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Molecular Biology

D-Index
62
Citations
30436
World Ranking
1827
National Ranking
914

Overview

Duojia Pan is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on Cell Biology and Molecular Biology as subfields. Their work also extends into Immunology and Allergy, Oncology, and Physiology.

The major topics covered in their research include:

  • Hippo pathway signaling and YAP/TAZ
  • Cellular Mechanics and Interactions
  • Wnt/β-catenin signaling in development and cancer
  • Cancer-related gene regulation
  • Epigenetics and DNA Methylation
  • Cell Adhesion Molecules Research
  • Microtubule and mitosis dynamics

Several recent papers highlight their ongoing contributions to the field:

  • "The Hippo Pathway in Liver Homeostasis and Pathophysiology," 2020, Annual Review of Pathology Mechanisms of Disease
  • "Control of stem cell renewal and fate by YAP and TAZ," 2023, Nature Reviews Molecular Cell Biology
  • "Multiphase coalescence mediates Hippo pathway activation," 2022, Cell
  • "A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth," 2022, Nature Metabolism
  • "YAP/TAZ drives cell proliferation and tumour growth via a polyamine-eIF5A hypusination-LSD1 axis," 2022, Nature Cell Biology

Duojia Pan has published multiple articles in reputable venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genes & Development
  • eLife
  • Nature Cell Biology
  • Annual Review of Pathology Mechanisms of Disease

Frequent coauthors contributing to joint research efforts include:

  • Yonggang Zheng
  • Jonathan E Phillips
  • Jordan H. Driskill
  • Elizabeth H. Chen
  • Ruihui Zhang

Best Publications

  • Elucidation of a universal size-control mechanism in Drosophila and mammals.

    Jixin Dong;Georg Feldmann;Jianbin Huang;Shian Wu

  • The Hippo Signaling Pathway in Development and Cancer

    Duojia Pan

  • The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

    Jianbin Huang;Shian Wu;Jose Barrera;Krista Matthews

  • Genetic and pharmacological disruption of the TEAD–YAP complex suppresses the oncogenic activity of YAP

    Yi Liu-Chittenden;Bo Huang;Joong Sup Shim;Qian Chen

  • hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts

    Shian Wu;Jianbin Huang;Jixin Dong;Duojia Pan

  • A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1

    Jeffrey S. Mumm;Eric H. Schroeter;Meera T. Saxena;Adam Griesemer

  • Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.

    Yong Zhang;Yong Zhang;Xinsheng Gao;Leslie J. Saucedo;Binggen Ru

  • Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.

    Xinsheng Gao;Yong Zhang;Peter Arrazola;Okio Hino

  • The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

    Nailing Zhang;Haibo Bai;Karen K. David;Jixin Dong

  • Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

    Claudio Alarcón;Alexia Ileana Zaromytidou;Qiaoran Xi;Sheng Gao

  • Hippo signaling in organ size control

    Duojia Pan

  • The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway

    Shian Wu;Yi Liu;Yonggang Zheng;Jixin Dong

  • Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis

    Duojia Pan;Gerald M Rubin

  • The Hippo Signaling Pathway in Development and Disease.

    Yonggang Zheng;Duojia Pan

  • Expression of Yes-associated protein in common solid tumors

    Angela A. Steinhardt;Mariana F. Gayyed;Mariana F. Gayyed;Alison P. Klein;Jixin Dong

  • TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth.

    Xinsheng Gao;Duojia Pan

  • Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded

    Jianzhong Yu;Yonggang Zheng;Jixin Dong;Stephen Klusza

  • The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

    Jing Cai;Nailing Zhang;Yonggang Zheng;Roeland F. de Wilde

  • Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

    Feng Yin;Jianzhong Yu;Yonggang Zheng;Qian Chen

  • KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

    Jenny Rooke;Duojia Pan;Tian Xu;Gerald M. Rubin

Frequent Co-Authors

Robert A. Anders
Robert A. Anders Johns Hopkins University School of Medicine
Anirban Maitra
Anirban Maitra The University of Texas MD Anderson Cancer Center
Gianfranco Alpini
Gianfranco Alpini Indiana University
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute
Junichi Sadoshima
Junichi Sadoshima Rutgers, The State University of New Jersey
Saraswati Sukumar
Saraswati Sukumar Johns Hopkins University School of Medicine
Jason B. Fleming
Jason B. Fleming The University of Texas MD Anderson Cancer Center
Haoqiang Ying
Haoqiang Ying The University of Texas MD Anderson Cancer Center
Giulio Draetta
Giulio Draetta The University of Texas MD Anderson Cancer Center
Steven J.M. Jones
Steven J.M. Jones University of British Columbia

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