World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
86
Citations
25035
World Ranking
2558
National Ranking
894

Overview

David D. Thomas is affiliated with the University of Minnesota in the United States. Their research spans multiple fields primarily including Biochemistry, Genetics and Molecular Biology with 135 publications, as well as Medicine with 113 publications. Within these broader fields, Thomas's work focuses notably on subfields such as Molecular Biology, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, Cell Biology, and Physiology.

Their main topics of research encompass various aspects of cardiovascular and molecular biology, including:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Effects of Exercise
  • Receptor Mechanisms and Signaling
  • Genetic Neurodegenerative Diseases
  • Muscle Physiology and Disorders

Thomas has contributed to numerous publications across several leading scientific journals. The most frequent publication venues include:

  • Biophysical Journal (35 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (19 publications)
  • Journal of Biological Chemistry (13 publications)
  • eLife (4 publications)
  • Scientific Reports (3 publications)

Their recent scientific papers reflect a diverse and advanced research portfolio:

  • "Allostery governs Cdk2 activation and differential recognition of CDK inhibitors," 2021, Nature Chemical Biology
  • "Direct detection of the myosin super-relaxed state and interacting-heads motif in solution," 2021, Journal of Biological Chemistry
  • "A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A," 2022, The EMBO Journal
  • "Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators," 2020, Skeletal Muscle
  • "RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays," 2020, Scientific Reports

Collaborations are an important aspect of Thomas's research activities. Frequent coauthors include:

  • Rǎzvan L. Cornea
  • Robyn T. Rebbeck
  • Samantha L. Yuen
  • Bengt Svensson
  • Andrew R. Thompson

Best Publications

  • Guidelines for carotid endarterectomy: A multidisciplinary consensus statement from the Ad Hoc committee, American Heart Association

    Wesley S. Moore;H.J.M. Barnett;Hugh G. Beebe;Eugene F. Bernstein

  • Gas sensor array based on metal-decorated carbon nanotubes.

    Alexander Star;Vikram Joshi;Sergei Skarupo;David Thomas

  • Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay

    Yoshie Harada;Katsuhiko Sakurada;Toshiaki Aoki;David D. Thomas

  • Rotational diffusion studied by passage saturation transfer electron paramagnetic resonance

    David D. Thomas;David D. Thomas;Larry R. Dalton;James S. Hyde;James S. Hyde

  • A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals.

    D. Thomas;S.C. Tovey;T.J. Collins;M.D. Bootman;M.D. Bootman

  • Orientation of spin-labeled myosin heads in glycerinated muscle fibers.

    David D Thomas;R. Cooke

  • Orientation of spin labels attached to cross-bridges in contracting muscle fibres

    Roger Cooke;Mark S. Crowder;David D. Thomas

  • Mutation and phosphorylation change the oligomeric structure of phospholamban in lipid bilayers

    Rǎzvan L. Cornea;Larry R. Jones;Joseph M. Autry;David D. Thomas

  • Fluorescence energy transfer in the rapid-diffusion limit.

    David D. Thomas;William F. Carlsen;Lubert Stryer

  • NMR Solution Structure and Topological Orientation of Monomeric Phospholamban in Dodecylphosphocholine Micelles

    Jamillah Zamoon;Alessandro Mascioni;David D. Thomas;Gianluigi Veglia

  • Nuclear calcium signalling by individual cytoplasmic calcium puffs

    Peter Lipp;David Thomas;Michael J. Berridge;Michael J. Berridge;Martin D. Bootman;Martin D. Bootman

  • Diffusion-Enhanced Fluorescence Energy Transfer

    L. Stryer;D. D. Thomas;C. F. Meares

  • Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.

    D Thomas;H Cherest;Y Surdin-Kerjan

  • A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction

    Josh E. Baker;Ingrid Brust-Mascher;Sampath Ramachandran;Leslie E. W. LaConte

  • Exciton Magnetic Resonance in Wurster's Blue Perchlorate

    D. D. Thomas;H. Keller;H. M. McConnell

  • A heteromeric complex containing the centromere binding factor 1 and two basic leucine zipper factors, Met4 and Met28, mediates the transcription activation of yeast sulfur metabolism.

    L Kuras;H Cherest;Y Surdin-Kerjan;D Thomas

  • Electron paramagnetic resonance reveals age-related myosin structural changes in rat skeletal muscle fibers

    Dawn A. Lowe;Jack T. Surek;David D. Thomas;LaDora V. Thompson

  • Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.

    D Thomas;L Kuras;R Barbey;H Cherest

  • Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin.

    John A. Rohde;Osha Roopnarine;David D. Thomas;Joseph M. Muretta

  • A Fluorescence Energy Transfer Method for Analyzing Protein Oligomeric Structure: Application to Phospholamban

    Ming Li;Laxma G. Reddy;Roberta Bennett;Norberto D. Silva

  • Cofilin Increases the Torsional Flexibility and Dynamics of Actin Filaments

    Ewa Prochniewicz;Neal Janson;David D. Thomas;Enrique M. De La Cruz

Frequent Co-Authors

Gianluigi Veglia
Gianluigi Veglia University of Minnesota
Donald M. Bers
Donald M. Bers University of California, Davis
Keith A. Olive
Keith A. Olive University of Minnesota
Larry R. Jones
Larry R. Jones Indiana University
David N. Schramm
David N. Schramm University of Chicago
Roger Cooke
Roger Cooke University of California, San Francisco
Martin D. Bootman
Martin D. Bootman The Open University
James M. Ervasti
James M. Ervasti University of Minnesota
Michael J. Berridge
Michael J. Berridge Babraham Institute
James S. Hyde
James S. Hyde Medical College of Wisconsin

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