D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 105 Citations 47,218 423 World Ranking 3942 National Ranking 139

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

His primary areas of study are Homocysteine, Internal medicine, Endocrinology, Methylenetetrahydrofolate reductase and Risk factor. Henk J. Blom studies Homocysteine, namely Hyperhomocysteinemia. Henk J. Blom combines subjects such as Gastroenterology and Genotype with his study of Internal medicine.

The study incorporates disciplines such as Neural tube, Reductase and Vascular disease in addition to Endocrinology. The various areas that he examines in his Methylenetetrahydrofolate reductase study include Thermolabile, Methotrexate, Rheumatoid arthritis and Point mutation. His Risk factor study combines topics in areas such as Dydrogesterone, Central nervous system disease, Postmenopausal women, Case-control study and Mutation.

His most cited work include:

  • A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase (4996 citations)
  • A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? (1368 citations)
  • Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials (916 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Homocysteine, Endocrinology, Hyperhomocysteinemia and Methylenetetrahydrofolate reductase. His biological study deals with issues like Genotype, which deal with fields such as Allele. His research investigates the connection between Homocysteine and topics such as Cystathionine beta synthase that intersect with problems in Mutation.

His Endocrinology research focuses on Methylation and how it relates to Molecular biology. His work carried out in the field of Hyperhomocysteinemia brings together such families of science as Thrombosis, Venous thrombosis, Surgery and Cardiology. His Methylenetetrahydrofolate reductase research integrates issues from Reductase and Mutation.

He most often published in these fields:

  • Internal medicine (66.51%)
  • Homocysteine (54.88%)
  • Endocrinology (55.35%)

What were the highlights of his more recent work (between 2010-2019)?

  • Internal medicine (66.51%)
  • Homocysteine (54.88%)
  • Endocrinology (55.35%)

In recent papers he was focusing on the following fields of study:

His main research concerns Internal medicine, Homocysteine, Endocrinology, Biochemistry and Methionine. His Internal medicine research includes themes of Gastroenterology, Genetics and Hypermethioninemia. He is involved in the study of Homocysteine that focuses on Hyperhomocysteinemia in particular.

His Hyperhomocysteinemia research incorporates themes from Pregnancy, Nitric oxide, Surgery and Osteoporosis. His Endocrinology study incorporates themes from Methylation, Cerebrospinal fluid and Dimethylglycine. His Methionine study combines topics from a wide range of disciplines, such as Epilepsy, Bioinformatics and Pathology.

Between 2010 and 2019, his most popular works were:

  • Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects (284 citations)
  • Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species (159 citations)
  • Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease (113 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

His primary areas of investigation include Internal medicine, Endocrinology, Homocysteine, Methionine and Methylenetetrahydrofolate reductase. The Internal medicine study combines topics in areas such as Hypermethioninemia, Genetics, Gastroenterology, Enzyme and Epilepsy. His research in Endocrinology intersects with topics in Neural tube, Missense mutation, Biochemistry and DNA methylation.

His study of Hyperhomocysteinemia is a part of Homocysteine. In Hyperhomocysteinemia, he works on issues like B vitamins, which are connected to Histone arginine methylation, Protein methylation and Histone methylation. Henk J. Blom works mostly in the field of Methylenetetrahydrofolate reductase, limiting it down to topics relating to Risk factor and, in certain cases, Surgery, Adverse effect and Mendelian Randomization Analysis, as a part of the same area of interest.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

P. Frosst;H. J. Blom;R. Milos;P. Goyette.
Nature Genetics (1995)

7363 Citations

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

Nathalie M.J. van der Put;Fons Gabreëls;Erik M.B. Stevens;Jan A.M. Smeitink.
American Journal of Human Genetics (1998)

2004 Citations

Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials

L.E. Brattstrom;M. den Heijer;H.J. Blom;G. Bos.
BMJ (1998)

1502 Citations

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis

M. Den Heijer;T. Koster;H. J. Blom;G. M. J. Bos.
The New England Journal of Medicine (1996)

1447 Citations

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

Mariska Klerk;Petra Verhoef;Robert Clarke;Henk J. Blom.
JAMA (2002)

1251 Citations

Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida

N.M.J. van der Put;F.J.M. Trijbels;L.P. van den Heuvel;H.J. Blom.
The Lancet (1995)

1119 Citations

Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

L. A. J. Kluijtmans;L. P. W. J. Van Den Heuvel;G. H. J. Boers;P. Frosst.
American Journal of Human Genetics (1996)

888 Citations

Neural tube defects and folate: case far from closed

Henk J. Blom;Gary M. Shaw;Martin den Heijer;Richard H. Finnell.
Nature Reviews Neuroscience (2006)

589 Citations

Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia.

Astrid M. T. Engbersen;Diana G. Franken;Godfried H. J. Boers;Erik M. B. Stevens.
American Journal of Human Genetics (1995)

584 Citations

Maternal hyperhomocysteinemia : a risk factor for neural-tube defects ?

Régine P.M. Steegers-Theunissen;Godfried H.J. Boers;Frans J.M. Trijbels;James D. Finkelstein.
Metabolism-clinical and Experimental (1994)

560 Citations

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