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D-Index & Metrics

Molecular Biology

D-Index
69
Citations
19066
World Ranking
1466
National Ranking
745

Overview

Michael Kyba is affiliated with the University of Minnesota in the United States. His research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a total of 101 publications, alongside Medicine, contributing 55 publications.

His work is focused on various subfields, including Molecular Biology, Genetics, Physiology, Cardiology and Cardiovascular Medicine, and Surgery. Key research topics encompass Muscle Physiology and Disorders, Congenital Heart Defects Research, Pluripotent Stem Cells Research, Tissue Engineering and Regenerative Medicine, Exercise and Physiological Responses, CRISPR and Genetic Engineering, and RNA Modifications and Cancer.

Among recent papers, notable examples include:

  • Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice (2020, Journal of Clinical Investigation)
  • Dux facilitates post-implantation development, but is not essential for zygotic genome activation (2020, Biology of Reproduction)
  • Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma (2021, Oncogenesis)
  • Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes (2022, Stem Cell Reports)
  • Proliferation and Maturation: Janus and the Art of Cardiac Tissue Engineering (2023, Circulation Research)

Frequent coauthors who have contributed to multiple publications with Michael Kyba include Darko Bosnakovski, Ahmed S. Shams, Erik A. Toso, Kathryn Vera, and Mary McConville.

Regular publication venues for their research include Stem Cell Reports, Cells, bioRxiv (Cold Spring Harbor Laboratory), Circulation Research, and Medicine & Science in Sports & Exercise.

Best Publications

  • White Fat Progenitor Cells Reside in the Adipose Vasculature

    Wei Tang;Daniel Zeve;Jae Myoung Suh;Darko Bosnakovski

  • HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors.

    Michael Kyba;Rita C.R. Perlingeiro;George Q. Daley;George Q. Daley

  • The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

    Andrew Keniry;David Oxley;Paul Monnier;Michael Kyba

  • Correction of a Genetic Defect by Nuclear Transplantation and Combined Cell and Gene Therapy

    William M. Rideout;Konrad Hochedlinger;Konrad Hochedlinger;Michael Kyba;George Q. Daley;George Q. Daley

  • Human ES- and iPS-Derived Myogenic Progenitors Restore DYSTROPHIN and Improve Contractility upon Transplantation in Dystrophic Mice

    Radbod Darabi;Robert W. Arpke;Stefan Irion;John T. Dimos

  • Facioscapulohumeral Dystrophy: Incomplete Suppression of a Retrotransposed Gene

    Lauren Snider;Linda N. Geng;Richard J. L. F. Lemmers;Michael Kyba

  • Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.

    Stephen M. Dang;Michael Kyba;Rita Perlingeiro;George Q. Daley

  • Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification.

    Antoine Bondue;Gaëlle Lapouge;Catherine Paulissen;Claudio Semeraro

  • Nuclear Transplantation, Embryonic Stem Cells, and the Potential for Cell Therapy

    Konrad Hochedlinger;Rudolf Jaenisch

  • Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.

    R. Coleman Lindsley;Jennifer G. Gill;Michael Kyba;Theresa L. Murphy

  • Generation of functional thyroid from embryonic stem cells.

    Francesco Antonica;Dominika Figini Kasprzyk;Robert Opitz;Michelina Iacovino

  • Functional skeletal muscle regeneration from differentiating embryonic stem cells

    Radbod Darabi;Kimberly Gehlbach;Robert M Bachoo;Shwetha Kamath

  • ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.

    Dongjun Lee;Changwon Park;Ho Lee;Jesse J. Lugus

  • An isogenetic myoblast expression screen identifies DUX4-mediated FSHD-associated molecular pathologies.

    Darko Bosnakovski;Zhaohui Xu;Eun Ji Gang;Cristi L Galindo

  • Caspase activity mediates the differentiation of embryonic stem cells.

    Jun Fujita;Ana M. Crane;Marlon K. Souza;Marion Dejosez

  • p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

    Abhinav K. Jain;Kendra Allton;Michelina Iacovino;Elisabeth Mahen

  • MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome

    Vaia Stavropoulou;Susanne Kaspar;Susanne Kaspar;Laurent Brault;Mathijs A. Sanders

  • Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo.

    Anwarul Ferdous;Arianna Caprioli;Michelina Iacovino;Cindy M. Martin;Cindy M. Martin

  • Zinc Finger Protein ZFP57 Requires Its Co-factor to Recruit DNA Methyltransferases and Maintains DNA Methylation Imprint in Embryonic Stem Cells via Its Transcriptional Repression Domain

    Xiaopan Zuo;Jipo Sheng;Ho Tak Lau;Carol M. McDonald

  • Mesp1 Coordinately Regulates Cardiovascular Fate Restriction and Epithelial-Mesenchymal Transition in Differentiating ESCs

    R. Coleman Lindsley;Jennifer G. Gill;Theresa L. Murphy;Ellen M. Langer

Frequent Co-Authors

Daniel J. Garry
Daniel J. Garry University of Minnesota
George Q. Daley
George Q. Daley Boston Children's Hospital
Richard P. Harvey
Richard P. Harvey Victor Chang Cardiac Research Institute
James A. Thomson
James A. Thomson University of California, Santa Barbara
Antoine H.F.M. Peters
Antoine H.F.M. Peters Friedrich Miescher Institute
Jakub Tolar
Jakub Tolar University of Minnesota
Ron Stewart
Ron Stewart Morgridge Institute for Research
Wolf Reik
Wolf Reik Babraham Institute
Eric N. Olson
Eric N. Olson The University of Texas Southwestern Medical Center
Timothy J. Kamp
Timothy J. Kamp University of Wisconsin–Madison

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Related Online Degrees & Career Pathways

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