World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10826
World Ranking
13922
National Ranking
5884

Overview

Ross L. Cagan is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans multiple aspects of molecular biology and medical science, with a particular focus on cancer and related biological pathways. They have contributed extensively to the fields of biochemistry, genetics, and molecular biology, with notable work in subfields such as molecular biology, cell biology, cancer research, oncology, and immunology.

Key topics within Cagan's research include cancer genomics and diagnostics, ubiquitin and proteasome pathways, genetics, bioinformatics, and biomedical research. Additional areas of study encompass microtubule and mitosis dynamics, protein tyrosine phosphatases, Hippo pathway signaling and YAP/TAZ, and PI3K/AKT/mTOR signaling in cancer.

Recent publications from Cagan include:

  • Drosophila RASopathy models identify disease subtype differences and biomarkers of drug efficacy, 2021, iScience
  • A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma, 2021, iScience
  • Cell competition and cancer from Drosophila to mammals, 2024, Oncogenesis
  • Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge, 2021, PLoS Computational Biology
  • Existing and Developing Preclinical Models for Neurofibromatosis Type 1−Related Cutaneous Neurofibromas, 2023, Journal of Investigative Dermatology

Frequent co-authors collaborating with Cagan include Sindhura Gopinath, Bojie Cong, Tirtha K. Das, Chana Hecht, and Verena Staedtke.

Their work is often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Investigative Dermatology, iScience, Disease Models & Mechanisms, and Cancer Research.

Best Publications

  • A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila

    Laura Palanker Musselman;Jill L. Fink;Kirk Narzinski;Prasanna Venkatesh Ramachandran

  • Notch is required for successive cell decisions in the developing Drosophila retina.

    Ross L. Cagan;Donald F. Ready

  • The emergence of order in the Drosophila pupal retina.

    Ross L. Cagan;Donald F. Ready

  • Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor

    H. Krämer;R.L. Cagan;S.L. Zipursky

  • Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

    Arvin C. Dar;Tirtha K. Das;Kevan M. Shokat;Ross L. Cagan

  • The San Francisco Declaration on Research Assessment.

    Ross Cagan

  • Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter

    Julia B. Cordero;Juan P. Macagno;Rhoda K. Stefanatos;Karen E. Strathdee

  • A Drosophila Model of High Sugar Diet-Induced Cardiomyopathy

    Jianbo Na;Laura Palanker Musselman;Jay Pendse;Thomas J. Baranski

  • Local induction of patterning and programmed cell death in the developing Drosophila retina

    David T. Miller;Ross L. Cagan

  • The bride of sevenless and sevenless interaction: Internalization of a transmembrane ligand

    Ross L. Cagan;Helmut Krämer;Anne C. Hart;S.Lawrence Zipursky

  • Induction in the developing compound eye of Drosophila: Multiple mechanisms restrict R7 induction to a single retinal precursor cell

    David L. Van Vactor;Ross L. Cagan;Helmut Krämer;S.Lawrence Zipursky

  • Preferential Adhesion Mediated by Hibris and Roughest Regulates Morphogenesis and Patterning in the Drosophila Eye

    Sujin Bao;Ross Cagan

  • Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis.

    Marcos Vidal;David E. Larson;Ross L. Cagan

  • DNA microarrays and beyond: completing the journey from tissue to cell

    Jason C. Mills;Kevin A. Roth;Ross L. Cagan;Jeffrey I. Gordon

  • Atonal, rough and the resolution of proneural clusters in the developing Drosophila retina

    M.E. Dokucu;S.L. Zipursky;R.L. Cagan

  • Drosophila models for cancer research

    Marcos Vidal;Ross L Cagan

  • ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma.

    Marcos Vidal;Samuel Wells;Anderson Ryan;Ross Cagan

  • Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.

    Rebecca Hays;Laura Wickline;Ross Cagan

  • Drosophila cancer models.

    Vivek A. Rudrapatna;Ross L. Cagan;Tirtha K. Das

  • Modeling Human Cancers in Drosophila

    M Sonoshita;R L Cagan

Frequent Co-Authors

Marshall R. Posner
Marshall R. Posner Icahn School of Medicine at Mount Sinai
David E. Larson
David E. Larson Washington University in St. Louis
Owen J. Sansom
Owen J. Sansom University of Glasgow
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai
S. Lawrence Zipursky
S. Lawrence Zipursky University of California, Los Angeles
Ming-Ming Zhou
Ming-Ming Zhou Icahn School of Medicine at Mount Sinai
Hualiang Jiang
Hualiang Jiang Chinese Academy of Sciences
Leonard I. Zon
Leonard I. Zon Harvard University
Shu-Hsia Chen
Shu-Hsia Chen Icahn School of Medicine at Mount Sinai
Ruben Abagyan
Ruben Abagyan University of California, San Diego

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Ross L. Cagan

Trending Scientists