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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12275
World Ranking
14356
National Ranking
1127

Overview

Valerie Kouskoff is affiliated with the University of Manchester in the United Kingdom. Their research spans several fields within the biomedical sciences, including biochemistry, genetics, molecular biology, and medicine. The primary subfields of study focus on molecular biology, cell biology, hematology, immunology, and oncology.

The scientist's recent publications reveal a focus on hematopoiesis, gene regulation, and cancer biology. Key papers include:

  • Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE, 2021, Blood
  • RUNX1 Dosage in Development and Cancer., 2020, PubMed
  • In vitro differentiation of human embryonic stem cells to hemogenic endothelium and blood progenitors via embryoid body formation, 2021, STAR Protocols
  • The oncogenic fusion protein TAZ::CAMTA1 promotes genomic instability and senescence through hypertranscription, 2023, Communications Biology
  • The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner, 2023, The EMBO Journal

Valerie Kouskoff's research topics frequently intersect several areas, prominently including:

  • Zebrafish biomedical research applications
  • Hippo pathway signaling and YAP/TAZ
  • Acute myeloid leukemia research
  • Pluripotent stem cells research
  • Ubiquitin and proteasome pathways
  • Protein degradation and inhibitors
  • Lymphatic system and diseases

The scientist has published in a variety of journals, with notable frequent venues including bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Cell and Developmental Biology, Blood, Communications Biology, and PubMed.

Among frequent collaborators are Georges Lacaud with eight joint publications, followed by Michael Lie-A-Ling, Syed Murtuza Baker, Roberto Paredes, and Eva García-Alegría, each with four publications alongside Valerie Kouskoff.

Best Publications

  • Development of definitive endoderm from embryonic stem cells in culture

    Atsushi Kubo;Katsunori Shinozaki;John M. Shannon;Valerie Kouskoff

  • Organ-Specific Disease Provoked by Systemic Autoimmunity

    Valérie Kouskoff;Anne-Sophie Korganow;Véronique Duchatelle;Claude Degott

  • Haemangioblast commitment is initiated in the primitive streak of the mouse embryo.

    Tara L. Huber;Valerie Kouskoff;Valerie Kouskoff;H. Joerg Fehling;James Palis

  • The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage.

    Christophe Lancrin;Patrycja Sroczynska;Catherine Stephenson;Terence D Allen

  • Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation

    Hans Jörg Fehling;Georges Lacaud;Atsushi Kubo;Marion Kennedy

  • Decoding the regulatory network of early blood development from single-cell gene expression measurements

    Victoria Moignard;Steven Woodhouse;Laleh Haghverdi;Andrew J Lilly

  • Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro.

    Georges Lacaud;Lia Gore;Marion Kennedy;Valerie Kouskoff

  • Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

    John E. Pimanda;Katrin Ottersbach;Kathy Knezevic;Sarah Kinston

  • Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.

    Debbie K. Goode;Nadine Obier;M.S. Vijayabaskar;Michael Lie-A-Ling

  • Cassette vectors directing expression of T cell receptor genes in transgenic mice

    Valérie Kouskoff;Kathy Signorelli;Christophe Benoist;Diane Mathis

  • Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation.

    Valerie Kouskoff;Georges Lacaud;Staci Schwantz;Hans Jöerg Fehling

  • The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF

    Stella Pearson;Patrycja Sroczynska;Georges Lacaud;Valerie Kouskoff

  • GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1

    Roshana Thambyrajah;Milena Mazan;Milena Mazan;Rahima Patel;Victoria Moignard

  • RUNX transcription factors: orchestrators of development

    Renaud Mevel;Julia E. Draper;Michael Lie-a-Ling;Valerie Kouskoff

  • RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

    Monika Lichtinger;Richard Ingram;Rebecca Hannah;Dorothee Müller

  • Visualization of the genesis and fate of isotype-switched B cells during a primary immune response.

    Kathryn A. Pape;Valerie Kouskoff;David Nemazee;H. Lucy Tang

  • GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.

    Christophe Lancrin;Milena Mazan;Monika Stefanska;Rahima Patel

  • Antigens Varying in Affinity for the B Cell Receptor Induce Differential B Lymphocyte Responses

    Valerie Kouskoff;Sara Famiglietti;Georges Lacaud;Paul Lang

  • Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells

    Kiran Batta;Magdalena Florkowska;Valerie Kouskoff;Georges Lacaud

  • V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling

    Marc Hertz;Valérie Kouskoff;Tetsuya Nakamura;David Nemazee

Frequent Co-Authors

Georges Lacaud
Georges Lacaud University of Manchester
Berthold Göttgens
Berthold Göttgens University of Cambridge
Constanze Bonifer
Constanze Bonifer University of Birmingham
Gordon Keller
Gordon Keller University of Toronto
Diane Mathis
Diane Mathis Harvard University
Christophe Benoist
Christophe Benoist Harvard University
David Nemazee
David Nemazee Scripps Research Institute
Daniel G. Tenen
Daniel G. Tenen National University of Singapore
Fabian J. Theis
Fabian J. Theis Technical University of Munich

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