World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
6748
World Ranking
19304
National Ranking
7887

Overview

Warren D. Kruger is affiliated with Fox Chase Cancer Center in the United States. Their research primarily falls within the broad discipline of Biochemistry, Genetics and Molecular Biology, with a concentration in subfields such as Molecular Biology, Biochemistry, Rheumatology, Clinical Biochemistry, and Pediatrics, Perinatology and Child Health.

The scientist's work covers a range of topics including:

  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Folate and B Vitamins Research
  • Sulfur Compounds in Biology
  • Metabolism and Genetic Disorders
  • Amino Acid Enzymes and Metabolism

Warren D. Kruger has been involved in several published papers with various coauthors. Selected recent publications include:

  • Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression, 2020, Cancer Discovery
  • CRY1-CBS binding regulates circadian clock function and metabolism, 2020, FEBS Journal
  • Synthesis of Sulfides and Persulfides Is Not Impeded by Disruption of Three Canonical Enzymes in Sulfur Metabolism, 2023, Antioxidants
  • Recent therapeutic approaches to cystathionine beta-synthase-deficient homocystinuria, 2022, British Journal of Pharmacology
  • NEDD9 sustains hexokinase expression to promote glycolysis, 2022, Oncogenesis

Frequent coauthors collaborating with this researcher include:

  • Nisha Padmanabhan
  • Arnoud Boot
  • Kevin Lim
  • Supriya Srivastava
  • Shuwen Chen

The scientist's publications appear in a variety of venues, with notable frequency in:

  • OPAL (Open@LaTrobe) (La Trobe University)
  • Genome Biology
  • Journal of Inherited Metabolic Disease
  • Cancer Discovery
  • Antioxidants

Best Publications

  • Cystathionine β‐synthase mutations in homocystinuria

    Jan P. Kraus;Miroslav Janošík;Viktor Kožich;Roseann Mandell

  • Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity.

    Shinichi Taoka;Sunil Ohja;Xiaoyin Shan;Warren D. Kruger

  • Cloning, Mapping and RNA Analysis of the Human Methionine Synthase Gene

    Yunan N. Li;Sumedha Gulati;Priscilla J. Baker;Lawrence C. Brody

  • The role of cystathionine beta-synthase in homocysteine metabolism.

    Kwang-Hwan Jhee;Warren D. Kruger

  • Hyperhomocysteinemia Promotes Inflammatory Monocyte Generation and Accelerates Atherosclerosis in Transgenic Cystathionine β-Synthase–Deficient Mice

    Daqing Zhang;Xiaohua Jiang;Pu Fang;Yan Yan

  • Severe Hyperhomocysteinemia Promotes Bone Marrow–Derived and Resident Inflammatory Monocyte Differentiation and Atherosclerosis in LDLr/CBS-Deficient Mice

    Daqing Zhang;Pu Fang;Xiaohua Jiang;Jun Nelson

  • Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12.

    Arlene Lobo;Arabi Naso;Kristopher Arheart;Warren D Kruger

  • Characterization of transsulfuration and cysteine biosynthetic pathways in the protozoan hemoflagellate, Trypanosoma cruzi. Isolation and molecular characterization of cystathionine beta-synthase and serine acetyltransferase from Trypanosoma.

    Tomoyoshi Nozaki;Yasuo Shigeta;Yumiko Saito-Nakano;Mihoko Imada

  • Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression.

    Ralph Francescone;Débora Barbosa Vendramini-Costa;Janusz Franco-Barraza;Jessica Wagner

  • Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice

    Hieronim Jakubowski;Joanna Perła-Kaján;Richard H. Finnell;Robert M. Cabrera

  • Modulation of Cystathionine β-Synthase Level Regulates Total Serum Homocysteine in Mice

    Liqun Wang;Kwang Hwan Jhee;Xiang Hua;Patricia M. DiBello

  • Tsc1+ and tsc2+ Regulate Arginine Uptake and Metabolism in Schizosaccharomyces pombe*

    Marjon van Slegtenhorst;Erikka Carr;Radka Stoyanova;Warren D. Kruger

  • Expression of mutant human cystathionine β-synthase rescues neonatal lethality but not homocystinuria in a mouse model

    Liqun Wang;Xulin Chen;Baiqing Tang;Xiang Hua

  • Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia

    Sapna Gupta;Jirko Kühnisch;Aladdin Mustafa;Sarka Lhotak

  • The Birt-Hogg-Dube and Tuberous Sclerosis Complex Homologs Have Opposing Roles in Amino Acid Homeostasis in Schizosaccharomyces pombe*

    Marjon van Slegtenhorst;Damir Khabibullin;Tiffiney R. Hartman;Emmanuelle Nicolas

  • Methylthioadenosine Phosphorylase Regulates Ornithine Decarboxylase by Production of Downstream Metabolites

    Ahmad L. Subhi;Paula Diegelman;Carl W. Porter;Baiqing Tang

  • Hyperhomocysteinemia Potentiates Hyperglycemia-induced Inflammatory Monocyte Differentiation and Atherosclerosis

    Pu Fang;Daqing Zhang;Zhongjian Cheng;Chenghui Yan

  • Functional Modeling of Vitamin Responsiveness in Yeast: A Common Pyridoxine-Responsive Cystathionine β-Synthase Mutation in Homocystinuria

    Cecilia E. Kim;Paula M. Gallagher;Anne B. Guttormsen;Helga Refsum

  • Diet-Induced Hyperhomocysteinemia Increases Amyloid-β Formation and Deposition in a Mouse Model of Alzheimers Disease

    J.-M. Zhuo;G. S. Portugal;W. D. Kruger;H. Wang

  • NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast derived nutritional supply and immunosuppression

    Ralph Francescone;Débora Barbosa Vendramini-Costa;Janusz Franco-Barraza;Jessica Wagner

Frequent Co-Authors

Domenico Praticò
Domenico Praticò Temple University
Wafik S. El-Deiry
Wafik S. El-Deiry Brown University
Andres J. P. Klein-Szanto
Andres J. P. Klein-Szanto Fox Chase Cancer Center
Henk J. Blom
Henk J. Blom Erasmus MC
William Durante
William Durante University of Missouri
Edna Cukierman
Edna Cukierman Fox Chase Cancer Center
Beat Thöny
Beat Thöny University of Zurich
Jan P. Kraus
Jan P. Kraus University of Colorado Denver
Rima Rozen
Rima Rozen McGill University

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