World's Best Scientists 2026 revealed!
Teodoro Bottiglieri

Teodoro Bottiglieri

D-Index & Metrics

Neuroscience

D-Index
81
Citations
22427
World Ranking
1581
National Ranking
776

Overview

Teodoro Bottiglieri is affiliated with Baylor University in the United States and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work frequently intersects with subfields such as Rheumatology, Molecular Biology, Physiology, Pediatrics, Perinatology and Child Health, as well as Obstetrics and Gynecology.

The scientist's main research topics include Folate and B Vitamins Research, Birth, Development, and Health, Diet and Metabolism Studies, Metabolism and Genetic Disorders, Metabolomics and Mass Spectrometry Studies, Pregnancy and Preeclampsia Studies, and Nutritional Studies and Diet.

Recent significant publications authored or co-authored by Bottiglieri include the following:

  • Targeted Metabolomic Analysis in Alzheimer's Disease Plasma and Brain Tissue in Non-Hispanic Whites (2022), Journal of Alzheimer s Disease
  • Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health (2021), Science Translational Medicine
  • Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis (2020), Epigenetics
  • Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson's Disease Progression (2020), Movement Disorders
  • One-Carbon Metabolism in Alzheimer's Disease and Parkinson's Disease Brain Tissue (2022), Nutrients

Bottiglieri frequently publishes in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nutrients
  • Current Developments in Nutrition
  • Molecular Nutrition & Food Research
  • Journal of Nutrition

Their collaboration network includes a number of frequent co-authors, such as:

  • Brandi Wasek
  • Erland Arning
  • Karel Kalecký
  • Paula Ashcraft
  • Nafisa M. Jadavji

Best Publications

  • Homocysteine, folate, methylation, and monoamine metabolism in depression

    Teodoro Bottiglieri;Malcolm Laundy;Richard Crellin;Brian K Toone

  • Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

    Zhoutao Chen;Andrew C. Karaplis;Susan L. Ackerman;Igor P. Pogribny

  • GABA, γ-hydroxybutyric acid, and neurological disease

    C. Guin Ting Wong;Teodoro Bottiglieri;O. Carter Snead

  • High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease: A Randomized Controlled Trial

    Paul S. Aisen;Lon S. Schneider;Mary Sano;Ramon Diaz-Arrastia

  • Enhancement of recovery from psychiatric illness by methylfolate

    T. Bottiglieri;K. Hyland;M. Laundy;P. Godfrey

  • Folate, Vitamin B12, and Neuropsychiatric Disorders

    Teodoro Bottiglieri

  • Folate, vitamin B12, and homocysteine in major depressive disorder.

    Maurizio Fava;Joseph S. Borus;Jonathan E. Alpert;Andrew A. Nierenberg

  • Homocysteine and folate metabolism in depression.

    Teodoro Bottiglieri

  • Plasma β-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy

    M. E. Gurol;M. C. Irizarry;E. E. Smith;S. Raju

  • Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine.

    T. Bottiglieri;P. Godfrey;T. Flynn;M. W. P. Carney

  • High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis.

    Rabindra Tirouvanziam;Carol K. Conrad;Teodoro Bottiglieri;Leonore A. Herzenberg

  • L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials.

    George I. Papakostas;Richard C. Shelton;John M. Zajecka;Bijan Etemad

  • Homocysteine and Dementia: An International Consensus Statement.

    A. David Smith;Helga Refsum;Teodoro Bottiglieri;Michael Fenech

  • The Central Role of Endothelial Dysfunction in Cardiorenal Syndrome

    Jun Zhang;Teodoro Bottiglieri;Peter A. McCullough

  • Cerebral Vascular Dysfunction Mediated by Superoxide in Hyperhomocysteinemic Mice

    Sanjana Dayal;Erland Arning;Teodoro Bottiglieri;Rainer H. Böger

  • Protein Phosphatase 2A Methyltransferase Links Homocysteine Metabolism with Tau and Amyloid Precursor Protein Regulation

    Estelle Sontag;Viyada Nunbhakdi-Craig;Jean-Marie Sontag;Ramon Diaz-Arrastia

  • Endothelial Dysfunction and Elevation of S-Adenosylhomocysteine in Cystathionine β-Synthase–Deficient Mice

    Sanjana Dayal;Teodoro Bottiglieri;Erland Arning;Nobuyo Maeda

  • The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.

    Teodoro Bottiglieri;Keith Hyland;Edward H. Reynolds

  • Elevated Prenatal Homocysteine Levels as a Risk Factor for Schizophrenia

    Alan S. Brown;Teodoro Bottiglieri;Catherine A. Schaefer;Charles P. Quesenberry

  • Elevation of homocysteine and excitatory amino acid neurotransmitters in the CSF of children who receive methotrexate for the treatment of cancer.

    C T Quinn;J C Griener;T Bottiglieri;K Hyland

  • Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine

    Elango Kathirvel;Kengathevy Morgan;Kengathevy Morgan;Ganesh Nandgiri;Brian C. Sandoval

  • Elevated plasma homocysteine level in patients with Parkinson disease: motor, affective, and cognitive associations.

    Padraig E O'Suilleabhain;Victor Sung;Carlos Hernandez;Laura J Lacritz

  • Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase.

    Boris M. Hogema;Boris M. Hogema;Boris M. Hogema;Maneesh Gupta;Henry Senephansiri;Terry G. Burlingame

  • High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

    Paul S. Aisen;Lon S. Schneider;Mary Sano;Ramon Diaz-Arrastia

Frequent Co-Authors

George I. Papakostas
George I. Papakostas Harvard University
David Mischoulon
David Mischoulon Harvard University
Phillip L. Pearl
Phillip L. Pearl Boston Children's Hospital
Trilochan Sahoo
Trilochan Sahoo Baylor College of Medicine
Leonore A. Herzenberg
Leonore A. Herzenberg Stanford University
Joshua L. Roffman
Joshua L. Roffman Harvard University
O. Carter Snead
O. Carter Snead University of Toronto

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're interested in neuroscience, it’s valuable to explore related online degrees and career pathways. Many students choose to enhance their knowledge in fields such as social work, psychology, or behavior analysis, as these areas overlap with neuroscience in research, clinical, and community settings.

For those considering a helping profession, an online msw (Master of Social Work) is a practical choice, especially for students seeking affordable and flexible learning options. If speeding up your education is a priority, an accelerated msw program online lets you gain advanced social work credentials in less time.

Those drawn to behavioral science can train to become a Board Certified Behavior Analyst with a bcba school online. This path is in demand for roles supporting individuals with behavioral and neurodevelopmental disorders. Psychology remains a core foundation for neuroscience-related careers, and accelerated psychology programs online offer a fast, flexible way to deepen your understanding of human behavior and cognition.

Exploring these online programs expands your career options in neuroscience and related fields, letting you tailor your education to match your interests and goals.

Best Scientists Citing Teodoro Bottiglieri

Trending Scientists

Recently Published Articles