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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
17332
World Ranking
15923
National Ranking
6614

Overview

James M. Ervasti is affiliated with the University of Minnesota in the United States, contributing extensively to research in the fields of biochemistry, genetics, molecular biology, and medicine. Their work spans several specialized subfields, including molecular biology, cell biology, cardiology and cardiovascular medicine, cellular and molecular neuroscience, and rehabilitation.

Ervasti's research focuses on key topics such as muscle physiology and disorders, cellular mechanics and interactions, exercise and physiological responses, adipose tissue and metabolism, cardiomyopathy and myosin studies, mitochondrial function and pathology, and RNA research and splicing. These topics reflect a diverse but interconnected range of biological processes and pathological conditions.

The scientist has contributed to several recent papers, highlighting ongoing research efforts across various biomedical domains:

  • Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy, 2020, Journal of the American College of Cardiology
  • Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators, 2020, Skeletal Muscle
  • Social stress is lethal in the mdx model of Duchenne muscular dystrophy, 2020, EBioMedicine
  • PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb, 2020, JCI Insight
  • Dystrophin missense mutations alter focal adhesion tension and mechanotransduction, 2022, Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Ervasti include Angus Lindsay, William M. Southern, Dawn A. Lowe, Lauren J. Sundby, and Wendy R. Gordon. These collaborations indicate a network of research relationships likely focused on muscle and cellular biology topics.

Ervasti's work has been published repeatedly in venues including bioRxiv (Cold Spring Harbor Laboratory), JCI Insight, The FASEB Journal, Journal of Biological Chemistry, and Biophysical Journal. Having multiple publications in these outlets suggests sustained research output in experimental and translational biomedical sciences.

Best Publications

  • Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix

    Oxana Ibraghimov-Beskrovnaya;James M. Ervasti;Cynthia J. Leveille;Clive A. Slaughter

  • A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin

    James M Ervasti;K. P. Campbell

  • Membrane organization of the dystrophin-glycoprotein complex

    James M. Ervasti;Kevin P. Campbell

  • Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle.

    James M. Ervasti;Kay Ohlendieck;Steven D. Kahl;Mitchell G. Gaver

  • Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.

    Kiichiro Matsumura;James M. Ervasti;Kay Ohlendieck;Steven D. Kahl

  • Costameres: The Achilles' heel of Herculean muscle

    James M. Ervasti

  • The Dystrophin Complex Forms a Mechanically Strong Link between the Sarcolemma and Costameric Actin

    Inna N. Rybakova;Jitandrakumar R. Patel;James M. Ervasti

  • Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle

    Kay Ohlendieck;James M. Ervasti;Kiichiro Matsumura;Steven D. Kahl

  • The Actin Gene Family: Function Follows Isoform

    Benjamin J. Perrin;James M. Ervasti

  • Dystrophin, its interactions with other proteins, and implications for muscular dystrophy.

    James M. Ervasti

  • Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemma

    Kay Ohlendieck;James M. Ervasti;Joseph B. Snook;Kevin P. Campbell

  • β-Actin specifically controls cell growth, migration, and the G-actin pool

    Tina M. Bunnell;Brandon J. Burbach;Yoji Shimizu;James M. Ervasti

  • A new model for the interaction of dystrophin with F-actin

    Inna N. Rybakova;Kurt J. Amann;James M. Ervasti

  • Purification of dystrophin from skeletal muscle.

    J M Ervasti;S D Kahl;K P Campbell

  • Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

    Duan Sun Zhang;Valeria Piazza;Valeria Piazza;Benjamin J. Perrin;Agnieszka K. Rzadzinska

  • A cluster of basic repeats in the dystrophin rod domain binds F-actin through an electrostatic interaction

    Kurt J. Amann;Brian A. Renley;James M. Ervasti

  • γ-Actin is required for cytoskeletal maintenance but not development

    Inna A. Belyantseva;Benjamin J. Perrin;Kevin J. Sonnemann;Mei Zhu

  • Dystrophin and the membrane skeleton.

    James M. Ervasti;Kevin P. Campbell

  • Dystrophin is a microtubule-associated protein

    Kurt W. Prins;Jill L. Humston;Amisha Mehta;Victoria Tate

  • Biology of the striated muscle dystrophin-glycoprotein complex.

    James M. Ervasti;Kevin J. Sonnemann

Frequent Co-Authors

Kevin P. Campbell
Kevin P. Campbell University of Iowa
David D. Thomas
David D. Thomas University of Minnesota
Kay Ohlendieck
Kay Ohlendieck National University of Ireland, Maynooth
Kevin M. Flanigan
Kevin M. Flanigan The Ohio State University
Daniel J. Garry
Daniel J. Garry University of Minnesota
James R. Mickelson
James R. Mickelson University of Minnesota
Peter D. Yurchenco
Peter D. Yurchenco Rutgers, The State University of New Jersey
Michael Kyba
Michael Kyba University of Minnesota
Kiyotoshi Sekiguchi
Kiyotoshi Sekiguchi Osaka University
Jeffrey S. Chamberlain
Jeffrey S. Chamberlain University of Washington

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