig B. Wilen;Nicholas F. Parrish;Jennifer M. Pfaff;Julie M. Decker

  • Neuroinvasion of SARS-CoV-2 in human and mouse brain

    Eric Song;Ce Zhang;Benjamin Israelow;Alice Lu-Culligan

  • A Maraviroc-Resistant HIV-1 with Narrow Cross-Resistance to Other CCR5 Antagonists Depends on both N-Terminal and Extracellular Loop Domains of Drug-Bound CCR5

    John C. Tilton;Craig B. Wilen;Chukwuka A. Didigu;Rohini Sinha

Frequent Co-Authors

Akiko Iwasaki
Akiko Iwasaki Yale University
Robert W. Doms
Robert W. Doms Children's Hospital of Philadelphia
Anna Marie Pyle
Anna Marie Pyle Yale University
Aaron M. Ring
Aaron M. Ring Yale University
Tamas L. Horvath
Tamas L. Horvath Yale University
Albert I. Ko
Albert I. Ko Yale University
John G. Doench
John G. Doench Broad Institute
Charles S. Dela Cruz
Charles S. Dela Cruz Yale University
Chantal B. F. Vogels
Chantal B. F. Vogels Yale University

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