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Medicine

D-Index
89
Citations
35763
World Ranking
12526
National Ranking
6412

Overview

Jason B. Fleming is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on fields related to medicine and biochemistry, genetics, and molecular biology, with significant contributions to oncology, molecular biology, cancer research, surgery, and pulmonary and respiratory medicine.

Their main topics of study include pancreatic and hepatic oncology research, cancer genomics and diagnostics, cholangiocarcinoma and gallbladder cancer studies, pancreatitis pathology and treatment, genetic factors in colorectal cancer, economic and financial impacts of cancer, and colorectal cancer treatments and studies.

Key recent publications highlight their continued work in pancreatic cancer and related molecular mechanisms. These include:

  • Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis (2021, Cancer Discovery)
  • DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis (2021, JCI Insight)
  • IGFBP2 promotes tumor progression by inducing alternative polarization of macrophages in pancreatic ductal adenocarcinoma through the STAT3 pathway (2020, Cancer Letters)
  • PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma (2021, Nature Communications)
  • APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis (2021, Nature Cancer)

Jason B. Fleming frequently publishes in the following venues:

  • Journal of Clinical Oncology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • HPB

Their collaboration network includes repeated coauthorships with Jason W. Denbo, Mokenge P. Malafa, Pamela J. Hodul, Jennifer B. Permuth, and Daniel A. Anaya, reflecting sustained research partnerships in their areas of interest.

Best Publications

  • One Hundred Years After “Carcinoid”: Epidemiology of and Prognostic Factors for Neuroendocrine Tumors in 35,825 Cases in the United States

    James C. Yao;Manal Hassan;Alexandria T. Phan;Cecile Dagohoy

  • Glutamine supports pancreatic cancer growth through a Kras-regulated metabolic pathway

    Jaekyoung Son;Costas A. Lyssiotis;Costas A. Lyssiotis;Haoqiang Ying;Xiaoxu Wang

  • Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

    Leore T. Geller;Michal Barzily-Rokni;Tal Danino;Oliver H. Jonas;Oliver H. Jonas

  • Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

    Andrea Viale;Piergiorgio Pettazzoni;Costas A. Lyssiotis;Haoqiang Ying

  • Borderline resectable pancreatic cancer: the importance of this emerging stage of disease.

    Matthew H.G. Katz;Peter W.T. Pisters;Douglas B. Evans;Charlotte C. Sun

  • MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer.

    Surendra K. Shukla;Vinee Purohit;Kamiya Mehla;Venugopal Gunda

  • Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma

    Matthew Harold Katz;Matthew Harold Katz;Huamin Wang;Jason B Fleming;Charlotte C Sun

  • KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

    Jianhua Ling;Ya'an Kang;Ruiying Zhao;Qianghua Xia

  • Response of borderline resectable pancreatic cancer to neoadjuvant therapy is not reflected by radiographic indicators

    Matthew Harold Katz;Jason B Fleming;Priya R Bhosale;Gauri R Varadhachary

  • Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice

    Michael P Kim;Douglas B Evans;Huamin Wang;James L Abbruzzese

  • Postoperative complications reduce adjuvant chemotherapy use in resectable pancreatic cancer

    Ryan P. Merkow;Karl Y. Bilimoria;James S. Tomlinson;Jennifer L. Paruch;Jennifer L. Paruch

  • Phase II Trial of Cetuximab, Gemcitabine, and Oxaliplatin Followed by Chemoradiation With Cetuximab for Locally Advanced (T4) Pancreatic Adenocarcinoma: Correlation of Smad4(Dpc4) Immunostaining With Pattern of Disease Progression

    Christopher H. Crane;Gauri R. Varadhachary;John S. Yordy;Gregg A. Staerkel

  • Comparison of video trainer and virtual reality training systems on acquisition of laparoscopic skills.

    Elizabeth Costa Hamilton;Daniel J Scott;J. B. Fleming;Robert V Rege

  • LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

    Davide Melisi;Satoshi Ishiyama;Guido M. Sclabas;Jason B. Fleming

  • Emergency Surgery for Colon Carcinoma

    Lane Smothers;Linda Hynan;Jason Fleming;Richard Turnage

  • Sentinel Lymph Node Biopsy Is Accurate After Neoadjuvant Chemotherapy for Breast Cancer

    Tara M. Breslin;Lisa Cohen;Aysegul A Sahin;Jason B. Fleming

  • Focal Radiation Therapy Dose Escalation Improves Overall Survival in Locally Advanced Pancreatic Cancer Patients Receiving Induction Chemotherapy and Consolidative Chemoradiation

    Sunil Krishnan;Awalpreet S. Chadha;Yelin Suh;Hsiang Chun Chen

  • Monitoring Response to Anticancer Therapy by Targeting Microbubbles to Tumor Vasculature

    Grzegorz Korpanty;Juliet G. Carbon;Paul A. Grayburn;Jason B. Fleming

  • Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference.

    Noelle Sevilir Williams;Richard B. Gaynor;Shane Scoggin;Udit Verma

  • ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma

    Michael P. Kim;Jason B. Fleming;Huamin Wang;James L Abbruzzese

Frequent Co-Authors

Jeffrey E. Lee
Jeffrey E. Lee The University of Texas MD Anderson Cancer Center
Huamin Wang
Huamin Wang The University of Texas MD Anderson Cancer Center
Robert A. Wolff
Robert A. Wolff The University of Texas MD Anderson Cancer Center
Jean Nicolas Vauthey
Jean Nicolas Vauthey The University of Texas MD Anderson Cancer Center
Christopher H. Crane
Christopher H. Crane Memorial Sloan Kettering Cancer Center
James L. Abbruzzese
James L. Abbruzzese Duke University
Douglas B. Evans
Douglas B. Evans Medical College of Wisconsin
Peter W.T. Pisters
Peter W.T. Pisters The University of Texas MD Anderson Cancer Center
Anirban Maitra
Anirban Maitra The University of Texas MD Anderson Cancer Center
Asif Rashid
Asif Rashid The University of Texas MD Anderson Cancer Center

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