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Medicine

D-Index
92
Citations
32558
World Ranking
11271
National Ranking
5786

Overview

Matthew H. Kulke is affiliated with Boston Medical Center in the United States. Their research primarily focuses on medicine, with a significant concentration in oncology. Within this field, they have contributed extensively to subfields such as oncology, epidemiology, neurology, pulmonary and respiratory medicine, and molecular biology.

Their research topics cover a range of cancer-related studies, including neuroendocrine tumor research advances, lung cancer research studies, neuroblastoma research and treatments, pancreatic and hepatic oncology research, lung cancer treatments and mutations, colorectal cancer treatments and studies, and gestational trophoblastic disease studies.

Kulke has authored several recent publications, including:

  • PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer (2023), published in Molecular Cancer
  • Randomized Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine Tumors (ECOG-ACRIN E2211) (2022), published in Journal of Clinical Oncology
  • Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with 177Lu-Dotatate: an analysis of the NETTER-1 study (2020), published in European Journal of Nuclear Medicine and Molecular Imaging
  • Phase 3 Trial of Cabozantinib to Treat Advanced Neuroendocrine Tumors (2024), published in New England Journal of Medicine
  • Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions (2021), published in Clinical Cancer Research

Frequent collaborators in their research include:

  • Jonathan Strosberg
  • Jennifer A. Chan
  • Lauren K. Brais
  • James C. Yao
  • Kimberly Perez

The main venues where their work is published include:

  • Journal of Clinical Oncology
  • Pancreas
  • The Oncologist
  • UNC Libraries
  • Clinical Cancer Research

Best Publications

  • Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors

    Jonathan Strosberg;G. El-Haddad;Edward Wolin;A. Hendifar

  • Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study

    James C. Yao;Nicola Fazio;Simron Singh;Roberto Buzzoni

  • Daily Oral Everolimus Activity in Patients with Metastatic Pancreatic Neuroendocrine Tumors after Failure of Cytotoxic Chemotherapy: A Phase II Trial

    James C. Yao;Catherine Lombard-Bohas;Eric Baudin;Larry K. Kvols

  • Activity of Sunitinib in Patients With Advanced Neuroendocrine Tumors

    Matthew H. Kulke;Heinz Josef Lenz;Neal J. Meropol;James Posey

  • NANETS treatment guidelines: well-differentiated neuroendocrine tumors of the stomach and pancreas.

    Matthew H. Kulke;Lowell B. Anthony;David L. Bushnell;Wouter W. de Herder

  • Consensus guidelines for the management and treatment of neuroendocrine tumors.

    Pamela L. Kunz;Diane Reidy-Lagunes;Lowell B. Anthony;Erin M. Bertino

  • Phase II Study of Temozolomide and Thalidomide in Patients With Metastatic Neuroendocrine Tumors

    Matthew H. Kulke;Keith Stuart;Peter C. Enzinger;David P. Ryan

  • Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing.

    Jin Li;Lilin Wang;Harvey Mamon;Matthew H Kulke

  • Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.

    Matthew B. Yurgelun;Matthew H. Kulke;Charles S. Fuchs;Brian A. Allen

  • Pathology reporting of neuroendocrine tumors: application of the Delphic consensus process to the development of a minimum pathology data set

    David S. Klimstra;Irvin R. Modlin;N. Volkan Adsay;Runjan Chetty

  • O6-Methylguanine DNA Methyltransferase Deficiency and Response to Temozolomide-Based Therapy in Patients with Neuroendocrine Tumors

    Matthew H. Kulke;Jason L. Hornick;Christine Frauenhoffer;Susanne Hooshmand

  • Passive Stiffness Changes Caused by Upregulation of Compliant Titin Isoforms in Human Dilated Cardiomyopathy Hearts

    I. Makarenko;C.A. Opitz;M.C. Leake;C. Neagoe

  • Neuroendocrine tumors, version 1.2015

    Matthew H. Kulke;Manisha H. Shah;Al B. Benson;Emily Bergsland

  • The NANETS consensus guidelines for the diagnosis and management of poorly differentiated (High-Grade) extrapulmonary neuroendocrine carcinomas

    Jonathan R. Strosberg;Domenico Coppola;David S. Klimstra;Alexandria T. Phan

  • Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer.

    J Souglakos;J Philips;R Wang;S Marwah

  • NCCN Clinical Practice Guidelines in Oncology: neuroendocrine tumors.

    Clark Oh;Benson Ab rd;Berlin Jd;Choti Ma

  • Future Directions in the Treatment of Neuroendocrine Tumors: Consensus Report of the National Cancer Institute Neuroendocrine Tumor Clinical Trials Planning Meeting

    Matthew H. Kulke;Lillian L. Siu;Joel E. Tepper;George Fisher

  • Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

    Brian M. Wolpin;Cosmeri Rizzato;Peter Kraft;Charles Kooperberg

  • Somatic mutation of CDKN1B in small intestine neuroendocrine tumors

    Joshua M Francis;Joshua M Francis;Adam Kiezun;Alex H Ramos;Alex H Ramos;Stefano Serra

  • Health-Related Quality of Life in Patients With Progressive Midgut Neuroendocrine Tumors Treated With 177Lu-Dotatate in the Phase III NETTER-1 Trial.

    Jonathan Strosberg;Edward Wolin;Beth Chasen;Matthew Kulke

Frequent Co-Authors

Kjell Öberg
Kjell Öberg Uppsala University
James C. Yao
James C. Yao The University of Texas MD Anderson Cancer Center
Jennifer A. Chan
Jennifer A. Chan University of Calgary
David C. Christiani
David C. Christiani Harvard University
Jeffrey A. Meyerhardt
Jeffrey A. Meyerhardt Harvard University
Geoffrey Liu
Geoffrey Liu Princess Margaret Cancer Centre
David P. Ryan
David P. Ryan Harvard University
Juan W. Valle
Juan W. Valle University of Manchester
Jeffrey W. Clark
Jeffrey W. Clark Harvard University

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