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Biology and Biochemistry

D-Index
44
Citations
6251
World Ranking
19321
National Ranking
7892

Overview

K. Michael Gibson is affiliated with Washington State University Spokane in the United States. Their research spans key areas within biochemistry, genetics, and molecular biology, with a total of 58 publications in these fields. Medicine is also a significant focus, accounting for 34 of their scholarly works.

Their specific expertise includes subfields such as molecular biology, physiology, clinical biochemistry, pathology and forensic medicine, and cellular and molecular neuroscience. These areas reflect the depth and diversity of their scientific investigations.

K. Michael Gibson's research topics cover several prominent domains:

  • Metabolism and Genetic Disorders
  • Metabolomics and Mass Spectrometry Studies
  • Diet and Metabolism Studies
  • Neuroscience and Neuropharmacology Research
  • Alcohol Consumption and Health Effects
  • Amino Acid Enzymes and Metabolism
  • Cancer, Hypoxia, and Metabolism

The frequent collaborators in their research include Jean-Baptiste Roullet, Phillip L. Pearl, Melissa L. DiBacco, Trevor O. Kirby, and Dana C. Walters. These partnerships have contributed to a concentrated body of work across various high-impact publications.

Publication venues that regularly feature Gibson's research are:

  • Journal of Child Neurology
  • The Journal of Immunology
  • Molecular Genetics and Metabolism
  • Metabolic Brain Disease
  • Neurology

Selected recent papers by K. Michael Gibson include:

  • "Farnesol induces protection against murine CNS inflammatory demyelination and modifies gut microbiome," 2021, Clinical Immunology
  • "Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes," 2020, Metabolic Brain Disease
  • "Novel ALDH5A1 variants and genotype," 2020, Neurology
  • "Succinic Semialdehyde Dehydrogenase Deficiency: Review of the Natural History Study," 2021, Journal of Child Neurology
  • "The presence and severity of epilepsy coincide with reduced γ-aminobutyrate and cortical excitatory markers in succinic semialdehyde dehydrogenase deficiency," 2023, Epilepsia

Best Publications

  • Gamma-hydroxybutyric acid.

    O. Carter Snead;K. Michael Gibson

  • From the street to the brain: neurobiology of the recreational drug γ-hydroxybutyric acid

    C.Guin Ting Wong;K.Michael Gibson;O.Carter Snead

  • IDH2 Mutations in Patients with d-2-Hydroxyglutaric Aciduria

    Martijn Kranendijk;Eduard A. Struys;Emile van Schaftingen;K. Michael Gibson

  • Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase.

    Boris M. Hogema;Boris M. Hogema;Boris M. Hogema;Maneesh Gupta;Henry Senephansiri;Terry G. Burlingame

  • Arginase Plays a Pivotal Role in Polyamine Precursor Metabolism in Leishmania CHARACTERIZATION OF GENE DELETION MUTANTS

    Sigrid C. Roberts;Michael J. Tancer;Michelle R. Polinsky;K. Michael Gibson

  • Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency.

    Shinjiro Akaboshi;Boris M. Hogema;Boris M. Hogema;Boris M. Hogema;Andrea Novelletto;Patrizia Malaspina

  • Succinic semialdehyde dehydrogenase deficiency in children and adults

    Phillip L. Pearl;Edward J. Novotny;Maria T. Acosta;Cornelis Jakobs

  • 2-Methylbutyryl-coenzyme A dehydrogenase deficiency : A new inborn error of L-isoleucine metabolism

    K Michael Gibson;Terry G Burlingame;Boris Hogema;Cornelis Jakobs

  • γ-Hydroxybutyric Acid

    C. Guin Ting Wong;Katherine F. Y. Chan;K. Michael Gibson;O. Carter Snead

  • Maleylacetoacetate Isomerase (MAAI/GSTZ)-Deficient Mice Reveal a Glutathione-Dependent Nonenzymatic Bypass in Tyrosine Catabolism

    José Manuel Fernández-Cañón;Manfred W. Baetscher;Milton Finegold;Terry Burlingame

  • Mevalonate kinase deficiency: enlarging the clinical and biochemical spectrum.

    Viola Prietsch;Ertan Mayatepek;Hermann Krastel;Dorothea Haas

  • Significant behavioral disturbances in succinic semialdehyde dehydrogenase (SSADH) deficiency (Gamma-Hydroxybutyric aciduria)

    K.Michael Gibson;Maneesh Gupta;Phillip L. Pearl;Mendel Tuchman

  • Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome.

    Sander M. Houten;Janet Koster;Gerrit Jan Romeijn;Joost Frenkel

  • Therapeutic Intervention in Mice Deficient for Succinate Semialdehyde Dehydrogenase (γ-Hydroxybutyric Aciduria)

    Maneesh Gupta;Rachel Greven;Erwin E. W. Jansen;Cornelis Jakobs

  • The molecular basis of 3-methylcrotonylglycinuria, a disorder of leucine catabolism.

    M.Esther Gallardo;Lourdes R. Desviat;José M. Rodríguez;Jorge Esparza-Gordillo

  • Highly Stable and Sensitive Fluorescent Probes (LysoProbes) for Lysosomal Labeling and Tracking

    Nazmiye B. Yapici;Yue Bi;Pengfei Li;Xin Chen

  • Oxidation of 4‐hydroxy‐2‐nonenal by succinic semialdehyde dehydrogenase (ALDH5A)

    Tonya C. Murphy;Venkataraman Amarnath;K. Michael Gibson;Matthew J. Picklo

  • Lysosomal Targeting with Stable and Sensitive Fluorescent Probes (Superior LysoProbes): Applications for Lysosome Labeling and Tracking during Apoptosis

    Xin Chen;Yue Bi;Tianyang Wang;Pengfei Li

  • Cloning and mutational analysis of human malonyl-coenzyme A decarboxylase

    Jimin Gao;Lewis Waber;Michael J. Bennett;K. Michael Gibson

  • Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition

    Ronak Lakhani;Kara R Vogel;Andreas Till;Jingjing Liu

Frequent Co-Authors

Phillip L. Pearl
Phillip L. Pearl Boston Children's Hospital
Teodoro Bottiglieri
Teodoro Bottiglieri Baylor University
O. Carter Snead
O. Carter Snead University of Toronto
Cornelis Jakobs
Cornelis Jakobs VU University Medical Center
Markus Grompe
Markus Grompe Oregon Health & Science University
Piero Rinaldo
Piero Rinaldo Mayo Clinic
Jerry Vockley
Jerry Vockley University of Pittsburgh
William H. Theodore
William H. Theodore National Institutes of Health
Andrea Novelletto
Andrea Novelletto University of Rome Tor Vergata
Suresh Subramani
Suresh Subramani University of California, San Diego

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