World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
14170
World Ranking
8747
National Ranking
230

Overview

Cornelis Jakobs is affiliated with VU University Medical Center in the Netherlands. Their research spans key areas within biochemistry, genetics, molecular biology, and physics and astronomy. The scientist's documented work notably covers subfields such as biophysics, structural biology, and atomic and molecular physics, including optics.

Jakobs' research topics focus on advanced microscopy techniques, highlighting:

  • Advanced Fluorescence Microscopy Techniques
  • Advanced Electron Microscopy Techniques and Applications
  • Force Microscopy Techniques and Applications

The scientist has contributed to scholarship in multiple frequent publication venues, with The Journal of Cell Biology noted as a primary forum.

Recent published work includes the paper titled "Presynapses contain distinct actin nanostructures" from 2023. This study appeared in The Journal of Cell Biology and has been cited 35 times. The work involved collaboration with various co-authors, including:

  • Dominic Bingham
  • Florian Wernert
  • Fanny Boroni-Rueda
  • Nicolas Jullien
  • Eva-Maria Schentarra

The body of work demonstrates interdisciplinary expertise, integrating methodologies from biochemistry and molecular biology with precision imaging techniques applicable in cellular and structural analysis. The scientist's association with advanced microscopy and force measurement underscores a focus on nanoscale cellular structures and molecular dynamics.

Best Publications

  • Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

    Markus Ralser;Mirjam M Wamelink;Axel Kowald;Birgit Gerisch

  • Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study.

    Ellen K. Hoogeveen;Pieter J. Kostense;Pieter J. Beks;Albert J. C. Mackaay

  • Mutations in antiquitin in individuals with pyridoxine-dependent seizures

    Philippa B Mills;Eduard Struys;Cornelis Jakobs;Barbara Plecko

  • Increased homocysteine and S-adenosylhomocysteine concentrations and DNA hypomethylation in vascular disease

    Rita Castro;Isabel Rivera;Eduard A. Struys;Erwin E.W. Jansen

  • Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study.

    Ellen K. Hoogeveen;Pieter J. Kostense;Cornelis Jakobs;Jacqueline M. Dekker

  • X-Linked Creatine-Transporter Gene (SLC6A8) Defect: A New Creatine-Deficiency Syndrome

    Gajja S. Salomons;Silvy J.M. van Dooren;Nanda M. Verhoeven;Kim M. Cecil

  • Pyridoxine dependent epilepsy and antiquitin deficiency: clinical and molecular characteristics and recommendations for diagnosis, treatment and follow-up.

    Sylvia Stockler;Barbara Plecko;Sidney M. Gospe;Marion Coulter-Mackie

  • Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency.

    A. B. van Kuilenburg;P. Vreken;N. G. Abeling;H. D. Bakker

  • Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency)

    Philippa B. Mills;Emma J. Footitt;Kevin A. Mills;Karin Tuschl

  • High prevalence of SLC6A8 deficiency in X-linked mental retardation

    Efraim H. Rosenberg;Ligia S. Almeida;Tjitske Kleefstra;Rose S. deGrauw

  • Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells

    Nana-Maria Grüning;Mark Rinnerthaler;Katharina Bluemlein;Michael Mülleder

  • Measurement of Urinary d- and l-2-Hydroxyglutarate Enantiomers by Stable-Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry after Derivatization with Diacetyl-l-Tartaric Anhydride

    Eduard A. Struys;Erwin E.W. Jansen;Nanda M. Verhoeven;Cornelis Jakobs

  • Homocysteine and methionine metabolism in ESRD: A stable isotope study

    Coen Van Guldener;Wim Kulik;Ruud Berger;Denise A. Dijkstra

  • Irreversible brain creatine deficiency with elevated serum and urine creatine: a creatine transporter defect?

    Kim M. Cecil;Gajja S. Salomons;William S. Ball;Brenda Wong

  • A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth.

    Markus Ralser;Mirjam M. Wamelink;Eduard A. Struys;Christian Joppich

  • Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency.

    Shinjiro Akaboshi;Boris M. Hogema;Boris M. Hogema;Boris M. Hogema;Andrea Novelletto;Patrizia Malaspina

  • Biochemical and molecular characterization of 18 patients with pyridoxine-dependent epilepsy and mutations of the antiquitin (ALDH7A1) gene†

    Barbara Plecko;Karl Paul;Eduard Paschke;Sylvia Stoeckler-Ipsiroglu

  • SUDDEN INFANT DEATH AND LONG-CHAIN 3-HYDROXYACYL-CoA DEHYDROGENASE

    R.J.A. Wanders;M. Duran;L. Ijlst;J.P. De Jager

  • Exocytotic release of creatine in rat brain.

    Ligia S. Almeida;Gajja S. Salomons;Francois Hogenboom;Cornelis Jakobs

  • The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response.

    Antje Krüger;Nana-Maria Grüning;Mirjam M.C. Wamelink;Martin Kerick

Frequent Co-Authors

Ronald J.A. Wanders
Ronald J.A. Wanders University of Amsterdam
Coen D.A. Stehouwer
Coen D.A. Stehouwer Maastricht University
Lex M. Bouter
Lex M. Bouter Vrije Universiteit Amsterdam
K. Michael Gibson
K. Michael Gibson Washington State University Spokane
Jacqueline M. Dekker
Jacqueline M. Dekker VU University Medical Center
Henk J. Blom
Henk J. Blom Erasmus MC
Markus Ralser
Markus Ralser Charité - University Medicine Berlin
Ron A. Wevers
Ron A. Wevers Radboud University
Giel Nijpels
Giel Nijpels VU University Medical Center

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