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Immunology

D-Index
51
Citations
15095
World Ranking
4112
National Ranking
1873

Overview

Shu-Hsia Chen is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology, with a focus on oncology and immunology.

The scientist's work includes significant contributions to the following main topics:

  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Cancer Cells and Metastasis
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Cancer Research and Treatments

In terms of subfields, their publications concentrate on:

  • Oncology
  • Immunology
  • Molecular Biology
  • Cancer Research
  • Genetics

Chen's research has been published frequently in several venues, including:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Advanced Science
  • Cancer Research Communications

Some of their recent papers include:

  • "Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection," 2021, Angewandte Chemie International Edition
  • "A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer," 2021, Science Translational Medicine
  • "Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1," 2020, International Journal of Radiation Oncology*Biology*Physics
  • "Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy," 2020, Science Advances
  • "Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal," 2023, Cell Stem Cell

Their collaborations involve frequent co-authorship with several researchers, including:

  • Yitian Xu
  • Ping-Ying Pan
  • Licheng Zhang
  • Junjun Zheng
  • Nourhan Abdelfattah

Best Publications

  • Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

    Vincenzo Bronte;Sven Brandau;Shu Hsia Chen;Mario P. Colombo

  • Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

    Bo Huang;Ping Ying Pan;Qingsheng Li;Alice I. Sato

  • The terminology issue for myeloid-derived suppressor cells.

    Dmitry I. Gabrilovich;Vincenzo Bronte;Shu Hsia Chen;Mario P. Colombo

  • The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies.

    Junko Ozao-Choy;Ge Ma;Johnny Kao;George X. Wang

  • Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer.

    Ping Ying Pan;Ge Ma;Kaare J. Weber;Junko Ozao-Choy

  • Gr-1+ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation

    Sergei A. Kusmartsev;Yu Li;Shu-Hsia Chen

  • Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function

    Ping Ying Pan;George X. Wang;Bingjiao Yin;Junko Ozao

  • Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice.

    Catherine Martel;Wenjun Li;Brian Fulp;Andrew M. Platt

  • Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

    Yongpeng Gu;Jianfei Yang;Xinshou Ouyang;Weicheng Liu

  • Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

    Junke Zheng;Junke Zheng;Masato Umikawa;Masato Umikawa;Changhao Cui;Jiyuan Li

  • Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model.

    Bert W. O'Malley;Shu Hsia Chen;Mary R. Schwartz;Savio L C Woo

  • Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity

    Hui-Ming Chen;William van der Touw;Yuan Shuo Wang;Kyeongah Kang

  • Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice

    Mercedes Rodriguez Garcia;Levi Ledgerwood;Yu Yang;Jiangnan Xu

  • Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells

    Ge Ma;Ping Ying Pan;Samuel Eisenstein;Celia M. Divino

  • Myeloid-Derived Suppressor Cells Prevent Type 1 Diabetes in Murine Models

    Bingjiao Yin;Ge Ma;Chun Yu Yen;Chun Yu Yen;Zuping Zhou

  • DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance.

    Patricia Conde;Mercedes Rodriguez;William van der Touw;Ana Jimenez

  • Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells.

    Zuping Zhou;Deborah L. French;G. E. Ma;Samuel Eisenstein

  • Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release.

    Padmini Jayaraman;Falguni Parikh;Esther Lopez-Rivera;Yared Hailemichael

  • Targeting immune suppressing myeloid-derived suppressor cells in oncology

    Johnny Kao;Eric C. Ko;Samuel Eisenstein;Andrew G. Sikora

  • Adenovirus‐mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer

    Simon J. Hall;Steven E. Mutchnik;Shu Hsia Chen;Savio L C Woo

  • Combination Gene Therapy for Oral Cancer in a Murine Model

    Bert W. O'Malley;Keary A. Cope;Shu Hsia Chen;Daqing Li

  • Role of immature myeloid Gr-1+ cells in the development of antitumor immunity.

    Qingsheng Li;Ping-Ying Pan;Peidi Gu;Dongping Xu

  • Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: Long-term remission of liver metastases in a mouse model

    Olivier Martinet;Vanadyia Ermekova;Jian Q. Qiao;Bernhard Sauter

Frequent Co-Authors

Savio L. C. Woo
Savio L. C. Woo Icahn School of Medicine at Mount Sinai
Myron Schwartz
Myron Schwartz Icahn School of Medicine at Mount Sinai
Swan N. Thung
Swan N. Thung Icahn School of Medicine at Mount Sinai
Jordi Ochando
Jordi Ochando Icahn School of Medicine at Mount Sinai
Gwendalyn J. Randolph
Gwendalyn J. Randolph Washington University in St. Louis
Richard G. Stock
Richard G. Stock Icahn School of Medicine at Mount Sinai
Jonathan S. Bromberg
Jonathan S. Bromberg University of Maryland, Baltimore
Ming-Ming Zhou
Ming-Ming Zhou Icahn School of Medicine at Mount Sinai
Huabao Xiong
Huabao Xiong Icahn School of Medicine at Mount Sinai
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai

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