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Anthony O. Gramolini

Anthony O. Gramolini

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
9794
World Ranking
17580
National Ranking
611

Overview

Anthony O. Gramolini is affiliated with the University of Toronto in Canada. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a strong focus on cardiology and cardiovascular medicine.

The scientist's work covers several specialized subfields, including cardiology and cardiovascular medicine, molecular biology, surgery, biomedical engineering, and biomaterials. Gramolini's research topics include cardiomyopathy and myosin studies, cardiac fibrosis and remodeling, cardiac electrophysiology and arrhythmias, tissue engineering and regenerative medicine, cardiovascular effects of exercise, cardiovascular function and risk factors, and electrospun nanofibers in biomedical applications.

Gramolini has contributed to numerous recent papers, demonstrating active engagement with current scientific challenges in cardiac health. Some of these publications include:

  • "Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality" (2020, ESC Heart Failure)
  • "Machine Learning Compared With Conventional Statistical Models for Predicting Myocardial Infarction Readmission and Mortality: A Systematic Review" (2021, Canadian Journal of Cardiology)
  • "Insulin-like growth factor-binding protein-7 (IGFBP7) links senescence to heart failure" (2022, Nature Cardiovascular Research)
  • "REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects" (2020, Nature Communications)
  • "An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy" (2021, Journal of Molecular and Cellular Cardiology)

The venues where Gramolini frequently publishes include:

  • Journal of Molecular and Cellular Cardiology Plus
  • Circulation Research
  • Journal of Molecular and Cellular Cardiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation

Frequent collaborators in their scientific work comprise:

  • Uroš Kuzmanov
  • Allen C. T. Teng
  • Cristine J. Reitz
  • Meghan J. McFadden
  • Filio Billia

Gramolini's academic production is grounded in extensive expertise within these areas, supported by a well-established network of co-authors and publication venues. Their publication record reflects a sustained effort in exploring the molecular and clinical aspects of cardiovascular disease, particularly focused on cardiac function, remodeling, and novel methods such as machine learning applied to cardiac readmission and mortality prediction.

Best Publications

  • Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

    Peter J. Mohler;Jean-Jacques Schott;Anthony O. Gramolini;Keith W. Dilly

  • SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells

    Nicole C Dubois;April M Craft;Parveen Sharma;David A Elliott

  • Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling.

    Thomas Kislinger;Brian Cox;Anitha Kannan;Clement Chung

  • Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

    Kobra Haghighi;Fotis Kolokathis;Luke Pater;Roy A. Lynch

  • A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy

    Kobra Haghighi;Fotis Kolokathis;Anthony O. Gramolini;Jason R. Waggoner

  • Self-renewing resident arterial macrophages arise from embryonic CX3CR1 + precursors and circulating monocytes immediately after birth

    Sherine Ensan;Angela Li;Rickvinder Besla;Norbert Degousee

  • Multidimensional protein identification technology (MudPIT): Technical overview of a profiling method optimized for the comprehensive proteomic investigation of normal and diseased heart tissue

    Thomas Kislinger;Anthony O. Gramolini;David H. MacLennan;Andrew Emili

  • Proteome Dynamics during C2C12 Myoblast Differentiation

    Thomas Kislinger;Anthony O. Gramolini;Yan Pan;Khaled Rahman

  • Cardiovascular proteomics: tools to develop novel biomarkers and potential applications.

    Sara Arab;Anthony O. Gramolini;Anthony O. Gramolini;Peipei Ping;Thomas Kislinger

  • The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

    Peter J. Mohler;Anthony O. Gramolini;Vann Bennett

  • Induction of utrophin gene expression by heregulin in skeletal muscle cells: Role of the N-box motif and GA binding protein

    Anthony O. Gramolini;Lindsay M. Angus;Laurent Schaeffer;Edward A. Burton

  • Cell-Surface Proteomics Identifies Lineage-Specific Markers of Embryo-Derived Stem Cells

    Peter J. Rugg-Gunn;Brian J. Cox;Fredrik Lanner;Parveen Sharma

  • Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice

    Michio Asahi;Kinya Otsu;Hiroyuki Nakayama;Shungo Hikoso

  • Genes, proteins and complexes: the multifaceted nature of FHL family proteins in diverse tissues.

    Thiruchelvi Shathasivam;Thomas Kislinger;Thomas Kislinger;Anthony O. Gramolini

  • Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction

    Maria Giovanna Trivieri;Gavin Y. Oudit;Rajan Sah;Benoit Gilles Kerfant

  • Comparative Proteomics Profiling of a Phospholamban Mutant Mouse Model of Dilated Cardiomyopathy Reveals Progressive Intracellular Stress Responses

    Anthony O. Gramolini;Thomas Kislinger;Rasoul Alikhani-Koopaei;Vincent Fong

  • Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer

    Yunee Kim;Jouhyun Jeon;Salvador Mejia;Cindy Q Yao;Cindy Q Yao

  • Local Transcriptional Control of Utrophin Expression at the Neuromuscular Synapse

    Anthony O. Gramolini;Carina L. Dennis;Jonathon M. Tinsley;George S. Robertson

  • Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.

    Mei Sun;Maral Ouzounian;Geoffrey de Couto;Manyin Chen

  • Increased expression of utrophin in a slow vs. a fast muscle involves posttranscriptional events

    Anthony O. Gramolini;Guy Bélanger;Jennifer M. Thompson;Joe V. Chakkalakal

Frequent Co-Authors

Thomas Kislinger
Thomas Kislinger University of Toronto
David H. MacLennan
David H. MacLennan University of Toronto
Andrew Emili
Andrew Emili Boston University
Peter H. Backx
Peter H. Backx York University
Bernard J. Jasmin
Bernard J. Jasmin University of Ottawa
Peter Liu
Peter Liu University of Ottawa
Douglas S. Lee
Douglas S. Lee University Health Network
Gavin Y. Oudit
Gavin Y. Oudit University of Alberta
Kay E. Davies
Kay E. Davies University of Oxford
Hongbo Guo
Hongbo Guo Beihang University

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